Okubo Torahiko

オオクボトラヒコ | Okubo Torahiko

Affiliation and department：
Job title： Lecturer
Homepage URL (1)： https://www.hs.hokudai.ac.jp/yamaguchi/

Research field (5)： Hygiene and public health (non-laboratory) , Hygiene and public health (laboratory) , Other , Bacteriology , Ecology and environmental science

Research keywords (7)： Chlamydia trachomatis , Legionella pneumophila , Protozoa , bio-aerosol , Antimicrobial Resistant Bacteria , Veterinary Medicine , Bacteriology

Research theme for competitive and other funds (16)：

2022 - 2025 Functional elucidation of novel effectors of Legionella pneumophila approached through interactions with unique ciliate
2021 - 2025 New development of research to elucidate the intracellular adaptation mechanism of genital chlamydia unraveled from its similarity to cancer cells
2021 - 2024 次世代の耐性菌対策を考慮した、国際的ハイリスク病原性細菌の市中内定着様式の解明
2020 - 2024 Understanding and application of microbiota in building environment: creation of pathogen control theory by temperature control
2020 - 2024 入院患者の日常生活動作レベルがベッド周辺環境の微生物汚染に及ぼす影響

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Papers (82)：

Ruiyu Li, Saicheng Zhang, Satoko Otsuguro, Manabu Nagao, Akira Matsuda, Jeewan Thapa, Torahiko Okubo, Katsumi Maenaka, Hideaki Higashi, Hiroyuki Yamaguchi. Chlamydia trachomatis L2 434/Bu readily activates glycolysis under hypoxia for efficient metabolism. Biochemical and Biophysical Research Communications. 2024. 150461-150461
Hiroyuki Yamaguchi, Torahiko Okubo, Eriko Nozaki, Takako Osaki. Differential impact of environmental factors on airborne live bacteria and inorganic particles in an underground walkway. PloS one. 2024. 19. 3. e0300920
Steven Kakooza, Francis Mutebi, Paul Ssajjakambwe, Eddie Wampande, Esther Nabatta, Collins Atuheire, Sayaka Tsuchida, Torahiko Okubo, Kazunari Ushida, John Baligwamunsi Kaneene. Mastitis on selected farms in Wakiso district, Uganda: Burden, pathogens and predictors of infectivity of antimicrobial resistant bacteria in dairy herds. Veterinary medicine and science. 2023. 9. 5. 2376-2385
Saicheng Zhang, Yuki Funahashi, Satoho Tanaka, Torahiko Okubo, Jeewan Thapa, Shinji Nakamura, Hideaki Higashi, Hiroyuki Yamaguchi. Chlamydia trachomatis relies on the scavenger role of aryl hydrocarbon receptor with detyrosinated tubulin for its intracellular growth, but this is impaired by excess indole. Microbes and Infection. 2023. 25. 5. 105097-105097
Sayaka Tsuchida, Atsushi Ueda, Steven Kakooza, Torahiko Okubo, Eddie M Wampande, Takuji Yamada, Kazunari Ushida. The fecal microbiomes analysis of Marabou storks (Leptoptilos crumenifer) reveals their acclimatization to the feeding environment in the Kampala urban areas, Uganda. The Journal of veterinary medical science. 2023. 85. 4. 450-458

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MISC (12)：

ZHANG Saicheng, 大久保寅彦, 中村眞二, 東秀明, 山口博之. Pathogenic Chlamydia L2 requires aryl hydrocarbon receptors and detyrosinated tubulin for its growth. 日本細菌学雑誌(Web). 2023. 78. 1
大久保寅彦, 佐藤豊孝, 佐藤豊孝, 横田伸一, 中村眞二, 山口博之. Investigation of the mechanism of symbiotic bacteriadependent bacterial transport by amoebae. 日本細菌学雑誌(Web). 2022. 77. 1
佐藤豊孝, 立花徹, 玉井聡, 星野祐治, 鳥越慎吾, 榊原啓一郎, 前谷茂樹, 福田昭, 大久保寅彦, 臼井優, et al. One Health Approachに基づいたフルオロキノロン耐性大腸菌の市中内拡散・定着様式の解明. 日本獣医学会学術集会講演要旨集. 2022. 165th (CD-ROM)
榎枝秀朗, 田中菜那, 大久保寅彦, 佐藤豊孝, 横田伸一, THAPA Jeewan, 山口博之. Na+/H+ antiporter regulates desiccation tolerance in Escherichia coli. 日本細菌学雑誌(Web). 2021. 76. 1
田中菜那, 大久保寅彦, 佐藤豊孝, 横田伸一, THAPA Jeewan, 山口博之. Bacterial transport by amoeba that depend on symbiotic bacteria involves the Na⁺/H⁺ antiporter NhaA. 日本細菌学雑誌(Web). 2021. 76. 1

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Lectures and oral presentations (50)：

アメーバによる細菌運搬現象と Na+/H+ アンチポーターNhaA との関係性の検証
(第86回日本細菌学会北海道支部学術総会 2021)
Acanthamoeba S13WT relies on amoebal endosymbiont and bacterial NhaA for its ability to backpack bacteria on solid media.
(World Microbe Forum 2021 2021)
3D プリンターで作成したエアサンプラーによる空気中浮遊細菌の検出とその変動に関わる環境因子の探索
(第94回日本細菌学会総会 2021)
野外水系環境由来の繊毛虫存在下におけるLegionella pneumophilaの生存性の検討
(第93回日本細菌学会総会 2020)
イトトンボが保有する薬剤耐性菌の検出と分離菌株の性状解析
(第85回日本細菌学会北海道支部学術総会 2019)

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Education (3)：

2011 - 2015 Rakuno Gakuen University Graduate School Faculty of Veterinary Medicine Department of Veterinary Medicine
2005 - 2011 Rakuno Gakuen University Faculty of Veterinary Medicine Department of Veterinary Medicine
2002 - 2005 東京都立国立高等学校

Professional career (1)：

博士(獣医学) (酪農学園大学大学院)

Work history (2)：

2018/04 - 現在 Faculty of Health Sciences, Hokkaido University Department of Medical Laboratory Sciences Lecturer
2015/05 - 2018/03 Faculty of Health Sciences, Hokkaido University Department of Medical Laboratory Science Research associate

Awards (3)：

2017/08 - 第84回日本細菌学会北海道支部学術総会優秀賞札幌地下歩行空間での空気中浮遊細菌の菌叢解析
2016/09 - 第83回日本細菌学会北海道支部学術総会優秀賞北海道大学病院にて分離されたニューデリー・メタロβラクタマーゼNDM-5産生大腸菌の性状解析
2015/09 - 第82回日本細菌学会北海道支部学術総会最優秀賞繊毛虫との共培養で大腸菌から漏れ出すクオラムセンシング分子 autoinducer-2 について

Association Membership(s) (3)：

American Society for Microbiology , THE JAPANESE ASSOCIATION FOR INFECTIOUS DISEASES , JAPANESE SOCIETY FOR BACTERIOLOGY

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