Research theme for competitive and other funds (4)：
2019 - 2022 Analysis of androgen-dependent gene expression of drug metabolizing enzymes using GHR-KO pigs
2016 - 2020 Genetic and pathophysiologic analyses of type 2 diabetes mellitus in newly established mouse model DDD-Ay
2013 - 2016 Development of a novel animal model of hepatocellular carcinoma with nonalcoholic steatohepatitis
2010 - 2012 Inhibitory effect of androgen on the constitutive gene expression of hepatic drug metabolizing enzymes and its mechanism
Papers (35)：
Misaki Kojima, Masakuni Degawa, Kiyomitsu Nemoto. Androgen-Dependent Expression of <i>CUX2</i> mRNA in the Pig Liver Is Associated with That of Drug Metabolizing Enzymes and Drug Transporters. Biological and Pharmaceutical Bulletin. 2023. 46. 3. 482-487
Misaki Kojima, Daiichiro Fuchimoto, Shiro Yamashita, Akira Onishi, Masakuni Degawa, Kiyomitsu Nemoto. Effect of Growth Hormone Receptor Deficiency on Androgen-Associated Gene Expression of Hepatic Drug Metabolizing Enzymes and Drug Transporters in Pigs. Biological & pharmaceutical bulletin. 2023. 46. 9. 1338-1342
Nakajima I, Kojima M, Oe M, Ojima K, Muroya S, Chikuni K. Comparing pig breeds with genetically low and high backfat thickness: differences in expression of adiponectin, its receptor, and blood metabolites. Domestic animal endocrinology. 2019. 68. 54-63
Kojima M, Nakajima I, Arakawa A, Mikawa S, Matsumoto T, Uenishi H, Nakamura Y, Taniguchi M. Differences in gene expression profiles for subcutaneous adipose, liver, and skeletal muscle tissues between Meishan and Landrace pigs with different backfat thicknesses. PloS one. 2018. 13. 9. e0204135
