Rchr
J-GLOBAL ID:201501075174827260   Update date: Sep. 20, 2024

Maeda Kenji

Maeda Kenji
Affiliation and department:
Job title: Professor
Homepage URL  (2): https://ccvd.kufm.kagoshima-u.ac.jp/~antiviral/https://ccvd.kufm.kagoshima-u.ac.jp/~antiviral/eng/
Research field  (2): Virology ,  Infectious disease
Research keywords  (5): CMV ,  Antiviral therapy ,  SARS-CoV-2 ,  HBV ,  HIV-1
Research theme for competitive and other funds  (11):
  • 2017 - 2022 野生型と薬剤耐性B型肝炎ウイルスに強力な活性を発揮する新規治療薬の研究・開発
  • 2020 - 2022 HIV残存ウイルスリザーバーの評価を可能とする新規バイオマーカー探索と治療法開発
  • 2020 - 2021 新型コロナウイルス感染症(COVID-19)の治療法を確立するための研究
  • 2020 - 2021 COVID-19治療としての回復者血漿療法の基盤整備
  • 2018 - 2021 病態に即した個別化医療へ向けた抗HIV薬の薬物動態解析
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Papers (130):
  • Yoshiaki Yasutake, Shin-ichiro Hattori, Hiroki Kumamoto, Noriko Tamura, Kenji Maeda, Hiroaki Mitsuya. Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Scientific Reports. 2024. 14. 1
  • Takahiro Ishii, Takuya Kobayakawa, Kouki Matsuda, Kiyomi Nigorikawa, Peter Bolah, Airi Noborio, Kohei Tsuji, Nami Ohashi, Kazuhisa Yoshimura, Wataru Nomura, et al. Discovery of Potent DAG-Lactone Derivatives as HIV Latency Reversing Agents. ACS infectious diseases. 2024
  • Shogo Nakajima, Koichi Watashi, Takanobu Kato, Masamichi Muramatsu, Takaji Wakita, Noriko Tamura, Shin-Ichiro Hattori, Kenji Maeda, Hiroaki Mitsuya, Yoshiaki Yasutake, et al. Correction for Nakajima et al., "Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations". Journal of virology. 2024. 98. 3. e0182323
  • Peter J Halfmann, Kiyoko Iwatsuki-Horimoto, Makoto Kuroda, Yuichiro Hirata, Seiya Yamayoshi, Shun Iida, Ryuta Uraki, Mutsumi Ito, Hiroshi Ueki, Yuri Furusawa, et al. Characterization of Omicron BA.4.6, XBB, and BQ.1.1 subvariants in hamsters. Communications biology. 2024. 7. 1. 331-331
  • Kouki Matsuda, Kenji Maeda. HIV Reservoirs and Treatment Strategies toward Curing HIV Infection. International journal of molecular sciences. 2024. 25. 5
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MISC (16):
  • 安武義晃, 安武義晃, 服部真一朗, 田村範子, 松田幸樹, 向後悟, 前田賢次, 満屋裕明, 満屋裕明. Common structural basis for the resistance of reverse transcriptase against chirally distinct anti- HBV nucleoside analogues. 量子ビームサイエンスフェスタ(Web). 2021. 2020
  • Kouki Matsuda, Saiful Islam, Kiyoto Tsuchiya, Benjy Jek, Yang Tan, Shin-ichiro Hattori, Hiroo Katsuya, Paola Miyazato, Misaki Matsuo, Nicole S. Delino, et al. The WIPE assay for selection and elimination of HIV-1 provirus in vitro using latency-reversing agents. bioRxiv. 2019
  • 松田幸樹, 服部真一朗, 土屋亮人, 小早川拓也, 潟永博之, 吉村和久, 吉村和久, 吉村和久, 岡慎一, 遠藤泰之, et al. HIV再活性化に伴うアポトーシス誘導能を用いたHIVリザーバー除去に資する新たなShock&Kill療法の可能性. 日本エイズ学会誌. 2019. 21. 4
  • 安武義晃, 服部真一朗, 田村範子, 松田幸樹, 向後悟, 前田賢次, 満屋裕明, 満屋裕明. Structures of HBV-mimicking HIV-1 reverse transcriptase provides the basis of anti-HBV drug binding. 量子ビームサイエンスフェスタ(Web). 2019. 2018
  • Kenji Maeda, Debananda Das, Takuya Kobayakawa, Hirokazu Tamamura, Hiroaki Takeuchi. Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication. Current topics in medicinal chemistry. 2019. 19. 18. 1621-1649
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Professional career (2):
  • 医師
  • 医学博士
Work history (7):
  • 2022/04 - 現在 Kagoshima University Division of Antiviral Therapy, Joint Research Center for Human Retrovirus Infection Professor
  • 2015/04 - 2022/03 国立研究開発法人 国立国際医療研究センター 研究所 レトロウイルス感染症研究室長
  • 2013/01 - 2015/03 National Institutes of Health
  • 2010/01 - 2013/01 National Institutes of Health
  • 2005/01 - 2010/01 National Institutes of Health
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