Rchr
J-GLOBAL ID:201501060193540714
Update date: Oct. 17, 2024
TSUKIYAMA Tomoyuki
ツキヤマ トモユキ | TSUKIYAMA Tomoyuki
Affiliation and department:
Other affiliations (1):
Homepage URL (1):
https://ameblo.jp/regenerative-kyoto/
Research field (4):
Zoological sciences
, Animal production science
, Laboratory animal science
, Developmental biology
Research keywords (9):
遺伝子改変
, 大動物
, カニクイザル
, ゲノム編集
, Reproductive Biology
, Stem cells
, ES cells
, iPS cells
, reprogramming
Research theme for competitive and other funds (24):
- 2024 - 2030 ゲノム編集霊長類を用いた前頭葉機能とその障害の生成機構に関する研究開発
- 2023 - 2028 非ウイルス性トランスポゾンベクターを用いたトランスジェニックサルの作出
- 2022 - 2027 Elucidating the pathogenesis of and development of therapeutic strategies against the neuropsychiatric disorders in the primate models by utilizing the gene introduction and manipulation technologies
- 2024 - 2026 能動的組換えによる革新的遺伝子ノックイン
- 2024 - 2026 霊長類腎臓病学:霊長類モデルとヒト組織を用いた霊長類特異的腎障害修復機構の解明
- 2023 - 2026 Primate Nephrology: analyzing primate-specific repair mechanisms of renal injury
- 2021 - 2026 Spatio-temporal variabilities and robustness in pre-implantation mammalian development
- 2024 - 2025 遺伝子改変動物作出におけるモザイク性の解消
- 2024 - 2025 幹細胞を用いた羊膜前駆細胞の発生機序と細胞特性解析
- 2023 - 2025 Partial reprogramming of trophoblast stem cells to improve placental function
- 2022 - 2025 遺伝子改変動物作出におけるモザイク性の解消
- 2022 - 2025 幹細胞を用いた羊膜前駆細胞の発生機序と細胞特性解析
- 2022 - 2024 能動的遺伝子導入による革新的ノックイン技術の開発
- 2022 - 2023 能動的遺伝子導入による革新的ノックイン技術の開発
- 2020 - 2023 非ウイルス性トランスポゾンベクターを用いたトランスジェニックサルの作出
- 2020 - 2023 Establishment of a technology platform for genetic modification of fertilized eggs that enables analysis from the F0 generation
- 2020 - 2023 Cellular senescence of renal "subpopulations" influences renal aging and injury responsiveness
- 2020 - 2022 Development of innovative knock-in technology using endogenous homologous recombination mechanism
- 2019 - 2022 Development of diagnosis and therapy for aging using a nonhuman primate model of premature aging
- 2017 - 2022 Mechanism and Reconstitution In VItro of Human Germ Cell Development
- 2017 - 2020 Establishment of high-quality novel ES / iPS cells that precisely reflect the in vivo state
- 2015 - 2017 Establishment of novel pluripotent stem cells using genetically modified cynomolgus ES and iPS cells.
- 2013 - 2015 Establishment of novel pluripotent stem cells in mammals by iPS technology.
- 2009 - 2010 ES細胞由来タンパク質導入によるiPS細胞作製に関する研究
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Papers (40):
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Dimitri Fabrèges, Bernat Corominas-Murtra, Prachiti Moghe, Alison Kickuth, Takafumi Ichikawa, Chizuru Iwatani, Tomoyuki Tsukiyama, Nathalie Daniel, Julie Gering, Anniek Stokkermans, et al. Temporal variability and cell mechanics control robustness in mammalian embryogenesis. Science (New York, N.Y.). 2024. 386. 6718. eadh1145
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Keiko Yano-Sakamoto, Yuichiro Kitai, Naoya Toriu, Shinya Yamamoto, Ken Mizuta, Mitinori Saitou, Tomoyuki Tsukiyama, Ichiro Taniuchi, Motomi Osato, Motoko Yanagita. Expression pattern of Runt-related transcription factor (RUNX) family members and the role of RUNX1 during kidney development. Biochemical and biophysical research communications. 2024. 722. 150155-150155
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Shinichiro Oshima, Rahul Sinha, Kazuhiro Takeuchi, Ken Mizuta, Tomonori Nakamura, Ryoji Ito, Ikuo Kawamoto, Chizuru Iwatani, Masataka Nakaya, Hideaki Tsuchiya, et al. Atlas of Cynomolgus Macaque Hematopoiesis. 2024
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Satsuki Takashima, Eiichi Okamura, Yusuke Ichiyama, Kiyoto Nishi, Akio Shimizu, Chisato Watanabe, Masanaga Muto, Shoma Matsumoto, Setsuko Tsukiyama-Fujii, Tomoyuki Tsukiyama, et al. Null mutation of exocyst complex component 3-like does not affect vascular development in mice. Experimental animals. 2024. 73. 1. 93-100
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Akira Sato, Tomoyuki Tsukiyama, Masahiro Komeno, Chizuru Iwatani, Hideaki Tsuchiya, Ikuo Kawamoto, Mitsuru Murase, Takahiro Nakagawa, Iori Itagaki, Yasunari Seita, et al. Generation of a familial hypercholesterolemia model in non-human primate. Scientific reports. 2023. 13. 1. 15649-15649
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MISC (31):
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鳥生 直哉, 中家 雅隆, 山田 龍, 好川 貴久, 築山 智之, 柳田 素子, 伊佐 正. NPHP1ノックアウトカニクイザルの作成による若年性ネフロン癆の病態再現. 日本内科学会雑誌. 2023. 112. 臨増. 180-180
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高島さつき, 武藤真長, 渡部千里, 岡村永一, 松本翔馬, 築山智之, 藤井勢津子, 久保田慶顕, 水野聖哉, 杉山文博, et al. Exoc3l4 is essential for placental angiogenesis in mice. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
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小林憲市, 小林憲市, 築山智之, 中家雅隆, 依馬正次, 河内明宏. A MONKEY PKD1 MUTANT RECAPITULATES HUMAN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE. 日本小児泌尿器科学会雑誌. 2021. 30. 1
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小林 憲市, 築山 智之, 影山 進, 依馬 正次, 河内 明宏. 小児泌尿器科疾患:成育医療へのリレー 基礎研究が切り開く成育医療の未来. 日本泌尿器科学会総会. 2019. 107回. SY9-7
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Seita Yasunari, Tsukiyama Tomoyuki, Azami Takuya, Kobayashi Kenichi, IWATANI Chizuru, TSUCHIYA Hideaki, Nakaya Masataka, Tanabe Hideyuki, Hitoshi Seiji, Miyoshi Hiroyuki, et al. Comprehensive evaluation of ubiquitous promoters suitable for the generation of transgenic cynomolgus monkeys†. Biology of Reproduction. 2019
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Patents (1):
Books (1):
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マウス表現型解析スタンダード : 系統の選択、飼育環境、臓器・疾患別解析のフローチャートと実験例
羊土社 2016 ISBN:9784758101981
Education (4):
- 2008 - 2011 Kyoto University
- 2006 - 2008 Kyoto University
- 2002 - 2006 Kyoto University Faculty of Agriculture Faculty of Agriculture
- 1999 - 2002 洛南高等学校
Professional career (1):
Work history (7):
Committee career (1):
- 2020/04 - 2023/03 日本繁殖生物学会 若手奨励策検討委員
Awards (1):
- 2017/12 - 第34回滋賀医科大学シンポジウム 若鮎賞(最優秀賞)
Association Membership(s) (2):
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, SOCIETY FOR REPRODUCTION AND DEVELOPMENT
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