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J-GLOBAL ID：201601004074190013 Update date: Mar. 05, 2025

Komba Shiro

コンバシロウ | Komba Shiro

Affiliation and department：
Job title： Principal Researcher
Homepage URL (2)： http://www.naro.affrc.go.jp/nfri-neo/index.html , http://www.naro.affrc.go.jp/english/nfri/index.html

Research field (1)： Bioorganic chemistry

Research keywords (2)： Oligosaccharide synthesis , 糖鎖合成

Research theme for competitive and other funds (12)：

2022 - 2025 Research on technology to promote digestion and absorption of anemia-related mineral and vitamin
2021 - 2025 Construction of Nanostructured Materials Using Cyclic Alcohol Derivatives, Control of Their Physical Properties, and Their Applications
2020 - 2023 デンプン系オイルゲルファイバー創製と機能発現
2019 - 2022 Creation and search of new fat-soluble vitamins
2016 - 2019 Study on intestinal absorption characteristics and nutrition/functionality of vitamin D

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Papers (60)：

Shiro Komba. Synthesis of D-glucono-1,4-lactones modified with linear saturated fatty acids as novel low molecular-weight organogelators and evaluation of their physical properties. Soft matter. 2025. 21. 10. 1970-1983
Rika Iwaura, Yoshihiro Kikkawa, Yoko Kawashima, Shiro Komba, Miyuki Kumano-Kuramochi, Mio Ohnuma, Iwao Sasaki. Insights into the mechanism of modification by self-assembling starch-based fatty acid esters that cause a pronounced time-dependent effect on asphalt hardness. Sustainable Materials and Technologies. 2024. 41. e01025-e01025
Sei Motouchi, Shiro Komba, Hiroyuki Nakai, Masahiro Nakajima. Discovery of Anomer-Inverting Transglycosylase: Cyclic Glucohexadecaose-Producing Enzyme from Xanthomonas, a Phytopathogen. Journal of the American Chemical Society. 2024. 146. 26. 17738-17746
Tomoya Ota, Wataru Saburi, Takayoshi Tagami, Jian Yu, Shiro Komba, Linda Elizabeth Jewell, Tom Hsiang, Ryozo Imai, Min Yao, Haruhide Mori. Molecular mechanism for endo-type action of glycoside hydrolase family 55 endo-β-1,3-glucanase on β1-3/1-6-glucan. Journal of Biological Chemistry. 2023. 299. 11. 105294-105294
Shiro Komba, Megumi Hase, Eiichi Kotake-Nara. Organic Synthesis of New Secosteroids from Fucosterol, Its Intestinal Absorption by Caco-2 Cells, and Simulation of the Biological Activities of Vitamin D. Marine Drugs. 2023. 21. 10. 540-540

MISC (78)：

太田智也, 佐分利亘, 山下恵太郎, 田上貴祥, 于健, 今場司朗, ジュウェルリンダ, シャントム, 今井亮三, 姚閔, et al. GH55β-1,3-グルカナーゼのエンド様式の作用と構造. 応用糖質科学. 2023. 13. 1
太田智也, 佐分利亘, 今場司朗, 森春英. Chemical synthesis of oligosaccharide with partial structure of β1-3/1-6 glucan. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
太田智也, 佐分利亘, 今場司朗, JEWELL Linda, HSIANG Tom, 今井亮三, 森春英. Laminarin degradation mechanism of GH55 laminarinase from Microdochium nivale. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
岩浦里愛, 今場司朗. Addition effects of 1,5-anhydroglucitol-based glycolipid with self-assembling ability on asphalt. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
今場司朗, 加治木隆仁, 岩浦里愛. オイルゲル化剤としての1,5-Anhydro-D-glucitol誘導体の合成. 応用糖質科学. 2022. 12. 3

Patents (8)：

Lectures and oral presentations (6)：

Development Of Low-Molecular-Mass Organo-Gelators Derived From Starch That Can Gel Various Oils At 1 Wt%
(The 31st International Carbohydrate Symposium 2024)
デンプン由来材料の添加によるアスファルトの性状変化
(第35回日本道路会議, 3153 2023)
食品展開を狙った澱粉由来オイルゲル化剤合成方法の開発
(日本応用糖質科学会2023年度大会, D1a-10 2023)
様々なオイルを1%でゲル化可能な澱粉由来オイルゲル化剤の開発
(第61回日本油化学会年会, PP26 2023)
澱粉由来の新規オイルゲル化剤の開発
(セミナー/おいしくてもヘルシー、乳化や結晶・ゲルの相転移で変わる新しい油脂の世界(日本調理食品研究会) 2022)

Professional career (1)：

Work history (5)：

2004/04 - 現在 National Agriculture and Food Research Organization
2002/03 - 2004/03 独立行政法人食品総合研究所酵素機能研究室重点研究領域特別研究員
1999/10 - 2002/02 RIKEN
1998/04 - 1999/09 Carlsberg Laboratory, Denmark Department of Chemistry
1995/12 - 1996/12 Virginia Commonwealth University, USA Department of Biochemistry and Molecular Biophysics

Awards (2)：

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