Takeda Haruna

タケダハルナ | Takeda Haruna

Homepage URL (1)： https://kaken.nii.ac.jp/d/r/80647975.ja.html

Research field (2)： Pathobiochemistry , Tumor biology

Research keywords (4)：オルガノイド , 大腸がん , トランスポゾン , マウス

Research theme for competitive and other funds (7)：

2022 - 2028 大腸がんの転移機構の解明
2021 - 2024 Identification and validation of colitis associated cancer driver genes.
2020 - 2023 マウスモデルを用いた順遺伝学的手法による新規大腸がん治療標的の同定と機能検証
2017 - 2021 Identification of colorectal cancer driver genes involved in cancer development and therapeutic resistance.
2018 - 2019 トランスポゾンを用いたがん悪性化に関与するドライバー遺伝子の同定と機能検証

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Papers (19)：

Naoko Iida, Yukari Muranaka, Jun Won Park, Shigeki Sekine, Neal G. Copeland, Nancy A. Jenkins, Yuichi Shiraishi, Masanobu Oshima, Haruna Takeda. Sleeping Beauty transposon mutagenesis in mouse intestinal organoids identifies genes involved in tumor progression and metastasis. Cancer Gene Therapy. 2024
Kana Shimomura, Naoko Hattori, Naoko Iida, Yukari Muranaka, Kotomi Sato, Yuichi Shiraishi, Yasuhito Arai, Natsuko Hama, Tatsuhiro Shibata, Daichi Narushima, et al. Sleeping Beauty transposon mutagenesis identified genes and pathways involved in inflammation-associated colon tumor development. Nature Communications. 2023. 14. 1
Kazuhiro Nishiyama, Hitomi Nishinakamura, Hideyuki Takeshima, Liu Yuyu, Chihiro Takeuchi, Naoko Hattori, Haruna Takeda, Satoshi Yamashita, Mika Wakabayashi, Kotomi Sato, et al. Mouse methylation profiles for leukocyte cell types, and estimation of leukocyte fractions in inflamed gastrointestinal DNA samples. PLOS ONE. 2023. 18. 10. e0290034-e0290034
西山和宏, 竹島秀幸, 西中村瞳, 服部奈緒子, 竹内千尋, 武田はるな, 山下聡, 小濱和貴, 西川博嘉, 牛島俊和. 炎症を起こした消化管組織における白血球割合のマウスメチル化マーカーの確立. 日本消化器外科学会総会. 2023. 78回. P075-3
Daisuke Yamamoto, Hiroko Oshima, Dong Wang, Haruna Takeda, Kenji Kita, Xuelian Lei, Mizuho Nakayama, Kazuhiro Murakami, Takashi Ohama, Hirofumi Takemura, et al. Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer. The Journal of pathology. 2022. 257. 1. 39-52

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Education (2)：

2001 - 2007 Kyoto University
1997 - 2001 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy

Work history (6)：

2024/04 - 現在東京医科歯科大学連携准教授
2019/07 - 現在国立がん研究センター独立ユニット長
2016/11 - 2019/06 Kanazawa University Cancer Research Institute
2014/04 - 2016/10 Kanazawa Medical University School of Medicine
2011/10 - 2014/03 The University of Tokyo

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Committee career (2)：

2023 - 現在日本癌学会評議員
2021/11 - 2023/10 日本学術振興会科学研究費委員会専門委員

Association Membership(s) (3)：

日本分子生物学学会 , American Association of Cancer Research , 日本癌学会

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