Rchr
J-GLOBAL ID：201601021422573322   Update date: Oct. 31, 2024

Sato Akira

サトウ アキラ | Sato Akira
Affiliation and department：
Tokyo University of Science Faculty of Pharmaceutical Sciences, Department of Pharmacy

About Tokyo University of Science Faculty of Pharmaceutical Sciences, Department of Pharmacy


Job title： Associate Professor
Homepage URL  (1)： https://pharmbiochemistrytus.com
Research field  (3)： Clinical pharmacy ,  Physiology ,  Pharmaceuticals - health and biochemistry
Research keywords  (6)： Biochemistry・Molecular Biology ,  Oligonucleotide therapeutics ,  Cancer ,  Apoptosis ,  Necrosis ,  Cell death
Research theme for competitive and other funds  (8)：
  • 2020 - 2023 Elucidation of selective cytotoxicity against malignant cells by chromone derivatives
  • 2017 - 2020 Novel anticancer strategy targeting microRNAs that regulate two types of cell death, necrosis and apoptosis
  • 2016 - 2019 Creation of novei anticancer lead compounds targeting the allosteric site of c-Met kinase
  • 2014 - 2017 Research on anticancer drug target that regulate two types of cell death, necrosis and apoptosis
  • 2012 - 2014 Analysis of switching mechanisms in two-types cell-death, necrosis and apoptosis
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Papers (77)：
  • Akira Kagawa, Akira Sato, Kimiko Makino, Issei Takeuchi. Therapeutic Effects of 30 nm Cyclosporin A-Loaded Nanoparticles Using PLGA-PEG-PLGA Triblock Copolymer for Transdermal Delivery in Mouse Models of Psoriasis. Applied Sciences. 2024. 14. 9. 3791
  • Chinatsu Kurasaka, Nana Nishizawa, Yoko Ogino, Akira Sato. Anticancer sensitivity and biological aspect of 5-fluorouracil-resistant human colorectal cancer HCT116 cells in three-dimensional culture under high- and low-glucose conditions. Nucleosides, Nucleotides & Nucleic Acids. 2024. 1-11
  • Nagwa S.M. Aly, Hiroaki Matsumori, Thi Quyen Dinh, Akira Sato, Shin-Ich Miyoshi, Kyung-Soo Chang, Hak Sun Yu, Takaaki Kubota, Yuji Kurosaki, Duc Tuan Cao, Gehan A. Rashed, Hye-Sook Kim. Evaluating the activity of N-89 as an oral antimalarial drug. Parasites, Hosts and Diseases. 2023. 61. 3. 282-291
  • Akira Sato, Akira Shimotsuma, Tetsuya Miyoshi, Yui Takahashi, Naoki Funayama, Yoko Ogino, Akiko Hiramoto, Yusuke Wataya, Hye-Sook Kim. Extracellular Leakage Protein Patterns in Two Types of Cancer Cell Death: Necrosis and Apoptosis. ACS Omega. 2023. 8. 28. 25059-25065
  • Ryo Okamoto, Koki Toya, Yoko Ogino, Akira Sato. Downregulation of long noncoding RNA <i>TP73-AS1</i> expression confers resistance to temozolomide in human glioblastoma cells. Nucleosides, Nucleotides & Nucleic Acids. 2023. 1-13
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MISC (35)：
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Books (6)：
  • 私の研究室「細胞の”死”を理解して, 抗がん剤の開発に繋げる」
    理大 科学フォーラム 2019
  • Short Communication “Nicotinamide adenine dinucleotide (NAD+) and cell aging” in New Research on Cell Aging and Death
    Nova Science Publishers, Inc., Hauppauge, NY 2018 ISBN:9781536136272
  • ゲノム創薬科学(田沼 靖一 編) 第2章 創薬標的分子の探索
    裳華房 2017 ISBN:9784785352363
  • PARP and Carcinogenesis, Cancer Drug Discovery and Development "PARP Inhibitors for Cancer Therapy"
    Springer International Publishing Switzerland 2015 2015 ISBN:9783319141503
  • 最新医学「感染症医薬品開発の現状」
    最新医学社 2012
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Lectures and oral presentations  (169)：
  • ヒト大腸がん細胞における5-Fluorouracil 代謝活性化経路の調節による5-FU耐性化の解明
    (日本薬学会第144年会(横浜) 2024)
  • 細胞死をネクローシスからアポトーシスに切替える長鎖非コードRNAの機能解析
    (第96回日本生化学会大会 2023)
  • 5-FU耐性機構としてのチミジル酸シンターゼによる5-FU活性代謝体FdUMPの捕捉と分解システムの解明
    (東京理科大学研究推進機構総合研究院(RIST)データサイエンス医療研究部門・デジタルトランスフォーメーション研究部門合同シンポジウム 2023)
  • 5-FU耐性機構としてのチミジル酸合成酵素による5-FU活性代謝体FdUMPの捕捉と分解システムの解明
    (第82回日本癌学会学術総会 2023)
  • 神経膠芽腫細胞のTMZ耐性機構における長鎖非コードRNAの関与
    (第67回日本薬学会 関東支部大会 2023)
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Education (4)：
  • 2005 - 2008 Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
  • - 2008 Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • 2003 - 2005 Okayama University The Graduate School of Natural Science and Technology
  • - 2003 Tohoku Pharmaceutical University Faculty of Pharmaceutical Science
Professional career (1)：
  • 博士(薬学) (岡山大学)
Work history (7)：
  • 2022/04 - 現在 Tokyo University of Science Faculty of Pharmaceutical Sciences Department of Pharmacy Associate Profesor
  • 2018/04 - 2022/03 Tokyo University of Science Faculty of Pharmaceutical Sciences
  • 2017/04 - 2018/03 Tokyo University of Science Faculty of Pharmaceutical Sciences
  • 2014/04 - 2017/03 Tokyo University of Science Faculty of Pharmaceutical Sciences Assistant Professor
  • 2013/09 - 2014/03 National Cancer Center Research Institute Division of Genome Stability Research Scientist
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Awards (3)：
  • 2017/06 - 第21回日本がん分子標的治療学会学術集会 第21回日本がん分子標的治療学会学術集会ポスター賞
  • 2016/09/17 - 平成28年度日本薬学会関東支部奨励賞
  • 2012/07 - 一般社団法人日本Cell Death学会 平成24年度日本Cell Death学会奨励優秀演題賞 優秀演題
Association Membership(s) (7)：
日本ポリフェノール学会 ,  日本Cell death学会 ,  THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE CANCER ASSOCIATION ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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