Okumura Masaki

オクムラマサキ | Okumura Masaki

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://web.tohoku.ac.jp/okumura/

Research field (1)： Structural biochemistry

Research theme for competitive and other funds (44)：

Show all

Papers (53)：

Mikami R, Nishizawa Y, Iwata Y, Kanemura S, Okumura M,* and Arai K.*. ER Oxidoreductin 1-Like Activity of Cyclic Diselenides Drives Protein Disulfide Isomerase in an Electron Relay System. ChemBioChem. 2024. in press
Honoka Kawamukai, Motonori Matsusaki, Takanari Tanimoto, Mai Watabe, Ken Morishima, Shunsuke Tomita, Yoichi Shinkai, Tatsuya Niwa, Taro Mannen, Hiroyuki Kumeta, et al. Conserved loop of a phase modifier endows protein condensates with fluidity. 2024
Suzuki K, Nojiri R, Matsusaki M, Mabuchi T, Kanemura S, Ishii K, Kumeta H, Okumura M,* Saio T, * and Muraoka T.*. Redox-active chemical chaperones exhibiting promiscuous binding promote oxidative protein folding under condensed sub-millimolar conditions. Chem. Sci. 2024. 29. 12676-12685
T. Kuramochi, Y. Yamashita, K. Arai, S. Kanemura, T. Muraoka, M. Okumura. Boosting the enzymatic activity of CxxC motif-containing PDI family members. 2024. 60. 6134-6137★Inside front coverに選出されました
Muraoka T,* Okumura M,* and Saio T.*. Enzymatic and synthetic regulation of polypeptide folding. Chem. Sci. 2024. 15. 2282-2299

ｍore...

MISC (3)：

Young-Ho Lee, Tomohide Saio, Mai Watabe, Motonori Matsusaki, Shingo Kanemura, Yuxi Lin, Taro Mannen, Tsubura Kuramochi, Katsuya Iuchi, Michiko Tajiri, et al. Ca²⁺-driven PDIA6 phase separation to ensure proinsulin quality control. 2024
Masaki Okumura, Tsubura Kuramochi, Yuxi Lin, Ran Furukawa, Kenji Mizutani, Takeshi Yokoyama, Mingeun Kim, Mi Hee Lim, Hyon-Seung Yi, Kenta Arai, et al. Dose-response relationship for the resistance of human insulin to degradation by insulin-degrading enzyme. BioRxiv. 2023
Jeong, H, Lin, Y, Kim, J.H, Yu, W, Heo, Y, Won, H.S, Okumura, M, Lee, Y.H*. Atomistic structure of the interlocking claw-like amyloid fibril of full-length glucagon. BioRxiv. 2022

Patents (7)：

ｍore...

Books (14)：

2024 Joint Conference - Korean Society for Protein Science & Protein Science Society of Japanの開催報告
日本蛋白質科学会ニュースレター Vol. 24, No. 10 (2024) 2024
生物学的相分離の多元的理解~屈折率表示を例に~
月刊細胞特集「LC(Low-Complexity)ドメインの生物学」 2023
小胞体ジスルフィド結合触媒ネットワークを支える酵素群の構造基盤
日本結晶学会誌64,209-210 2022
小胞体におけるMHCの品質管理
臨床免疫・アレルギー科 74 (5) 1-8 2020
高速原子間力顕微鏡により明らかにされたプロテインジスルフィドイソメラーゼ(PDI)の構造ダイナミクス
生化学、pp107-112 2020

ｍore...

Lectures and oral presentations (207)：

神経変性疾患の治療に向けたシャペロンの化学制御
(分子生物学会 2024)
Elucidating the enzymatic reductive unfolding mechanism of spike/envelope proteins to guide anti-virus activities
(2024)
Discovery of protein quality control granule formed by both Ca2+ and PDIA6
(UCSF seminar US 2024)
小胞体内タンパク質品質管理に関わる新たな区画の理解
(第97回生化学会 2024)
Ca2+-driven protein quality control granule formation to ensure proinsulin folding fidelity
(EMBO meeting on The endoplasmic reticulum - guardian of cellular homeostasis 2024)

ｍore...

Education (2)：

Professional career (1)：

Work history (9)：

2022/04 - 現在東北大学生命科学研究科 (兼務)
2022/04 - 現在東北大学学際科学フロンティア研究所准教授
2021/07 - 現在東北大学プロミネントリサーチフェロー
2017/04 - 2022/03 Tohoku University Frontier Research Institute for Interdisciplinary Sciences
2016/04 - 2017/03 Tohoku University Institute of Multidisciplinary Research for Advanced Materials

Show all

Awards (6)：

Show all

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page