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J-GLOBAL ID:201601015440785027   Update date: Apr. 11, 2025

Okunishi Katsuhide

オクニシ カツヒデ | Okunishi Katsuhide
Affiliation and department:
Job title: Professor
Homepage URL  (1): https://www.imcr.gunma-u.ac.jp/
Research field  (4): Pathobiochemistry ,  Allergies and connective tissue disease ,  Metabolism and endocrinology ,  Immunology
Research keywords  (5): アレルギー・喘息 ,  免疫 ,  内分泌・代謝 ,  生化学 ,  病態生理学
Research theme for competitive and other funds  (15):
  • 2023 - 2026 サイトカインを介した新奇肥満制御機構の解明
  • 2023 - 2024 アレルギーおよび肥満を制御する新奇分子基盤の解明
  • 2023 - 2024 GDF3-ALK7経路を介した肥満促進機構の分子基盤の解明
  • 2020 - 2023 Rab27によるアレルギー反応制御の分子基盤の解明
  • 2021 - 2022 Th2細胞の分化誘導を制御する新奇分子基盤の解明
Show all
Papers (49):
  • Min Zhao, Katsuhide Okunishi, Yun Bu, Osamu Kikuchi, Hao Wang, Tadahiro Kitamura, Tetsuro Izumi. Targeting activin receptor-like kinase 7 ameliorates adiposity and associated metabolic disorders. JCI insight. 2023. 8. 4
  • Kunli Zhao, Kohichi Matsunaga, Kouichi Mizuno, Hao Wang, Katsuhide Okunishi, Tetsuro Izumi. Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis. eLife. 2023. 12
  • Hao Wang, Kouichi Mizuno, Noriko Takahashi, Eri Kobayashi, Jun Shirakawa, Yasuo Terauchi, Haruo Kasai, Katsuhide Okunishi, Tetsuro Izumi. Melanophilin Accelerates Insulin Granule Fusion without Predocking to the Plasma Membrane. Diabetes. 2020. 69. 12. 2655-2666
  • Katsuhide Okunishi, Hao Wang, Maho Suzukawa, Ray Ishizaki, Eri Kobayashi, Miho Kihara, Takaya Abe, Jun-Ichi Miyazaki, Masafumi Horie, Akira Saito, et al. Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses. The Journal of clinical investigation. 2020. 130. 7. 3919-3935
  • Yun Bu, Katsuhide Okunishi, Satomi Yogosawa, Kouichi Mizuno, Maria Johnson Irudayam, Chester W Brown, Tetsuro Izumi. Insulin Regulates Lipolysis and Fat Mass by Upregulating Growth/Differentiation Factor 3 in Adipose Tissue Macrophages. Diabetes. 2018. 67. 9. 1761-1772
more...
MISC (33):
Books (6):
  • エキソフィリン-5 はIL-33 を介した Th2 応答の制御により アレルギー性気道炎症を調節する
    臨床免疫・アレルギー科(科学評論社) 2021
  • ALK7の肥満マウス白色脂肪織における生理的・病態生理的意義
    糖尿病・内分泌代謝科(科学評論社) 2020
  • Leukotrienes. Chapter#23 in Inflammation and Allergy Drug Design.
    Wiley-Blackwell. 2011
  • アレルギー科 20巻4号
    科学評論社 2005
  • SIRS の病態と治療 I ALI/ARDS
    医薬ジャーナル社 2004
more...
Lectures and oral presentations  (19):
  • Exophilin-5 regulates IL-33-mediated Th2 responses
    (The 15th International Symposium of the Institute Network for Biomedical Sciences 2020)
  • A novel regulatory role of the Rab27 effector exophilin5 in allergic airway inflammation
    (The 48th Annual Meeting of the Japanese Society for Immunology 2019)
  • Rab27エフェクターexophilin-5のアレルギー反応における役割
    (第68回日本アレルギー学会 2019)
  • インスリンを介した新奇脂肪蓄積機構の解明
    (第62回日本糖尿病学会 2019)
  • Adipose tissue macrophages promote adiposity by suppressing lipolysis in white adipocytes through activation of the GDF3-ALK7 axis
    (第46回日本免疫学会総会 2018)
more...
Education (3):
  • 2001 - 2005 The University of Tokyo
  • 1994 - 1998 The University of Tokyo Faculty of Medicine School of Medicine
  • 1992 - 1994 The University of Tokyo College of Arts and Sciences
Professional career (1):
  • M.D., Ph.D. (The University of Tokyo)
Work history (9):
  • 2025/04 - 現在 Toho University
  • 2020/07 - 2025/03 Gunma University Institute for Molecular and Cellular Regulation Department of Molecular Medicine Associate Professor
  • 2012/04 - 2020/06 Gunma University Institute for Molecular and Cellular Regulation Department of Molecular Medicine
  • 2008/05 - 2012/03 University of Michigan
  • 2005/04 - 2008/04 The University of Tokyo Faculty of Medicine
Show all
Awards (4):
  • 2022/09 - 群馬大学 創発支援研究
  • 2022/03 - 日本アレルギー学会 サノフィ優秀論文賞
  • 2021/02 - 群馬大学 論文奨励継続研究費
  • 2006 - Congress of the Asian Pacific Society of Respirology Excellent Presentation Awards
Association Membership(s) (6):
北関東医学会 ,  日本糖尿病学会 ,  日本肥満学会 ,  日本アレルギー学会 ,  日本免疫学会 ,  日本糖尿病・肥満動物学会
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