Rchr
J-GLOBAL ID:201601009146057366
Update date: Aug. 23, 2024
Yamaguchi Shinpei
ヤマグチ シンペイ | Yamaguchi Shinpei
Affiliation and department:
Job title:
Lecturer
Homepage URL (2):
https://www.lab.toho-u.ac.jp/sci/bio/reprogramming/index.html
,
https://www.lab.toho-u.ac.jp/sci/bio/reprogramming/en/index.html
Research field (3):
Laboratory animal science
, Molecular biology
, Developmental biology
Research keywords (9):
リプログラミング
, DNAメチル化/脱メチル化
, 全能性
, 生殖細胞
, ゲノムインプリンティング
, ES細胞
, 初期胚
, エピジェネティクス
, 幹細胞
Research theme for competitive and other funds (6):
Papers (26):
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Takamasa Ito, Musashi Kubiura-Ichimaru, Fumihito Miura, Shoji Tajima, M. Azim Surani, Takashi Ito, Shinpei Yamaguchi, Masako Tada. DNMT1 can induce primary germ layer differentiation through de novo DNA methylation. Genes to Cells. 2024
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Tomoka Katayama, Marina Takechi, Yamato Murata, Yuta Chigi, Shinpei Yamaguchi, Daiji Okamura. Development of a chemically disclosed serum-free medium for mouse pluripotent stem cells. Frontiers in bioengineering and biotechnology. 2024. 12. 1390386-1390386
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Kit-Yeng Sheng, Toru Nakano, Shinpei Yamaguchi. A region-dependent allele-biased expression of Dopa decarboxylase in mouse brain. Frontiers in cell and developmental biology. 2022. 10. 1078927-1078927
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Maeda Takahiro, Yasuyoshi Kimura, Toru Nakano, Shinpei Yamaguchi. Ribosomal stress induces 2-cell embryo-like state transition of the mouse ESCs through p53 activation. Biochemical and biophysical research communications. 2021. 579. 175-180
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Yota Hagihara, Satoshi Asada, Takahiro Maeda, Toru Nakano, Shinpei Yamaguchi. Tet1 regulates epigenetic remodeling of the pericentromeric heterochromatin and chromocenter organization in DNA hypomethylated cells. PLoS genetics. 2021. 17. 6. e1009646
more...
MISC (15):
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Takahiro Maeda, Toru Nakano, Shinpei Yamaguchi. The physiological role and underlying mechanism of pericentric 5hmC in mouse primordial germ cell. MECHANISMS OF DEVELOPMENT. 2017. 145. S138-S138
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Shinpei Yamaguchi, Takahiro Maeda, Toru Nakano. Molecular function of Tet1 in the epigenetic reprogramming through mouse germ cell development. GENES & GENETIC SYSTEMS. 2016. 91. 6. 331-331
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Cheng Li-Tao, 長田翔伍, 平野邦生, 山口新平, 多田 高. マウスiPS 細胞におけるPkd1 遺伝子の遺伝的異常の 自発的正常化. 「第44 回日本発生生物学会総会」(2011.5.18-21. 那覇). 2011
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平野邦生, 長田翔伍, 山口新平, 中川 誠, 沖田圭介, 小寺秀俊, Justin Ainscough, 多田 高. リン酸化阻害剤 によるヒトとマウスiPS 細胞での異なるリプログラミング運命. 「第83 回日本遺伝学会総会」(2011.9.20-22, 京都). 2011
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Nagata S, Yamaguchi S, Hirano K, Tada T. Reprogramming-susceptible somatic cells and reprogrammingoptimized \nSox2 expression. 「Symposium; “Nuclear Reprogramming: From germline to cloned animals” in 43rd Annual Meeting for the Japanese Society of Developmental Bioilogists」(2010.6.21-23, Kyoto, JP)(Invited). 2010
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Books (2):
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誰でも再現できるNGS「前」サンプル調製プロトコール : 生物種別DNA、RNA、クロマチン、シングルセル調製の極意
羊土社 2024 ISBN:9784758122726
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エピジェネティクス実験スタンダード : もう悩まない!ゲノム機能制御の読み解き方
羊土社 2017 ISBN:9784758101998
Lectures and oral presentations (24):
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Stress-induced transition of mouse ESCs to a two-cell embryo-like state
(The 5th Open Symposium of the New Academic Research Area Totipotency Program 2023)
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Development of Tissue Cell Experimental Systems for Building Novel Drug Discovery Platforms
(12th Joint Seminar on Biomedical Sciences 2023)
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Understanding the Role of Genomic Imprinting: Exploring the physiological functions and molecular mechanisms in mice and stem cell models
(2023 Symposium on Epigenetic Regulation 2023)
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Epigenomes erased and imprinted in germ cells: regulatory mechanisms and functions.
(2023)
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マウス脳におけるインプリンティングの可視化と機能解明
(第45回日本分子生物学会年会 2022)
more...
Work history (6):
Awards (3):
- 2013/03 - Department of Genetics, Harvard Medical School Department of Genetics Retreat award at Retreat of Harvard Medical School
- 2013/03 - Best Poster award at Epigenetics & Chromatin Interactions and processes conference
- 2008/11 - 第23回内藤コンファレンス ベストポスター賞
Association Membership(s) (3):
日本分子生物学会
, 日本遺伝学会
, 日本エピジェネティクス研究会
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