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J-GLOBAL ID：201601002622284380   Update date: Oct. 30, 2024

Miyamoto Yoichi

ミヤモト ヨウイチ | Miyamoto Yoichi
Affiliation and department：
National Institutes of Biomedical Innovation, Health and Nutrition Center for Drug Design Research, Laboratory of Biofunctional Molecular Medicine

About National Institutes of Biomedical Innovation, Health and Nutrition Center for Drug Design Research, Laboratory of Biofunctional Molecular Medicine


Job title： Chief Researcher
Research field  (4)： Zoological sciences ,  Molecular biology ,  Medical biochemistry ,  Cell biology
Research keywords  (8)： 細胞核 ,  核タンパク質輸送 ,  Importin ,  ヌクレオポリン ,  感染症 ,  Spermatogenesis ,  Cancer ,  ストレス応答
Research theme for competitive and other funds  (15)：
  • 2024 - 2027 微小核の本態解明を目指したImportin-α1の新機能探索
  • 2022 - 2025 Exploring a novel function of nuclear transport molecules in male and female gametogenesis and elucidation of the infertility mechanism
  • 2020 - 2024 Elucidation of protein translation shutoff by mosquito-borne flavivirus
  • 2022 - 2024 フラビウイルス構成因子の核輸送機構の分子理解と創薬展開
  • 2020 - 2023 フラビウイルスの生活環に特異的な抗フラビウイルス薬の創出
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Papers (69)：
  • Koki Sakurai, Makiko Morita, Yoshiatsu Aomine, Mitsunobu Matsumoto, Tetsuji Moriyama, Emiko Kasahara, Atsuo Sekiyama, Mayumi Otani, Rieko Oshima, Kate L Loveland, et al. Importin α4 deficiency induces psychiatric disorder-related behavioral deficits and neuroinflammation in mice. Translational psychiatry. 2024. 14. 1. 426-426
  • miR-147-3p in pathogenic CD4+ T cells controls chemokine receptor expression for the development of experimental autoimmune diseases. Journal of Autoimmunity. 2024. 149. 103319
  • Yumi Itoh, Yoichi Miyamoto, Makoto Tokunaga, Tatsuya Suzuki, Akira Takada, Akinori Ninomiya, Tomomi Hishinuma, Mami Matsuda, Yoshihiro Yoneda, Masahiro Oka, et al. Importin-7-dependent nuclear translocation of the Flavivirus core protein is required for infectious virus production. PLOS Pathogens. 2024. 20. 8. e1012409
  • Norifumi Iijima, Tomoya Hayashi, Masaaki Niino, Yoichi Miyamoto, Masahiro Oka, Ken J Ishii. Tridecylcyclohexane in incomplete Freund's adjuvant is a critical component in inducing experimental autoimmune diseases. European journal of immunology. 2024. e2350957
  • Hirotaka Nomiya, Koki Sakurai, Yoichi Miyamoto, Masahiro Oka, Yoshihiro Yoneda, Takatoshi Hikida, Masami Yamada. A Kpna1-deficient psychotropic drug-induced schizophrenia model mouse for studying gene-environment interactions. Scientific Reports. 2024. 14. 1
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MISC (7)：
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Books (1)：
  • 決定版 阻害剤・活性化剤ハンドブック
    羊土社 2019
Lectures and oral presentations  (29)：
  • A Novel Role of Importin α in the Micronucleus and Its Physiological Significance
    (15th International Conference on Nucleocytoplasmic Transport 2024)
  • 微小核における核輸送分子Importin-α1の新機能とがんにおける病態的意義
    (第83回日本癌学会学術総会 2024)
  • A novel function of the nuclear transport factor Importin α1 in the micronuclei.
    (2024)
  • Functional Significance of Importin Alpha in the Testis and Brain
    (The 27th North American Testis Workshop, Denver, Colorado 2024)
  • A novel functional aspect of Importin α in micronuclei
    (RIKEN International Symposium on Nuclear Structure and Function 2024 2024)
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Education (3)：
  • 1997 - 2001 Osaka University
  • 1995 - 1997 Osaka University
  • 1991 - 1995 University of Miyazaki Faculty of Agriculture
Professional career (1)：
  • 博士(医学) (大阪大学)
Work history (10)：
  • 2024/04 - 現在 National Institutes of Biomedical Innovation, Health and Nutrition Laboratory of Biofunctional Molecular Medicine, Center for Drug Design Research Chief Research Scientist
  • 2023/04 - 2024/03 National Institutes of Biomedical Innovation, Health and Nutrition Laboratory of Nuclear Transport Dynamics, Center for Drug Design Research Chief Research Scientist
  • 2015/04 - 2023/03 National Institutes of Biomedical Innovation, Health and Nutrition Laboratory of Nuclear Transport Dynamics Sub-project leader
  • 2014/05 - 2015/03 National Institute of Biomedical Innovation Laboratory of Nuclear Transport Dynamics Sub-project leader
  • 2013/01 - 2014/04 Monash University Research Fellow
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Association Membership(s) (4)：
JAPAN SOCIETY FOR CELL BIOLOGY ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  日本癌学会
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