Ishikawa Kei-ichi

イシカワケイイチ | Ishikawa Kei-ichi

Homepage URL (1)： https://kaken.nii.ac.jp/d/r/90733973.ja.html

Research field (1)： Neurology

Research keywords (2)：包括脳ネットワーク , Neurology

Research theme for competitive and other funds (13)：

2023 - 2026 パーキンソン病iPS細胞を用いたαシヌクレインによる自律神経病態の解明
2021 - 2024 患者iPS細胞表現型からの孤発性パーキンソン病の層別化と最適治療の開発
2020 - 2023 神経変性疾患由来iPS細胞を用いたin vitro血液脳関門モデル構築と病態解析
2020 - 2023 パーキンソン病iPS細胞を用いた老化脳環境モデル作製と病態解明
2018 - 2022 Identification of Parkinson's disease progression markers based on skeletal muscle-brain axis

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Papers (51)：

Zhiyang Yu, Shinji Saiki, Kenta Shiina, Tatou Iseki, Yukiko Sasazawa, Kei-Ichi Ishikawa, Noriko Nishikawa, Wataru Sako, Genko Oyama, Taku Hatano, et al. Comprehensive data for studying serum exosome microRNA transcriptome in Parkinson’s disease patients. Scientific Data. 2024. 11. 1
Daisuke Arai, Mikako Takahashi-Shibata, Takao Ukaji, Harumi Tsutsumi, Shori Tajima, Shin-ya Nishio, Kei-ichi Ishikawa, Wado Akamatsu, Fumihiko Matsumoto, Katsuhisa Ikeda, et al. Generation of an induced pluripotent stem cell line from a late-onset, progressive high frequency hearing loss patient due to mutation in CDH23. Stem Cell Research. 2024. 79. 103471-103471
Hayato Itoh, Masahiro Oda, Shinji Saiki, Koji Kamagata, Wataru Sako, Kei-ichi Ishikawa, Nobutaka Hattori, Shigeki Aoki, Kensaku Mori. Preliminary study of substantia nigra analysis by tensorial feature extraction. International Journal of Computer Assisted Radiology and Surgery. 2024
Xing Liu, Kei-ichi Ishikawa, Nobutaka Hattori, Wado Akamatsu. Generation of one induced pluripotent stem cell line JUCGRMi004-A from a Charcot-Marie-Tooth disease type 1A (CMT1A) patient with PMP22 duplication. Stem Cell Research. 2024
Tao Hu, Hayato Itoh, Masahiro Oda, Shinji Saiki, Nobutaka Hattori, Koji Kamagata, Wataru Sako, Kei-ichi Ishikawa, Shigeki Aoki, Kensaku Mori. Boosting substantia nigra segmentation from T2 weighted MRI via test-time normalization and distance-reweighted loss. Medical Imaging 2024: Computer-Aided Diagnosis. 2024

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MISC (76)：

Saiki Shinji, Shiina Kenta, Iseki Tatou, Yamashita Yuri, Takeshige Haruka, Kamo Hikaru, Ogawa Takashi, Yamashiro Kazuo, Ishikawa Kei-ichi, Taniguchi Daisuke, et al. パーキンソン病の運動症状とMRIパラメータに対するラサギリンの影響(Effects of rasagiline on motor symptoms and MRI parameters in Parkinson's disease). 臨床神経学. 2023. 63. Suppl. S229-S229
Yamaguchi Akihiro, Ishikawa Kei-ichi, Saiki Shinji, Hattori Nobutaka, Akamatsu Wado. 特発性パーキンソン病由来iPS細胞の表現型に基づく分類とその応用(Phenotype-based classification of idiopathic Parkinson's disease derived iPSCs and its application). 臨床神経学. 2023. 63. Suppl. S331-S331
山口昂大, 山口昂大, 石川景一, 石川景一, 石川景一, 斉木臣二, 服部信孝, 服部信孝, 服部信孝, 赤松和土. 孤発性パーキンソン病iPS細胞の表現型に基づく層別化とその応用. 日本再生医療学会総会(Web). 2023. 22nd
Yamaguchi Akihiro, Inage Mizuki, Ishikawa Kei-ichi, Schwamborn Jens, Hattori Nobutaka, Akamatsu Wado. パーキンソン病における中脳オルガノイド誘導と表現型解析(Midbrain organoid induction and phenotypic analysis in Parkinson's disease). 臨床神経学. 2022. 62. Suppl. S373-S373
Ishikawa Kei-ichi, Yamaguchi Akihiro, Saiki Shinji, Hattori Nobutaka, Akamatsu Wado. PD-iPSC由来の神経細胞の表現型と相関する臨床バイオマーカーの調査(Investigation of clinical biomarkers correlating with the phenotype of neurons derived from PD-iPSCs). 臨床神経学. 2022. 62. Suppl. S373-S373

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Patents (1)：

パーキンソン病診断指標

Lectures and oral presentations (41)：

特発性パーキンソン病由来iPS細胞の表現型に基づく分類とその応用(Phenotype-based classification of idiopathic Parkinson's disease derived iPSCs and its application)
(臨床神経学 2023)
パーキンソン病における中脳オルガノイド誘導と表現型解析(Midbrain organoid induction and phenotypic analysis in Parkinson's disease)
(臨床神経学 2022)
PD-iPSC由来の神経細胞の表現型と相関する臨床バイオマーカーの調査(Investigation of clinical biomarkers correlating with the phenotype of neurons derived from PD-iPSCs)
(臨床神経学 2022)
パーキンソン病iPS細胞を用いた病態解析・創薬スクリーニング
(日本再生医療学会総会(Web) 2019)
フィーダーフリー培養系iPS細胞を用いた中脳特異ドパミン作動性ニューロンの分化誘導法の検討
(日本再生医療学会総会(Web) 2019)

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Education (2)：

2010 - 2014 Juntendo University Graduate School of Medicine
1999 - 2005 Juntendo University Faculty of Medicine

Professional career (1)：

博士(医学)

Work history (11)：

2021/08 - 現在 Juntendo University Center for Genomic and Regenerative Medicine Associate professor
2021/08 - 現在 Juntendo University Department of Neurology Associate professor
2019/04 - 2021/07 Juntendo University Faculty of Medicine
2019/04 - 2021/07 Juntendo University Graduate School of Medicine
2020/09 - 2021/03 Newcastle University Visiting researcher

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Awards (2)：

2021 - the International Society for Stem Cell Research Stem Cell Reports Best of 2020-2021 Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease
2019/07 - the International Society for Stem Cell Research Merit Award iPSC-based drug screening for PARK9, a familial Parkinson’s disease with impaired autophagy

Association Membership(s) (6)：

International Society for Stem Cell Research , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , THE JAPANESE ASSOCIATION OF REHABILITATION MEDICINE , JAPAN SOCIETY FOR DEMENTIA RESEARCH , THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE , JAPANESE SOCIETY OF NEUROLOGY

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