Lee-Okada Hyeon-Cheol

リケンテツ | Lee-Okada Hyeon-Cheol

Research field (4)： Medical biochemistry , Cell biology , Molecular biology , Pharmaceuticals - health and biochemistry

Research theme for competitive and other funds (12)：

2023 - 2026 Integrated multiomics analysis to investigate the mechanism of immunotherapy-resistant MAFLD-related hepatocarcinogenesis
2022 - 2025 極長鎖脂肪酸をターゲットとした新規抗癌治療戦略
2021 - 2024 Mechanism elucidation for influences of the Parkinson disease after appendectomy
2021 - 2024 ドコサヘキサエン酸選択的細胞内輸送経路の生理的意義の解明
2019 - 2024 Selective autophagy-mediated cellular regulations

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Papers (72)：

Hyeon-Cheol Lee-Okada, Chengxuan Xue, Takehiko Yokomizo. Recent advances on the physiological and pathophysiological roles of polyunsaturated fatty acids and their biosynthetic pathway. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2024. 1870. 1. 159564-159564
李賢哲, 横溝岳彦. 【脂質多様性の生物学と疾患制御】脂質多様性を生む脂肪酸不飽和化酵素. 医学のあゆみ. 2024. 289. 11. 815-819
安藤美沙, 李賢哲, 横溝岳彦. FADS1/2二重欠損マウスにおける脂肪肝の分子機構の解明. 脂質生化学研究. 2024. 66. 127-128
薛城軒, 李賢哲, 安藤美沙, 横溝岳彦. FADS1/2遺伝子のNAFLDリスクアレルを模倣する動物モデルの解析. 脂質生化学研究. 2024. 66. 129-130
李賢哲, 安藤美沙, 陳経権, 横溝岳彦. 肝臓特異的FADS1/2二重欠損マウスの作製と表現型解析. 脂質生化学研究. 2024. 66. 131-132

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MISC (18)：

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Lectures and oral presentations (43)：

Generation and application of animal models for a comprehensive and systematic understanding of physiological functions of polyunsaturated fatty acids
(2022)
雄性生殖における脂肪酸輸送体 (FATP1)の役割の解明
(第95回日本生化学会大会)
HDSF inhibits the activity of LYPLA1 and LYPLA2
(JCBL2022 2022)
The regulatory mechanism of Hormone-sensitive lipase (HSL) in 10T1/2 cell
(JCBL2022 2022)
The anti-HCV drug sofosbuvir inhibits Hormone-sensitive lipase
(JCBL2022 2022)

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Work history (1)：

2023/02 - 現在 Juntendo University Department of Biochemistry (I) Graduate School of Medicine Associate Professor

Association Membership(s) (4)：

THE JAPANESE BIOCHEMICAL SOCIETY , THE JAPANESE CONFERENCE ON THE BIOCHEMISTRY OF LIPIDS , 日本ケミカルバイオロジー学会 , 日本薬学会

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