2015 - 2018 Novel functions and relevance to the diseases of intracellular phospholipase A1
2015 - 2017 スフィンゴミエリン合成酵素のオリゴマー形成領域の同定と 機能解析
2012 - 2015 Research for the novel metabolic routes of endogenous marijuana-like substance, lysophosphatidylinosiol.
2013 - 2015 スフィンゴミエリン合成酵素を標的とした抗HIV剤の開発
2010 - 2012 内因性カンナビノイドを産生する新規ホスファチジルイノシトール代謝経路の解明
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Papers (44):
Takahiro Jomori, Nanami Higa, Shogo Hokama, Trianda Ayuning Tyas, Natsuki Matsuura, Yudai Ueda, Ryo Kimura, Sei Arizono, Nicole Joy de Voogd, Yasuhiro Hayashi, et al. A Novel Sesterterpenoid, Petrosaspongin and γ-Lactone Sesterterpenoids with Leishmanicidal Activity from Okinawan Marine Invertebrates. Marine Drugs. 2024. 23. 1. 16-16
Yasuhiro Hayashi, Takashi Tanikawa. Analysis of the Effects of Brefeldin A on Deuterium-Labeled Sphinganine Metabolism Using Liquid Chromatography-Tandem Mass Spectrometry. Biological and Pharmaceutical Bulletin. 2024. 47. 12. 2173-2181
Viqqi Kurnianda, Hao-Chun Hu, Ping-Jyun Sung, Yasuhiro Hayashi, Kanami Mori-Yasumoto, Ayumi Suetake, Hikari Nakayama, Mina Yasumoto-Hirose, Yuna Tsutsumi, Genta Koja, et al. Two isoledene-type sesquiterpenoids from a soft coral Heteroxenia sp. Tetrahedron Letters. 2024. 151. 155323-155323
Yoshio Kusakabe, Kazuya Matsumoto, Takahiro Tsuyuki, Yasuhiro Hayashi, Hideaki Watanabe. Baicalin target protein, Annexin A2, is a target of new antitumor drugs. Scientific Reports. 2024. 14. 1
Yasuhiro Hayashi, Takehiro Suzuki, Naoto Horioka, Naoshi Dohmae, Takashi Tanikawa. Phospholipid Scramblase 1 Localizes Proximal to Sphingomyelin Synthase Isoforms but Is Not Involved in Sphingomyelin Synthesis. Biological and Pharmaceutical Bulletin. 2024. 47. 6. 1136-1143
Sphingomyelin synthase 1 forms a complex with glucosylceramide synthase that is involved in the regulation of selective ceramide usage
(Gordon Research Conference, Galveston, USA (招待講演) 2018)
Carboxyl-terminal-mediated homodimerizations of sphingomyelin synthases are responsible for efficient ER export
(理化学研究所 脳科学総合研究センター研究会 (招待講演) 2016)
Education (3):
2004 - 2007 九州大学大学院 生物資源環境科学府 博士後期課程
2002 - 2004 九州大学大学院 生物資源環境科学府 修士課程
1998 - 2002 Kyushu University School of Agriculture
Professional career (1):
博士(農学) (九州大学)
Work history (5):
2022/01 - 現在 Miyazaki University Faculty of Agriculture
2020/04 - 2021/12 Teikyo University Faculty of Pharma-Science
2010/04 - 2020/03 Teikyo University Faculty of Pharma-Science
2008/04 - 2010/03 アメリカ国立衛生研究所 Visiting Fellow
2007/04 - 2008/03 九州大学大学院 CREST 研究員
Awards (2):
2007/09 - Poster Award, 48th International Conference on the Bioscience of Lipids "A novel catabolic pathway of glycosphingolipids mediated with a Klotho-related protein"
2006/08 - ポスター賞、 第26回 日本糖質学会年会 "Klotho related proteinはグルコセレブロシダーゼ活性を有する"
Association Membership(s) (3):
日本ウィルス学会
, THE JAPANESE CONFERENCE ON THE BIOCHEMISTRY OF LIPIDS
, THE JAPANESE BIOCHEMICAL SOCIETY