Research keywords (2):
Endocrinology
, Diabetology
Research theme for competitive and other funds (20):
2021 - 2024 抗糖尿病効果を発揮する熱ストレス応答経路の多臓器間クロストーク解明
2020 - 2023 胆汁酸トランスポーターを介した糖代謝・脂質代謝制御機構の解明と治療への応用
2017 - 2021 Mechanism of mineralocorticoid receptor-mediated regulation of GLP-1 secretion and chronic inflammation in pancreatic islet cells
2018 - 2021 抗糖尿病効果を発揮する熱ストレス応答経路活性化の臓器および分子間相互作用
2017 - 2020 Elucidation of the effects of anti-diabetes and anti-complications by activation of heat shock response pathway and translation for clinical application
2017 - 2020 The role of Skp2 in macrophage proliferation in atherosclerotic lesion
2017 - 2019 Identification and regulation of metalloproteinases involved in insulin resistance.
2016 - 2019 Inhibitory effect of TACE on WAT browning
2015 - 2018 ストレス応答活性化を介した抗糖尿病・抗炎症効果の分子機構解明
2013 - 2016 Shedding of TNF receptors in adipose tissues and insulin resistance
2012 - 2015 熱ショック応答経路の活性化による抗炎症効果の分子メカニズム解析
2011 - 2014 Molecular analysis of cell stress regulation by molecular chaperon and application for diabetes treatment
2011 - 2013 Involvement of mitochondrial ROS in the pathogenesis of diabetic complications
2010 - 2012 TNFa変換酵素を介したインスリン抵抗性発現機序の解析
2009 - 2011 Identification of novel molecules associated with insulin action or insulin secretion induced by mild electric current and hyperthermia therapy
2009 - 2011 Effect of cPLA_2 inhibition on the prevention of diabetic macrovascular complication
2008 - 2010 Development of novel treatment for type 2 diabetes by regulating cellular stresses targeted to molecular chaperone.
2007 - 2008 The inhibition of pancreatic b-cell deficiency and regenerationof β -cells by incretin signals
2006 - 2007 Regulation of insulin gene expression by small G protein related protein, Rho-kinase.
2004 - 2005 Analysis of the mechanisms of pancreatic β-cells destruction by intra-cellular oxidative stress and endoplasmic reticulum stress, and its application for the diabetes treatment.
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Papers (136):
Tatsuya Kondo, Takafumi Senokuchi, Jun Morinaga, Azusa Miyashita, Mayumi Yano, Haruo Takeda, Kenro Nishida, Naoto Kubota. The benefits and accuracy of real-time continuous glucose monitoring in children and adolescents with type 1 diabetes attending a summer camp. Journal of Diabetes Investigation. 2024
Tsugumasa Toma, Nobukazu Miyakawa, Yuiichi Arakaki, Takuro Watanabe, Ryosei Nakahara, Taha F S Ali, Tanima Biswas, Mikio Todaka, Tatsuya Kondo, Mikako Fujita, et al. An antifibrotic compound that ameliorates hyperglycaemia and fat accumulation in cell and HFD mouse models. Diabetologia. 2024
坊内良太郎, 坊内良太郎, 近藤龍也, 近藤龍也, 太田康晴, 太田康晴, 後藤温, 田中大祐, 佐藤博亮, 矢部大介, et al. A Consensus Statement from the Japan Diabetes Society: A Proposed Algorithm for Pharmacotherapy in People With Type 2 Diabetes (the Second Edition). 糖尿病(Web). 2023. 66. 10
近藤 龍也, 宮川 展和, 北野 さやか, 渡邊 拓郎, 吉積 臨太郎, Mary Ann Suico, 阪口 雅司, 井形 元維, 松村 剛, 甲斐 広文, et al. NAFLDの病態生理と治療における熱ストレス応答経路機構の役割-The role of heat shock response in the pathophysiology and treatment of NAFLD. 糖尿病・内分泌代謝科 = Diabetology, endocrinology & metabolology / 糖尿病・内分泌代謝科編集委員会 編. 2022. 55. 4. 499-507
Treatment with Mild electrical stimulation + heat shock (MET) suppresses the progression of atherosclerosis in ApoE deficient mice.
(American Diabetes Association 83rd Scientific Sessions 2023)
Characteristics of Type 2 Diabetes Mellitus in Japanese
(66th Japan Diabetes Society Meeting 2023)