Research field (2):
Pathobiochemistry
, Metabolism and endocrinology
Research keywords (1):
肝臓
Research theme for competitive and other funds (7):
2022 - 2027 Homeostatic regulation of amino acid metabolism through the viewpoint of glucagon and liver zonation.
2021 - 2024 膵内分泌腫瘍モデルマウスを用いたアミノ酸代謝異常を介した発がん機構の解明
2017 - 2020 Elucidation of the effect of variants in the PCSK9 gene and molecular type on lifestyle-related diseases and its regulatory mechanism
2019 - 2019 アキレス腱の軟らかさに着目した家族性高コレステロール血症・新診断法の確立
2015 - 2017 Involvement of the type of PCSK9 in familial hypercholesterolemia, obesity and diabetes
2012 - 2015 The effect of neuromedin U to atherosclerosis caused by chronic inflammation
2007 - 2008 dGTPの酸化損傷体の生細胞における変異誘発とその防御機構の解明
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Papers (72):
Sayaka Funabashi, Yu Kataoka, Mika Hori, Masatsune Ogura, Takahito Doi, Yoshiaki Morita, Eri Kiyoshige, Kunihiro Nishimura, Teruo Noguchi, Mariko Harada-Shiba. Asymptomatic Intracranial Artery Stenosis/Occlusion in Heterozygous Familial Hypercholesterolemia: Its Frequency and Implications for Cerebrovascular and Cardiovascular Events. Journal of the American Heart Association. 2024. 13. 15. e033972
Kotaro Noda, Yorito Hattori, Mika Hori, Mariko Harada-Shiba, Masafumi Ihara. A Case of Multiple Intracranial Major Artery Stenoses With Coexisting PCSK9 p.E32K and RNF213 p.R4810K Variants. Neurology. Genetics. 2023. 9. 5. e200099
Kotaro Noda, Yorito Hattori, Mika Hori, Yuriko Nakaoku, Akito Tanaka, Takeshi Yoshimoto, Kunihiro Nishimura, Takanori Yokota, Mariko Harada-Shiba, Masafumi Ihara. Amplified Risk of Intracranial Artery Stenosis/Occlusion Associated With RNF213 p.R4810K in Familial Hypercholesterolemia. JACC. Asia. 2023. 3. 4. 625-633