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J-GLOBAL ID:201601014578670062   Update date: Apr. 19, 2025

Mishima Yuichiro

ミシマ ユウイチロウ | Mishima Yuichiro
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Affiliation and department:
Homepage URL  (1): https://www.mishima-lab.com
Research field  (3): Systems genomics ,  Developmental biology ,  Molecular biology
Research keywords  (9): 受精 ,  tRNA ,  microRNA ,  コドン ,  mRNA分解 ,  翻訳 ,  Zebrafish ,  Development ,  RNA
Research theme for competitive and other funds  (22):
  • 2023 - 2026 リボソーム恒常性の乱れによって生じるmRNA特異的な翻訳変動の解明
  • 2022 - 2025 Tissue-specific regulation of translation initiation mediated by ribosome heterogeneity
  • 2022 - 2025 翻訳異常を解消するリボソーム品質管理機構の個体内イメージング
  • 2020 - 2024 Study of maternal-effect anemia caused by defective ribosome quality control
  • 2019 - 2021 自由自在な遺伝子発現を実現する転写ナノチップの創成
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Papers (25):
  • Kota Ishibashi, Yuichi Shichino, Peixun Han, Kimi Wakabayashi, Mari Mito, Toshifumi Inada, Seisuke Kimura, Shintaro Iwasaki, Yuichiro Mishima. Translation of zinc finger domains induces ribosome collision and Znf598-dependent mRNA decay in zebrafish. PLOS Biology. 2024. 22. 12. e3002887-e3002887
  • Xuewei Zhao, Ding Ma, Kensuke Ishiguro, Hironori Saito, Shinichiro Akichika, Ikuya Matsuzawa, Mari Mito, Toru Irie, Kota Ishibashi, Kimi Wakabayashi, et al. Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell. 2023
  • Nozomi Ugajin, Koshi Imami, Hiraku Takada, Yasushi Ishihama, Shinobu Chiba, Yuichiro Mishima. Znf598-mediated Rps10/eS10 ubiquitination contributes to the ribosome ubiquitination dynamics during zebrafish development. RNA. 2023. rna.079633.123-rna.079633.123
  • Junki Uchiyama, Rohini Roy, Dan Ohtan Wang, Kazuya Morikawa, Yuka Kawahara, Mio Iwasaki, Chiaki Yoshino, Yuichiro Mishima, Yasushi Ishihama, Koshi Imami. pSNAP: Proteome-wide analysis of elongating nascent polypeptide chains. iScience. 2022. 104516-104516
  • Yuichiro Mishima, Peixun Han, Kota Ishibashi, Seisuke Kimura, Shintaro Iwasaki. Ribosome slowdown triggers codon-mediated mRNA decay independently of ribosome quality control. The EMBO journal. 2022. 41. 5. e109256
more...
Books (10):
  • 動物の事典
    朝倉書店 2020 ISBN:9784254171662
  • 遺伝暗号による遺伝子発現制御
    生体の科学(医学書院) 2019
  • DOJIN BIOSCIENCEシリーズ「非コードRNA」
    化学同人 2016
  • 実験医学増刊号「ノンコーディングRNAテキストブック」
    羊土社 2015
  • microRNAはどのようにして標的mRNAを抑制するのか?
    実験医学増刊号(羊土社) 2013
more...
Education (3):
  • 2003 - 2006 Kobe University Graduate School of Science Ph.D., Department of Biology
  • 2001 - 2003 Nara Institute of Science and Technology M.Sc., Gradute School of Biological Sciences
  • 1997 - 2001 Osaka City University Faculty of Science B.Sc., Department of Biology
Professional career (1):
  • 博士(理学) (神戸大学)
Work history (8):
  • 2024/04 - 現在 Kyoto Sangyo University Faculty of Life Sciences Professor
  • 2019/04 - 2024/03 Kyoto Sangyo University Faculty of Lifesciences Associate Professor
  • 2018/04 - 2019/03 Kyoto Sangyo University Faculty of Lifesciences Associate Professor
  • 2012/10 - 2018/03 The University of Tokyo Institute of Molecular and Cellular Biosciences Research Assistant Professor
  • 2009/07 - 2012/09 Kobe University Department of Biology, Faculty of Science Post-doc
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Committee career (5):
  • 2025/04 - 現在 日本分子生物学会 キャリアパス委員(第24期)
  • 2020/04 - 2022/03 The RNA Society of Japan Accounting auditor
  • 2018/04 - 2020/03 日本RNA学会 キャリアパス担当委員
  • 2016/04 - 2018/03 東京大学 分子細胞生物学研究所 動物実験委員会 委員
  • 2013/04 - 2015/03 東京大学 分子細胞生物学研究所 広報誌編集委員会 委員
Awards (1):
  • 2017/04 - Ministry of Education, Culture, Sports, Science and Technology The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, The Young Scientists’ Prize "Molecular mechanisms of mRNA regulation during vertebrate early embryogenesis"
Association Membership(s) (2):
THE RNA SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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