Yuhei Goto

Affiliation and department：

Research field (2)： Cell biology , Cell biology

Research keywords (10)： Quantitative Biology , 蛍光バイオセンサー , Optogenetics , Cell cycle , 細胞休眠 , 細胞質物性 , Fission yeast , Phytochrome , FCS/FCCS , CRISPR/Cas9 Knock-in

Research theme for competitive and other funds (7)：

2022 - 2025 Developing a platform for material production using optegenetic multistep switching
2022 - 2024 固体化した細胞質をもつ休眠細胞からの復帰機構の解明
2021 - 2022 タンパク質機能制御技術を用いた細胞生物学の創出
2019 - 2022 Cdk-サイクリンによるG1/Sチェックポイントの閾値決定機構の解明
2020 - 2021 相分離を利用したシグナル伝達人工制御系による ERK/Akt細胞増殖機構の解明

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Papers (19)：

Keiichiro Sakai, Yohei Kondo, Yuhei Goto, Kazuhiro Aoki. Cytoplasmic fluidization contributes breaking spore dormancy in fission yeast. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024
Keiichiro Sakai, Kazuhiro Aoki, Yuhei Goto. Live-cell fluorescence imaging and optogenetic control of PKA kinase activity in fission yeastSchizosaccharomyces pombe. Yeast. 2024
Hironori Sugiyama, Yuhei Goto, Yohei Kondo, Damien Coudreuse, Kazuhiro Aoki. Live-cell imaging defines a threshold in CDK activity at the G2/M transition. Developmental Cell. 2024
Yoko Otsubo, Akira Yamashita, Yuhei Goto, Keiichiro Sakai, Tetsushi Iida, Shinji Yoshimura, Katsuki Johzuka. Cellular responses to compound stress induced by atmospheric-pressure plasma in fission yeast. Journal of Cell Science. 2023
Akinobu Nakamura, Yuhei Goto, Hironori Sugiyama, Shinya Tsukiji, Kazuhiro Aoki. Chemogenetic Manipulation of Endogenous Proteins in Fission Yeast Using a Self-Localizing Ligand-Induced Protein Translocation System. ACS chemical biology. 2023

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MISC (7)：

後藤祐平, 青木一洋. GPCRリガンドセンサーの開発. 月刊「細胞」2023年 4月臨時増刊号蛍光タンパク質センサー. 2023
Akinobu Nakamura, Yuhei Goto, Yohei Kondo, Kazuhiro Aoki. Shedding light on developmental ERK signaling with genetically encoded biosensors. Development. 2021. 148. 18
後藤祐平, 青木一洋. ライブセルイメージングによる細胞内シグナル伝達の可視化と光操作. 顕微鏡. 2021. 56. 2. 54-58
Yuhei Goto, Yohei Kondo, Kazuhiro Aoki. Visualization and Manipulation of Intracellular Signaling. Advances in experimental medicine and biology. 2021. 1293. 225-234
GOTO Yuhei, AOKI Kazuhiro. Red/far-red Light-induced Control of Intracellular Signaling in Mammalian Cells. Seibutsu Butsuri. 2019. 59. 6. 327-329

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Lectures and oral presentations (4)：

CDK活性のライブセルイメージングから酵母の細胞周期を考える
(第24回酵母合同シンポジウム 2023)
Development of biosensors for measuring TOR and PKA activity to elucidate the nutrition sensing system in fission yeast
(The 61st Annual Meeting of the Biophysical Society of Japan 2023)
Development of optogenetic tools to manipulate cell cycle checkpoints
(3rd Optogenetic Technologies and Applications Conference 2022)
Live-Cell Imaging and Optogenetics Reveals AND Gate Role of ERK and Akt in G1/S transition
(2019)

Education (3)：

2011 - 2017 Tokyo University
2009 - 2011 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
2007 - 2009 The University of Tokyo College of Arts and Sciences

Professional career (1)：

博士(理学) (東京大学)

Work history (4)：

2024/06 - 現在京都大学生命科学研究科准教授
2019/11 - 2024/05 National Institute for Basic Biology Division of Quantitative Biology Research Associate
2017/04 - 2019/10 National Institute for Basic Biology Division of quantitative biology Post-Doc
2015/04 - 2017/03 Japan Society for the Promotion of Science

Committee career (4)：

2021/02 - 現在酵母遺伝資源運営委員
2018/10 - 2023/03 酵母研究若手の会運営副委員長
2017/08 - 2023/03 酵母研究若手の会運営委員
2022/09 - 2022/09 酵母遺伝学フォーラム第55回研究報告会実行委員

Awards (4)：

2024/02 - National Institute for Basic Biology NIBB Young Scientist Award
2020/06 - 日本細胞生物学会若手優秀発表賞
2019/11 - 酵母細胞研究会地神芳文記念研究助成賞オプトジェネティクスを用いた分裂酵母の細胞周期操作
2013/03 - 東京大学大学院理学系研究科理学系研究科研究奨励賞(修士)

Association Membership(s) (4)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , 酵母遺伝学フォーラム , JAPAN SOCIETY FOR CELL BIOLOGY , 日本農芸化学会

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