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J-GLOBAL ID：201601007711298191 Update date: Apr. 10, 2025

Niwa Tatsuya

ニワタツヤ | Niwa Tatsuya

Affiliation and department：

Research field (3)： Molecular biology , Biophysics , Structural biochemistry

Research theme for competitive and other funds (6)：

2024 - 2027 Development and application of a comprehensive method for proteome-wide protein conformational state analysis
2020 - 2023 無細胞タンパク質合成系とペプチドタグを利用したフォールディング進化系の確立
2017 - 2019 Influence of the change in the dynamics of the protein translation on the translation-coupled folding
2013 - 2015 Global aggregation analysis of eukaryotic proteins.
2012 - 2014 発現量の少ないタンパク質の凝集性とシャペロン要求性の解析

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Papers (65)：

Mayuka Hasumi, Hayato Ito, Kodai Machida, Tatsuya Niwa, Tomoya Taminato, Yoshitaka Nagai, Hiroaki Imataka, Hideki Taguchi. Dissecting the mechanism of NOP56 GGCCUG repeat-associated non-AUG translation using cell-free translation systems. Journal of Biological Chemistry. 2025
Yushin Ando, Akinao Kobo, Tatsuya Niwa, Ayako Yamakawa, Suzuna Konoma, Yuki Kobayashi, Osamu Nureki, Hideki Taguchi, Yuzuru Itoh, Yuhei Chadani. A mini-hairpin shaped nascent peptide blocks translation termination by a distinct mechanism. Nature Communications. 2025
Toma Ikeda, Tatsuya Nojima, Souma Yamamoto, Ryusei Yamada, Tatsuya Niwa, Hiroki Konno, Hideki Taguchi. Seesaw protein: Design of a protein that adopts interconvertible alternative functional conformations and its dynamics. Proceedings of the National Academy of Sciences of the United States of America. 2025. 122. 7. e2412117122
Yuishin Kosaka, Yumi Miyawaki, Megumi Mori, Shunsuke Aburaya, Chisato Nishizawa, Takeshi Chujo, Tatsuya Niwa, Takumi Miyazaki, Takashi Sugita, Mao Fukuyama, et al. Autonomous ribosome biogenesis in vitro. Nature Communications. 2025. 16. 1
Kazuki Miura, Hikaru Niimi, Tatsuya Niwa, Hideki Taguchi, Hiroyuki Nakamura. Intracellular Photocatalytic Proximity Labeling (iPPL) for Dynamic Analysis of Chromatin-Binding Proteins Targeting Histone H3. ACS chemical biology. 2024. 19. 12. 2412-2417

MISC (29)：

丹羽達也, 山川絢子, 茶谷悠平, 田口英樹. Development of a method to detect peptidyl-tRNA intermediates that reflect the dynamics of protein synthesis. 日本プロテオーム学会大会プログラム・抄録集. 2024. 2024 (Web)
茶谷悠平, 伊藤遥介, 丹羽達也, 丹羽達也, 山川絢子, 町田幸大, 今高寛晃, 田口英樹, 田口英樹. 蛋白質の合成過程に潜む途上終結リスクは生物のプロテオームに配列的制約をもたらす. 日本蛋白質科学会年会プログラム・要旨集. 2023. 23rd (CD-ROM)
茶谷悠平, 田邉葵, 丹羽達也, 田口英樹. 翻訳停滞とリボソーム不安定化による非典型的翻訳現象の駆動と再構成. 日本蛋白質科学会年会プログラム・要旨集. 2022. 22nd (Web)
丹羽達也, 茶谷悠平, 田口英樹. 定量プロテオミクスを用いた大腸菌GroE依存基質のGroE欠乏条件下における分解機構の解析. 日本蛋白質科学会年会プログラム・要旨集. 2022. 22nd (Web)
田邊葵, 茶谷悠平, 丹羽達也, 丹羽達也, 田口英樹, 田口英樹. 遺伝情報を拡張,再定義する非典型的翻訳の再構成. 日本遺伝学会大会プログラム・予稿集. 2022. 94th (CD-ROM)

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