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J-GLOBAL ID：201501045655894976 Update date: Apr. 10, 2025

Asahina Yuya

アサヒナユウヤ | Asahina Yuya

Affiliation and department：
Homepage URL (1)： https://www.lifescience.shokubai.co.jp/

Research field (1)： Bioorganic chemistry

Research keywords (4)： Glycoprotein , Peptide chemistry , Glycan , Organic synthesis

Research theme for competitive and other funds (4)：

2021 - 2024 Novel protecting strategy for the synthesis of fucosylated glycoproteins
2018 - 2020 Study of a novel peptide solubilizing tag based on picoline derivative
2016 - 2017 Ugi 反応を利用した簡便なペプチドチオエステル調整法の開発
2015 - 2016 Synthetic study of the O-glycoprotein using the solubilizing method

Papers (28)：

Yasuhito Akai, Yuya Asahina, Hironobu Hojo. The dipicolylamino group as an efficient leaving group for amide bond formation via hexafluoroisopropyl ester. Organic & Biomolecular Chemistry. 2024
Yuhi Hosoe, Yohei Miyanoiri, Suyong Re, Saki Ochi, Yuya Asahina, Toru Kawakami, Masataka Kuroda, Kenji Mizuguchi, Masayuki Oda. Structural dynamics of the N-terminal SH2 domain of PI3K in its free and CD28-bound states. The FEBS Journal. 2022. 290. 9. 2366-2378
Yuya Asahina, Tatsuya Ando, Hironobu Hojo. Toward the Chemical Syntheses of Fucosylated Peptides: A Combination of Protecting Groups for the Hydroxy Groups of Fucose. Bulletin of the Chemical Society of Japan. 2022. 95. 8. 1196-1208
Shun Ito, Yuya Asahina, Hironobu Hojo. Investigation of protecting group for sialic acid carboxy moiety toward sialylglycopeptide synthesis by the TFA-labile protection strategy. Tetrahedron. 2021. 97. 132423-132423
Mikito Nakano, Shinya Hanashima, Toshiaki Hara, Kazuya Kabayama, Yuya Asahina, Hironobu Hojo, Naoko Komura, Hiromune Ando, Thomas K.M. Nyholm, J. Peter Slotte, et al. FRET detects lateral interaction between transmembrane domain of EGF receptor and ganglioside GM3 in lipid bilayers. Biochimica et Biophysica Acta (BBA) - Biomembranes. 2021. 1863. 8. 183623-183623

MISC (17)：

仙波尚, 朝比奈雄也, 宇津木雅之, 堀本眞吾. Nippon Shokubai contributes to health and medicine through peptide drug manufacturing services from discovery to commercialization stage. Pharm Tech Japan. 2024. 40. 10
Nakano Mikito, Hanashima Shinya, Hara Toshiaki, Hara Toshiaki, Kabayama Kazuya, Asahina Yuya, Hojo Hironobu, Komura Naoko, Komura Naoko, Ando Hiromune, et al. FRET detects lateral interaction between transmembrane domain of EGF receptor and ganglioside GM3 in lipid bilayers. Biochimica et Biophysica Acta. 2021. 1863. 8
二村友香, 樺山一哉, 樺山一哉, 樺山一哉, 朝比奈雄也, 花島慎弥, 北條裕信, 深瀬浩一, 深瀬浩一, 深瀬浩一. Interaction analysis of transmembrane peptide of insulin receptor with ganglioside GM3. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
HOJO Hironobu, TAKEI Toshiki, ASAHINA Yuya, OKUMURA Nobuaki, TAKAO Toshifumi, SO Masatomo, SUETAKE Isao, SATO Takeshi, KAWAMOTO Akihiro, HIRABAYASHI Yoshio. CHEMICAL SYNTHESIS OF MEMBRANE PROTEIN CAVEOLIN AND ITS MEMBRANE INSERTION. ペプチド討論会講演要旨集. 2020. 57th
Yuka Nimura, Kazuya Kabayama, Yuya Asahina, Shinya Hanashima, Hironobu Hojo, Michio Murata, Koichi Fukase. Analysis of electrostatic interaction between ganglioside GM3 and transmembrane peptide. AIP Conference Proceedings. 2019. 2067

Committee career (2)：

Awards (4)：

2022/10 - Japanese Peptide Society Young Investigator's Award Development of methodology for an efficient synthesis of glycoproteins
2019/08 - 日本糖質学会第21回日本糖質学会ポスター賞
2016/10 - The Japanese Peptide Society Award for Excellence at Poster Presentation, 53rd Annual Meeting of JPS Study for Development of the one-pot ligation by using two orthogonal thioesterification devices
2011/11 - 日本ペプチド学会 JPS Travel Award

Association Membership(s) (3)：

JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY , THE JAPANESE PEPTIDE SOCIETY , THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH

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