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J-GLOBAL ID:201601001735300237   Update date: Jan. 27, 2025

Takeda Haruna

タケダ ハルナ | Takeda Haruna
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Homepage URL  (1): https://kaken.nii.ac.jp/d/r/80647975.ja.html
Research field  (2): Pathobiochemistry ,  Tumor biology
Research keywords  (4): オルガノイド ,  大腸がん ,  トランスポゾン ,  マウス
Research theme for competitive and other funds  (7):
  • 2022 - 2028 大腸がんの転移機構の解明
  • 2021 - 2024 Identification and validation of colitis associated cancer driver genes.
  • 2020 - 2023 マウスモデルを用いた順遺伝学的手法による新規大腸がん治療標的の同定と機能検証
  • 2017 - 2021 Identification of colorectal cancer driver genes involved in cancer development and therapeutic resistance.
  • 2018 - 2019 トランスポゾンを用いたがん悪性化に関与するドライバー遺伝子の同定と機能検証
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Papers (20):
  • Akimi Yonezawa, Kana Shimomura, Koji Okamoto, Haruna Takeda. Inhibition of BRD4 attenuated IFNγ-induced apoptosis in colorectal cancer organoids. BMC cancer. 2025. 25. 1. 136-136
  • Naoko Iida, Yukari Muranaka, Jun Won Park, Shigeki Sekine, Neal G. Copeland, Nancy A. Jenkins, Yuichi Shiraishi, Masanobu Oshima, Haruna Takeda. Sleeping Beauty transposon mutagenesis in mouse intestinal organoids identifies genes involved in tumor progression and metastasis. Cancer Gene Therapy. 2024
  • Kana Shimomura, Naoko Hattori, Naoko Iida, Yukari Muranaka, Kotomi Sato, Yuichi Shiraishi, Yasuhito Arai, Natsuko Hama, Tatsuhiro Shibata, Daichi Narushima, et al. Sleeping Beauty transposon mutagenesis identified genes and pathways involved in inflammation-associated colon tumor development. Nature Communications. 2023. 14. 1
  • Kazuhiro Nishiyama, Hitomi Nishinakamura, Hideyuki Takeshima, Liu Yuyu, Chihiro Takeuchi, Naoko Hattori, Haruna Takeda, Satoshi Yamashita, Mika Wakabayashi, Kotomi Sato, et al. Mouse methylation profiles for leukocyte cell types, and estimation of leukocyte fractions in inflamed gastrointestinal DNA samples. PLOS ONE. 2023. 18. 10. e0290034-e0290034
  • 西山 和宏, 竹島 秀幸, 西中村 瞳, 服部 奈緒子, 竹内 千尋, 武田 はるな, 山下 聡, 小濱 和貴, 西川 博嘉, 牛島 俊和. 炎症を起こした消化管組織における白血球割合のマウスメチル化マーカーの確立. 日本消化器外科学会総会. 2023. 78回. P075-3
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Education (2):
  • 2001 - 2007 Kyoto University
  • 1997 - 2001 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
Work history (6):
  • 2024/04 - 現在 東京医科歯科大学 連携准教授
  • 2019/07 - 現在 国立がん研究センター 独立ユニット長
  • 2016/11 - 2019/06 Kanazawa University Cancer Research Institute
  • 2014/04 - 2016/10 Kanazawa Medical University School of Medicine
  • 2011/10 - 2014/03 The University of Tokyo
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Committee career (2):
  • 2023 - 現在 日本癌学会 評議員
  • 2021/11 - 2023/10 日本学術振興会科学研究費委員会専門委員
Association Membership(s) (3):
日本分子生物学学会 ,  American Association of Cancer Research ,  日本癌学会
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