Research field (3):
Biochemistry
, Chemical biology
, Molecular biochemistry
Research keywords (5):
Photopharmacology
, 光化学
, Medicinal chemistry
, Bioorganic Chemistry
, Chemical Biology
Research theme for competitive and other funds (9):
2022 - 2024 Development of photocaged reagents for specific persulfidation
2022 - 2024 Chemical construction of a photoreactive protein using a photopharmacological ligand
2019 - 2024 Principle of body malfunctioning through local cell division failure
2021 - 2023 Development of smart drugs for the sensing and inhibition of target biomolecules
2020 - 2022 Molecular movies for protein-ligand association and dissociation
2019 - 2021 Development of photocontrol techniques for cell division driven by motor proteins
2016 - 2018 Novel chemical protein labeling approach for analyzing the intracellular cargo transport system in kinesin
2014 - 2015 機能化DNA結合蛋白質による転写機構の解明と制御
2011 - 2013 自己集合を利用した酵素検出用19F-NMR/MRIオフオン型プローブの開発
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Papers (23):
Yu Watari, Kaito Nakatani, Kazuya Matsuo, Tomonori Waku, Akio Kobori. Wash-free FISH of bacterial ribosomal RNAs by benzo[a]pyrene-modified oligonucleotides. Results in Chemistry. 2024. 7. 101214-101214
Kazuya Matsuo, Shusuke Yamaoka, Tomonori Waku, Akio Kobori. In-cell chemical construction of a photoswitchable CENP-E using a photochromic covalent inhibitor. Organic & Biomolecular Chemistry. 2024. 22. 23. 4651-4655
Kazuya Matsuo, Ryota Uehara, Takashi Kikukawa, Tomonori Waku, Akio Kobori, Nobuyuki Tamaoki. Spatiotemporal regulation of CENP-E-guided chromosomes using a fast-relaxing arylazopyrazole photoswitch. Chemical Communications. 2024
Koya Yoshizawa, Akira Matsura, Masaya Shimada, Sumire Ishida-Ishihara, Fuyu Sato, Takahiro Yamamoto, Kan Yaguchi, Eiji Kawamoto, Taruho Kuroda, Kazuya Matsuo, et al. Tetraploidy-linked sensitization to CENP-E inhibition in human cells. Molecular Oncology. 2023. 17. 6. 1148-1166