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J-GLOBAL ID：201601002622284380   Update date: May. 21, 2024

Miyamoto Yoichi

ミヤモト ヨウイチ | Miyamoto Yoichi
Affiliation and department：
National Institutes of Biomedical Innovation, Health and Nutrition Center for Drug Design Research, Laboratory of Nuclear Transport Dynamics

About National Institutes of Biomedical Innovation, Health and Nutrition Center for Drug Design Research, Laboratory of Nuclear Transport Dynamics


Job title： Chief Researcher
Homepage URL  (1)： http://www.oka-lab.info/
Research field  (4)： Zoological sciences ,  Molecular biology ,  Medical biochemistry ,  Cell biology
Research keywords  (8)： 細胞核 ,  核タンパク質輸送 ,  Importin ,  ヌクレオポリン ,  感染症 ,  Spermatogenesis ,  Cancer ,  ストレス応答
Research theme for competitive and other funds  (15)：
  • 2024 - 2027 微小核の本態解明を目指したImportin-α1の新機能探索
  • 2022 - 2025 Exploring a novel function of nuclear transport molecules in male and female gametogenesis and elucidation of the infertility mechanism
  • 2020 - 2024 Elucidation of protein translation shutoff by mosquito-borne flavivirus
  • 2022 - 2024 フラビウイルス構成因子の核輸送機構の分子理解と創薬展開
  • 2020 - 2023 フラビウイルスの生活環に特異的な抗フラビウイルス薬の創出
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Papers (66)：
  • Koki Sakurai, Makiko Morita, Yoshiatsu Aomine, Mitsunobu Matsumoto, Tetsuji Moriyama, Emiko Kasahara, Atsuo Sekiyama, Mayumi Otani, Rieko Oshima, Kate L. Loveland, et al. Importin α4 deficiency induces psychiatric disorder-related behavioral deficits and neuroinflammation in mice. 2024
  • Hirotaka Nomiya, Koki Sakurai, Yoichi Miyamoto, Masahiro Oka, Yoshihiro Yoneda, Takatoshi Hikida, Masami Yamada. A Kpna1-deficient psychotropic drug-induced schizophrenia model mouse for studying gene-environment interactions. Scientific Reports. 2024. 14. 1
  • Masahiro Oka, Mayumi Otani, Yoichi Miyamoto, Rieko Oshima, Jun Adachi, Takeshi Tomonaga, Munehiro Asally, Yuya Nagaoka, Kaori Tanaka, Atsushi Toyoda, et al. Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure. Cell reports. 2023. 42. 8. 112884-112884
  • Jun Katahira, Tatsuya Ohmae, Mayo Yasugi, Ryosuke Sasaki, Yumi Itoh, Tomoko Kohda, Miki Hieda, Masami Yokota Hirai, Toru Okamoto, Yoichi Miyamoto. Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex. Nucleic acids research. 2023
  • Golam Iftakhar Khandakar, Yoichi Miyamoto, Ryosuke Satoh, Kenta Kishimoto, Mingzuo Xie, Mengyu Shih, Teruaki Takasaki, Genzoh Tanabe, Masahiro Oka, Reiko Sugiura. ACAGT-007a, an anti-cancer compound that modulates ERK MAPK signaling, induces nuclear enrichment of phosphorylated ERK in T3M4 pancreatic cancer cells. Genes to cells. 2023
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MISC (7)：
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Books (1)：
  • 決定版 阻害剤・活性化剤ハンドブック
    羊土社 2019
Education (3)：
  • 1997 - 2001 Osaka University
  • 1995 - 1997 Osaka University
  • 1991 - 1995 University of Miyazaki Faculty of Agriculture
Professional career (1)：
  • 博士(医学) (大阪大学)
Work history (10)：
  • 2024/04 - 現在 National Institutes of Biomedical Innovation, Health and Nutrition Laboratory of Biofunctional Molecular Medicine, Center for Drug Design Research Chief Research Scientist
  • 2023/04 - 2024/03 National Institutes of Biomedical Innovation, Health and Nutrition Laboratory of Nuclear Transport Dynamics, Center for Drug Design Research Chief Research Scientist
  • 2015/04 - 2023/03 National Institutes of Biomedical Innovation, Health and Nutrition Laboratory of Nuclear Transport Dynamics Sub-project leader
  • 2014/05 - 2015/03 National Institute of Biomedical Innovation Laboratory of Nuclear Transport Dynamics Sub-project leader
  • 2013/01 - 2014/04 Monash University Research Fellow
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Association Membership(s) (5)：
JAPAN SOCIETY FOR CELL BIOLOGY ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  日本癌学会 ,  日本医学教育学会
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