2019 - 2022 Establishment of low-mosaic genome editing technology using plant DNA repair selection systems
2017 - 2021 「新奇ゲノム編集ツールの開発」
2016 - 2021 進化工学的および分子動力学的手法による新規ゲノム編集システムの創出
2017 - 2020 Investigation of molecular mechanism for switching from vegetative growth to sexual growth in mushroom forming fungi
2014 - 2019 ゲノム編集技術と開花促進技術の普及と高度化
2013 - 2018 Evolutionary and molecuar genetic studies to logics in plant development
2013 - 2016 Establishment of highly efficient chloroplast genome editing by using synthetic custom design nucleases
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Papers (100):
Pingping Ji, Osama A. Afifi, Senri Yamamoto, Yuriko Osakabe, Keishi Osakabe, Toshiaki Umezawa, Yuki Tobimatsu. Stacked mutations disrupting syringyl and p-coumaroylated lignin biosynthesis in rice result in lignin dominated by guaiacyl units: insights into grass-specific lignin monomer biosynthesis and polymerization mechanisms. 2025
Senri Yamamoto, Osama Ahmed Afifi, Lydia Pui Ying Lam, Yuri Takeda-Kimura, Yuriko Osakabe, Keishi Osakabe, Laura E. Bartley, Toshiaki Umezawa, Yuki Tobimatsu. Disruption of aldehyde dehydrogenase decreases cell wall-bound p-hydroxycinnamates and improves cell wall digestibility in rice. The Plant Journal. 2024
Supatmi, Lydia Pui Ying Lam, Senri Yamamoto, Osama A. Afifi, Pingping Ji, Yuriko Osakabe, Keishi Osakabe, Toshiaki Umezawa, Yuki Tobimatsu. Essential Yet Dispensable: The Role of CINNAMATE 4-HYDROXYLASE in Rice Cell Wall Lignification. bioRxiv (preprint). 2024
Masafumi Omori, Hisayo Yamane, Keishi Osakabe, Yuriko Osakabe, Ryutaro Tao. CRISPR-Cas9-mediated mutagenesis of the flowering repressor gene VcCENTRORADIALIS (VcCEN) induces early flowering in tetraploid highbush blueberry. 2024
Kohei Nakanishi, Hao Li, Takuji Ichino, Kanade Tatsumi, Keishi Osakabe, Bunta Watanabe, Koichiro Shimomura, Kazufumi Yazaki. Peroxisomal 4-coumaroyl-CoA ligases participate in shikonin production in Lithospermum erythrorhizon. Plant Physiology. 2024
“Crop Breeding Using CRISPR/Cas9”
“Crop Improvement Through Microbial Biotechnology” Elsevier 2018
“Genome editing to improve abiotic stress responses in plants”
“Gene Editing in Plants” Progress in Molecular Biology and Translational Science” Elsevier 2017
Current and future of genome engineering in agricultural products
(Bioengineering of lignocellulose for clean energy production: perspectives and opportunities, Univ. Kyoto 2019)
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, 日本ゲノム編集学会
, JAPANESE SOCIETY FOR PLANT BIOTECHNOLOGY
, THE JAPANESE SOCIETY OF PLANT PHYSIOLOGISTS
, The Society for Biotechnology, Japan
, The Botanical Society of Japan