2018 - 2022 Exploring the pathogenic mechanism of autism through the synaptic binding control by testosterone
2018 - 2021 Elucidation of pathogenic mechanism of sociality impaired dementia
Papers (4)：
Nan Yagishita-Kyo, Yuki Ikai, Tomoko Uekita, Akio Shinohara, Chihiro Koshimoto, Keisuke Yoshikawa, Kei Maruyama, Sosuke Yagishita. Testosterone interrupts binding of Neurexin and Neuroligin that are expressed in a highly socialized rodent, Octodon degus. Biochemical and biophysical research communications. 2021. 551. 54-62
,Encyclopedia of Signaling Molecules- contribution: CREB
2012
Encyclopedia of Signaling Molecules- contribution: CREB
2012
Lectures and oral presentations (8)：
Highly concentrative testosterone impaired social behavior by interrupting Neurexin and Neuroligin binding
(NEURO2022 The 45th Annual Meeting of the Japan Neuroscience Society 2022)
Molecular interactions of testosterone, Neurexin and Neuroligin, all of them are crucial for the onset of Autism Spectrum Disorder
(The 44th Annual Meeting of the Japan Neuroscience Society/The 1st CJK International Meeting 2021)
<I>O.degus</I>; a highly social rodent model for understanding pathogenic mechanisms of ASD.
(The 42nd Annual Meeting of the Molecular Biology Society of Japan 2019)
Molecular biological analysis of non-genetically modified Alzheimer’s disease model; <I>Octodon degus</I>.
(The 92nd Annual Meeting of the Japanese Biochemical Society 2019)
The effect of sex hormones on the interaction between synaptic adhesion proteins concerned with sociality.
(The 92nd Annual Meeting of the Japanese Pharmacological Society 2019)
