Rchr
J-GLOBAL ID:201601018340670671
Update date: May. 02, 2024
Katoh Toshihiko
カトウ トシヒコ | Katoh Toshihiko
Affiliation and department:
Research field (2):
Functional biochemistry
, Applied microbiology
Research keywords (6):
Bifidobacterium
, グライコミクス
, グリコシダーゼ
, 腸内細菌
, 糖鎖生物学
, 応用微生物学
Research theme for competitive and other funds (18):
- 2024 - 2026 糖鎖結合プローブの開発と応用による宿主と腸内細菌の相互作用の解明
- 2023 - 2026 Elucidation of mechanisms for human-microbiome symbiosis mediated by the sulfated mucin glycan-terminal structures
- 2022 - 2025 Molecular mechanism and its physiological significance of metal coordination in Tyrosinase family proteins
- 2024 - 2025 ムチンO-グライコームと腸内細菌の相関解析
- 2022 - 2024 Bifidobacterium bifidum糖質分解酵素によるムチン糖鎖コア切り分けの分子メカニズムの解明
- 2022 - 2023 Construction of an enzymatic toolkit for de-glycosylation of mucin using bacterial glycosidases
- 2019 - 2022 Functional analysis and application of sulfoglycosidase from mucin-assimilating bacteria
- 2019 - 2021 Physiological role of bifidus flora formation in breast-fed infant guts
- 2018 - 2021 Development of an in vitro co-culture system for elucidation of host-gut microbiota symbiotsis
- 2020 - 2021 卵白オボムチンの腸内ムチン分解菌増殖効果
- 2019 - 2020 ムチン研究ツールとしてのビフィズス菌糖質分解酵素群に関する研究
- 2017 - 2019 Host-microbe symbiosis mediated through symbiogenic factors
- 2017 - 2019 Functional analysis and application studies of gut microbe-derived sulfoglycosidase and sulfated mucin in symbiosis
- 2016 - 2019 Innovative technique for production of biomedicines with uniform sugar chains by use of microbial enzymes
- 2017 - 2018 均質なバイオ医薬品の生産を志向した微生物エンド型グリコシターゼの改変
- 2015 - 2017 ビフィズス菌がヒト腸内に定着するために重要なスルファターゼ遺伝子の役割の解析
- 2013 - 2016 Development of the innovative technique for addition of sugar chain using microbial enzymes and its application on the syntheses of functional glycoconjugates
- 2003 - 2005 線虫由来の糖鎖分解酵素の生理機能の解明と糖鎖の代謝機構の解析に関する研究
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Papers (49):
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Toshihiko Katoh, Hisashi Ashida. Bacterial Enzyme Assay for Mucin Glycan Degradation. Methods in Molecular Biology. 2024. 337-344
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Hiromi Takada, Takane Katayama, Toshihiko Katoh. Cultivation of Microorganisms in Media Supplemented with Mucin Glycoproteins. Methods in Molecular Biology. 2024. 331-335
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Toshihiko Katoh, Takane Katayama. Mucin Decomposition Mechanisms in Gut Bacteria. Glycoforum. 2024. 27. 1. A3
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Ayumi Mure, Yuki Sugiura, Rae Maeda, Kohei Honda, Nozomu Sakurai, Yuuki Takahashi, Masayoshi Watada, Toshihiko Katoh, Aina Gotoh, Yasuhiro Gotoh, et al. Identification of Core Yeast Species and Microbe-Microbe Interactions Impacting Larval Growth ofDrosophilain the Wild. 2023
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Hiromi Takada, Toshihiko Katoh, Mikiyasu Sakanaka, Toshitaka Odamaki, Takane Katayama. GH20 and GH84 β-N-acetylglucosaminidases with different linkage specificities underpin mucin O-glycan breakdown capability of Bifidobacterium bifidum. Journal of Biological Chemistry. 2023. 104781-104781
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MISC (30):
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Toma Kashima, Toshihiko Katoh, Chihaya Yamada, Takane Katayama, Hisashi Ashida, Shinya Fushinobu. 【総説:応用糖質科学シンポジウム】<i>Bifidobacterium bifidum</i>由来の硫酸化ムチン糖鎖および血液型抗原分解酵素の構造基盤. Bulletin of Applied Glycoscience. 2023. 13. 4. 194-202
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CHOI Moonhak, 後藤愛那, 阪中幹祥, 加藤紀彦, 西本完, 杉山友太, 栗原新, 吹谷智, 横田篤, 北岡本光, et al. Mucin O-glycan assimilation pathway in Bifidobacterium. 日本農芸化学会大会講演要旨集(Web). 2021. 2021
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阪中幹祥, 阪中幹祥, 栗原新, 栗原新, 片山高嶺, 片山高嶺, HANSEN Morten Ejby, 後藤愛那, 加藤紀彦, 吉田圭佑, et al. Evolutionary traits found in fucosyllactose transporters support symbiosis between bifidobacteria and breast-fed infants. Institute for Fermentation, Osaka. Research Communications. 2019. 33
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後藤愛那, 後藤愛那, 阪中幹祥, 阪中幹祥, 片山高嶺, 片山高嶺, 栗原新, 栗原新, 杉山友太, 奈良未沙希, et al. Use of Gifu Anaerobic Medium for culturing 32 dominant species of human gut microbes and its evaluation based on short-chain fatty acids fermentation profiles. Institute for Fermentation, Osaka. Research Communications. 2019. 33
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阪中 幹祥, 砂川 直輝, 佐藤 真与, 吉田 圭佑, 石田 卓也, 後藤 愛那, 加藤 紀彦, 谷内 寛之, 密山 恵梨, 加藤 久美子, et al. ビフィズス菌におけるラクト-N-テトラオース輸送体の同定およびビフィズスフローラ形成への関与. 腸内細菌学雑誌. 2018. 32. 2. 101-101
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Books (3):
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中分子創薬に資するペプチド・核酸・糖鎖の合成技術
シーエムシー出版 2018
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Glycoscience : biology and medicine
Springer 2015 ISBN:9784431548409
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Comprehensive glycoscience : from chemistry to systems biology
Elsevier 2007 ISBN:9780444527462
Lectures and oral presentations (27):
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硫酸化ムチン糖鎖の分解に関わる腸内細菌由来酵素の解析
(糖質関連酵素研究の若手シンポジウム 2024)
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A sulfoglycosidase from Bifidobacterium bifidum is involved in the degradation of sulfated mucin O-glycans in the intestine
(SfG-2023 Annual Meeting 2023)
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腸内細菌の硫酸化ムチン糖鎖資化戦略-ビフィズス菌を例に-
(日本応用糖質科学会2023年度大会(第72回)応用糖質科学シンポジウム 2023)
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腸内細菌由来スルフォグリコシダーゼによる 腸管内でのムチン糖鎖分解
(第42会日本糖質学会 2023)
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Bifidobacterium bifidum Degrades Sulfated Mucin O-Glycans Via a Sulfatase-independent Pathway
(GLYCO26 Taiwan 2023)
more...
Education (3):
- 2003 - 2007 Kyoto University Graduate School of Biostudies
- 2001 - 2003 Kyoto University Graduate School of Biostudies
- 1997 - 2001 Kyoto University Faculty of Agriculture
Professional career (1):
Work history (4):
- 2023/05 - 現在 Kyoto University Graduate School of Biostudies Associate Professor
- 2015/10 - 2023/04 Kyoto University Graduate School of Biostudies
- 2013/10 - 2015/09 Ishikawa Prefectural University
- 2007/11 - 2013/09 University of Georgia
Committee career (1):
- 2021/07 - 2023/06 日本応用糖質科学会近畿支部 常任幹事
Awards (2):
- 2023/06 - 天野エンザイム科学技術振興財団 第24回酵素応用シンポジウム研究奨励賞 腸内細菌による硫酸化ムチン糖鎖の新規分解経路の解明
- 2021 - 日本応用糖質科学会 奨励賞 ムチン糖鎖の構造的・機能的多様性の解析と微生物酵素の応用による糖鎖合成研究
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