Yamamoto Masamichi

ヤマモトマサミチ | Yamamoto Masamichi

Affiliation and department：
Homepage URL (1)： https://sites.google.com/view/yamamoto-laboratory/home

Research field (8)： Pathobiochemistry , Nephrology , Medical biochemistry , Clinical pharmacy , Physiology , Laboratory animal science , Neuroscience - general , Functional biochemistry

Research keywords (3)：イメージング , 代謝 , 発生学

Research theme for competitive and other funds (15)：

2022 - 2025 Energy metabolism in neuronal degeneration at the caudal site of spinal cord injury
2022 - 2025 Analysis of myocardial energy metabolism using an ATP visualization model in the progression of hereditary cardiomyopathy
2019 - 2023 Elucidation of channel synapse-mediated neurotransmission of tastes
2019 - 2023 Development of ultra-early diagnosis of dementia using technology to visualize homeostatic changes of all related organs
2019 - 2022 Development of quantitative measurement method of ATP production rate in mitochondria in mouse

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Papers (51)：

Shintaro Watanuki, Hiroshi Kobayashi, Yuki Sugiura, Masamichi Yamamoto, Daiki Karigane, Kohei Shiroshita, Yuriko Sorimachi, Takayuki Morikawa, Shinya Fujita, Kotaro Shide, et al. SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production. Cell stem cell. 2024
Shintaro Watanuki, Hiroshi Kobayashi, Yuki Sugiura, Masamichi Yamamoto, Daiki Karigane, Kohei Shiroshita, Yuriko Sorimachi, Shinya Fujita, Takayuki Morikawa, Shuhei Koide, et al. Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis. eLife. 2024. 12
Xiaoyu Song, Yuma Nihashi, Yukiko Imai, Nobuhito Mori, Noritaka Kagaya, Hikaru Suenaga, Kazuo Shin-ya, Masamichi Yamamoto, Daiki Setoyama, Yuya Kunisaki, et al. Collagen Lattice Model, Populated with Heterogeneous Cancer-Associated Fibroblasts, Facilitates Advanced Reconstruction of Pancreatic Cancer Microenvironment. International Journal of Molecular Sciences. 2024. 25. 7. 3740-3740
Xiaoyu Song, Yuma Nihashi, Masamichi Yamamoto, Daiki Setoyama, Yuya Kunisaki, Yasuyuki S. Kida. Exploring the Role of Desmoplastic Physical Stroma in Pancreatic Cancer Progression Using a Three-Dimensional Collagen Matrix Model. Bioengineering. 2023. 10. 12. 1437-1437
大西諭一郎, 竹中朋文, 山本正道. 神経損傷でのエネルギー代謝と軸索変性. 細胞. 2023. 55. 10. 846-849

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MISC (16)：

Yamamoto Masamichi, Ishihara Naotada. Frontiers and new trends in mitochondrial research: Dynamic behavior of key players in metabolic control, and its application to drug discovery. 2022. 94. 2. 157-158
Yamamoto Masamichi, Okamoto Yuki. Evaluation of mitochondrial energy production in vivo. 2022. 94. 2. 205-210
山本恵則, 高橋昌宏, 山本伸也, 山本正道, 柳田素子. 腎スライス培養を用いたATPイメージングによる各ネフロンセグメントのATP産生機構と腎毒性薬剤感受性の検討. 日本腎臓学会誌. 2020. 62. 4. 297-297
高橋昌宏, 山本恵則, 山本正道, 柳田素子. 生体内イメージングによる虚血再灌流障害におけるポドサイト細胞内ATP動態の解明. 日本腎臓学会誌. 2020. 62. 4. 346-346
山本恵則, 高橋昌宏, 山本伸也, 今村博臣, 山本正道, 柳田素子. 腎スライス培養を用いたATPイメージング系の樹立と各ネフロンセグメントにおけるATP産生機構の検討. 日本腎臓学会誌. 2019. 61. 3. 315-315

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Patents (3)：

生体内に局所的に外来物質を導入する方法、およびその利用
ATP可視化動物およびその用途
ATP動態測定に基づいた心毒性の判定方法

Professional career (1)：

博士(医学) (大阪大学)

Work history (1)：

2020/10 - 現在 National Cerebral and Cardiovascular Center, Research Institute

Awards (1)：

2019/11 - 日本認知症学会認知症学会奨励賞(基礎部門)

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