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J-GLOBAL ID:201501052083494650   Update date: Sep. 08, 2024

Chikenji Takako S.

チケンジ タカコ | Chikenji Takako S.
Affiliation and department:
Job title: Professor
Homepage URL  (1): https://kaken.nii.ac.jp/d/r/40452982.ja.html
Research field  (4): Nutrition and health science ,  Anatomy ,  Orthopedics ,  Rehabilitation science
Research keywords  (7): Tissue regeneration ,  Cell senescence ,  Chronic inflammation ,  autoimmune disease ,  慢性腎臓病 ,  間葉系幹細胞 ,  Fibrosis
Research theme for competitive and other funds  (16):
  • 2024 - 2027 Elucidating the Pathophysiology of Rheumatoid Arthritis and Strategies for Joint Regeneration through the Mechanisms of Senescent Cell Fate Determination
  • 2023 - 2026 Elucidating the Divergence between Healthy Aging and Age-Related Diseases through Senescent-Origin Cells
  • 2024 - 2026 Revealing the pathomechanisms of rheumatoid arthritis through exploring the intercellular networks woven by senescent cells
  • 2023 - 2026 Understanding Stress-Resilient Cell-Cell Communications through Cellular Senescence
  • 2022 - 2025 老化細胞のメカノバイオロジー: メカニカルストレスによる細胞老化制御への挑戦
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Papers (39):
  • Yuki Saito, Sena Yamamoto, Takako S. Chikenji. Role of cellular senescence in inflammation and regeneration. Inflammation and Regeneration. 2024. 44. 1
  • Arisa Kita, Sena Yamamoto, Yuki Saito, Takako S. Chikenji. Cellular senescence and wound healing in aged and diabetic skin. Frontiers in Physiology. 2024. 15
  • Shogo Ijima, Yuki Saito, Sena Yamamoto, Kentaro Nagaoka, Taiki Iwamoto, Arisa Kita, Maki Miyajima, Tsukasa Sato, Akihiro Miyazaki, Takako S Chikenji. Senescence-associated secretory phenotypes in mesenchymal cells contribute to cytotoxic immune response in oral lichen planus. Immunity & ageing : I & A. 2023. 20. 1. 72-72
  • Yuki Saito, Maki Miyajima, Sena Yamamoto, Norihiro Miura, Tsukasa Sato, Arisa Kita, Shogo Ijima, Mineko Fujimiya, Takako S Chikenji. Intrathecal Injection of Mesenchymal Stromal Cell Cultured on 3D Fiber Ameliorates Multiple Organ Damage in Murine Lupus. Stem Cells Translational Medicine. 2022
  • Arisa Kita, Yuki Saito, Norihiro Miura, Maki Miyajima, Sena Yamamoto, Tsukasa Sato, Takatoshi Yotsuyanagi, Mineko Fujimiya, Takako S. Chikenji. Altered regulation of mesenchymal cell senescence in adipose tissue promotes pathological changes associated with diabetic wound healing. Communications Biology. 2022. 5. 1
more...
MISC (84):
  • 千見寺 貴子, 齋藤 悠城. 【老化を標的とした疾患予防・治療】老化細胞の光と影. 医学のあゆみ. 2023. 287. 5. 321-326
  • 齋藤 悠城, 千見寺 貴子. 骨格筋の再生と細胞老化. 基礎理学療法学. 2022. 25. 1. 61-68
  • 千見寺 貴子, 齋藤 悠城. 骨格筋における細胞老化と筋再生. 基礎老化研究. 2022. 46. 3. 8-8
  • 齋藤 悠城, 千見寺 貴子. 【健康寿命の鍵を握る骨格筋 代謝・内分泌を介した全身性制御の分子基盤から運動による抗老化まで】(第3章)個体の老化を支配する骨格筋の老化 運動による細胞老化制御と骨格筋再生. 実験医学. 2022. 40. 2. 222-228
  • 齋藤 悠城, 千見寺 貴子. 【健康寿命の鍵を握る骨格筋 代謝・内分泌を介した全身性制御の分子基盤から運動による抗老化まで】(第3章)個体の老化を支配する骨格筋の老化 運動による細胞老化制御と骨格筋再生. 実験医学. 2022. 40. 2. 222-228
more...
Patents (3):
  • 生体移植用細胞シート及びその製造方法
  • 間葉系幹細胞の賦活化剤への適応性を判定する方法
  • 間葉系幹細胞の賦活化剤、賦活化された間葉系幹細胞およびその製造方法
Lectures and oral presentations  (37):
  • Cellular senescence of synovial fibroblasts in rheumatoid arthritis model mice
    (An ASCB|EMBO meeting Cell Bio 2023 2023)
  • Cellular Senescence in Epidermal Stem Cells as a Potential Driver of Lupus Erythematosus Skin Lesions
    (An ASCB|EMBO meeting Cell Bio 2023 2023)
  • Exercise-induced senescence-like gene signature in fibro/adipogenic progenitors is impaired in diabetes muscle
    (An ASCB|EMBO meeting Cell Bio 2023 2023)
  • Involvement of Cellular Senescence in the Pathogenesis of Lupus Nephritis in Mice
    (An ASCB|EMBO meeting Cell Bio 2023 2023)
  • Identification of TGFB1-upregulated senescent fibroblasts in keloids
    (5th FHS International Conference 2023)
more...
Professional career (2):
  • Ph.D
  • 保健医療学博士
Work history (6):
  • 2021/04 - 現在 Hokkaido University Faculty of Health Sciences Professor
  • 2019/04 - 2021/03 Hokkaido University Associate professor
  • 2018/07 - 2019/06 Mayo Clinic Research fellow
  • 2014/10 - 2018/07 Sapporo Medical University School of Medicine Department of Anatomy Assistant professor
  • 2013/04 - 2014/09 Sapporo Medical University School of Health Sciences
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Awards (2):
  • 2020/06 - 北海道大学大学院保健科学研究院 優秀論文賞
  • 2020/02 - Orthopedics Research Society 2020 New Investigator Recognition Award (NIRA), Corresponding author
Association Membership(s) (7):
日本ハンドセラピィ学会 ,  JAPANESE ASSOCIATION OF OCCUPATIONAL THERAPISTS ,  JAPANESE SOCIETY FOR SURGERY OF THE HAND ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  International Cell Senescence Association ,  Orthopedic Research Society ,  日本炎症再生学会
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