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J-GLOBAL ID:201601008741364144   Update date: Apr. 07, 2025

Okuda Satoru

オクダ サトル | Okuda Satoru
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Affiliation and department:
Homepage URL  (2): http://mechgen.jphttp://mechgen.jp/index-en.html
Research field  (8): Developmental biology ,  Biological, health, and medical informatics ,  Structural and functional materials ,  Bio-, chemical, and soft-matter physics ,  Biomaterials ,  Biomedical engineering ,  Cell biology ,  Machine materials and mechanics
Research keywords  (18): 神経発生 ,  オルガノイド ,  細胞接着 ,  ゆらぎ ,  自己組織化 ,  集団運動 ,  細胞運動 ,  細胞骨格 ,  バーテックスモデル ,  幹細胞 ,  形態形成 ,  数理モデル ,  シミュレーション ,  ソフトマター ,  バイオメカニクス ,  器官形成 ,  メカノバイオロジー ,  生体力学
Research theme for competitive and other funds  (20):
  • 2024 - 2030 器官工作技術の開発と形態形成・進化メカニズムの解明
  • 2022 - 2027 Theoretical study of self-organization induced by mechanochemical feedback
  • 2024 - 2026 ECMが弾性を介して神経可塑性を制御する機構:新規AFMによる脳内の網羅計測
  • 2024 - 2026 3D力学動態モデリングによる細胞競合現象の理論的な理解
  • 2022 - 2025 核内の粘弾的特性がNanogの転写調節領域の空間的ゆらぎを制御する
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Papers (44):
  • Shuya Fukamachi, Razib Datta, Duligengaowa Wuergezhen, Takehiko Ichikawa, Rei Yagasaki, Shuhei A. Horiguchi, Phoebe Leeaw, Kohei Omachi, Aiko Sada, Itaru Imayoshi, et al. Epithelium Stratifies via Nucleation and Growth Induced by Foam-Geometric Instability. bioRxiv. 2024
  • Yan Chen, Nuria Taberner, Jason da Silva, Igor Kondrychyn, Nitish Aswani, Guihua Chen, Yasushi Okada, Anne Karine Lagendijk, Satoru Okuda, Li-Kun Phng. Circumferential actomyosin bundles drive endothelial cell deformations to constrict blood vessels. bioRxiv. 2024
  • Aki Teranishi, Misato Mori, Rihoko Ichiki, Satoshi Toda, Go Shioi, Satoru Okuda. An actin bracket-induced elastoplastic transition determines epithelial folding irreversibility. Nature Communications. 2024. 15. 10476
  • Narufumi Kameya, Itsuki Sakai, Kengo Saito, Toshihide Hamabe-Horiike, Yohei Shinmyo, Mitsutoshi Nakada, Satoru Okuda, Hiroshi Kawasaki. Evolutionary changes leading to efficient glymphatic circulation in the mammalian brain. Nature Communications. 2024. 15. 10048
  • Ken-ichi Tsubota, Shota Horikoshi, Tetsuya Hiraiwa, Satoru Okuda. Strain softening and hysteresis arising from 3D multicellular dynamics during long-term large deformation. bioRxiv. 2024
more...
MISC (9):
Patents (2):
Lectures and oral presentations  (79):
  • Elastoplastic transition: A Key Mechanism for Irreversible Epithelial Folding
    (2025 RIKEN BDR-CuSTOM Joint Organoid Symposium「Integrated organoid science: Stem cells, Engineering, Medicine」 2025)
  • Numerical simulation of a phase separation driven by cell polarity in epithelial sheet
    (Annual Meeting of the Physical Society of Taiwan 2025 2025)
  • Epithelial Mechanics Exhibiting a Switch-like Transition from Elastic to Plastic Folding
    (Annual Meeting of the Physical Society of Taiwan 2025 2025)
  • Epithelial stratification is phase transition driven by mechanical instability
    (Annual Meeting of the Physical Society of Taiwan 2025 2025)
  • 極性に駆動される細胞集団の相分離
    (第12回ソフトマター研究会 2024)
more...
Education (3):
  • 2010 - 2013 Kyoto University
  • 2008 - 2010 Kyoto University
  • 2004 - 2008 Kyoto University Faculty of Engineering
Professional career (1):
  • 博士(工学) (京都大学)
Work history (5):
  • 2019/04 - 現在 Kanazawa University Nano Life Science Institute Associate Professor
  • 2016/10 - 2020/03 Japan Science and Technology Agency (JST) PRESTO Researcher
  • 2016/04 - 2018/03 RIKEN Center for Developmental Biology (CDB) Special Postdoctoral Researcher
  • 2013/04 - 2016/03 RIKEN Center for Developmental Biology (CDB) Research Scientist
  • 2010/04 - 2013/03 Japan Society for the Promotion of Science Pre-Doctoral Fellow DC1
Awards (11):
  • 2024/04 - 文部科学省 文部科学大臣表彰 若手科学者賞 多細胞組織のアクティブな機械特性と力学動態に関する研究
  • 2022/11 - 化学とマイクロ・ナノシステム学会 優秀研究賞 マイクロ構造体上での組織変形を記述する粒子ベース力学モデルの開発
  • 2021/06 - 日本機械学会バイオエンジニアリング部門 瀬口賞
  • 2020/04 - 日本機械学会 日本機械学会賞(論文)
  • 2020/03 - さきがけ「統合1細胞解析のための革新的技術基盤」研究領域 ライジングスター賞
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Association Membership(s) (4):
JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS ,  THE BIOPHYSICAL SOCIETY OF JAPAN ,  THE JAPAN SOCIETY OF MECHANICAL ENGINEERS ,  日本神経科学学会
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