Research theme for competitive and other funds (4):
2021 - 2024 Novel protecting strategy for the synthesis of fucosylated glycoproteins
2018 - 2020 ピコリン誘導体を利用したペプチド可溶化タグの創生
2016 - 2017 Ugi 反応を利用した簡便なペプチドチオエステル調整法の開発
2015 - 2016 Synthetic study of the O-glycoprotein using the solubilizing method
Papers (28):
Yasuhito Akai, Yuya Asahina, Hironobu Hojo. The dipicolylamino group as an efficient leaving group for amide bond formation via hexafluoroisopropyl ester. Organic & Biomolecular Chemistry. 2024
Yuhi Hosoe, Yohei Miyanoiri, Suyong Re, Saki Ochi, Yuya Asahina, Toru Kawakami, Masataka Kuroda, Kenji Mizuguchi, Masayuki Oda. Structural dynamics of the N-terminal SH2 domain of PI3K in its free and CD28-bound states. The FEBS Journal. 2022. 290. 9. 2366-2378
Yuya Asahina, Tatsuya Ando, Hironobu Hojo. Toward the Chemical Syntheses of Fucosylated Peptides: A Combination of Protecting Groups for the Hydroxy Groups of Fucose. Bulletin of the Chemical Society of Japan. 2022. 95. 8. 1196-1208
Shun Ito, Yuya Asahina, Hironobu Hojo. Investigation of protecting group for sialic acid carboxy moiety toward sialylglycopeptide synthesis by the TFA-labile protection strategy. Tetrahedron. 2021. 97. 132423-132423
Mikito Nakano, Shinya Hanashima, Toshiaki Hara, Kazuya Kabayama, Yuya Asahina, Hironobu Hojo, Naoko Komura, Hiromune Ando, Thomas K.M. Nyholm, J. Peter Slotte, et al. FRET detects lateral interaction between transmembrane domain of EGF receptor and ganglioside GM3 in lipid bilayers. Biochimica et Biophysica Acta (BBA) - Biomembranes. 2021. 1863. 8. 183623-183623
2022/10 - Japanese Peptide Society Young Investigator's Award Development of methodology for an efficient synthesis of glycoproteins
2019/08 - 日本糖質学会 第21回日本糖質学会ポスター賞
2016/10 - The Japanese Peptide Society Award for Excellence at Poster Presentation, 53rd Annual Meeting of JPS Study for Development of the one-pot ligation by using two orthogonal thioesterification devices
2011/11 - 日本ペプチド学会 JPS Travel Award
Association Membership(s) (3):
JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
, THE JAPANESE PEPTIDE SOCIETY
, THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH