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Rchr

J-GLOBAL ID：201701008994743807 Update date: Feb. 04, 2025

Eiji Kawamoto

カワモトエイジ | Eiji Kawamoto

Affiliation and department：
Other affiliations (1)：

Mie University

Homepage URL (1)： http://kyoin.mie-u.ac.jp/profile/2775.html

Research field (5)： Food sciences , Human interfaces and interactions , Biomaterials , Biomedical engineering , General surgery, pediatric surgery

Research keywords (12)：経腸栄養 , Gene editting , Trauma , Acute Lung Injury , Drug Delivery System , Immune Suppression , Thrombomodulin , hybrid simulation training , Communication network , Integrin , Extracellular Vesicle , Sepsis

Research theme for competitive and other funds (24)：

2024 - 2028 Development of a novel treatment and prognostic model for post-cardiac arrest syndrome using the M2 Macrophage Designer Exosome
2023 - 2027 Methemoglobinemia releases macrophage exosomes and causes ICU delirium
2022 - 2025 Targeting integrin signaling for the treatment of COVID-19
2022 - 2025 T細胞移入腸炎モデルを用いた骨格筋由来アイリシンの粘膜治癒効果と作用機序の解明
2022 - 2025 Identifying PD-L1-mediated immune dysregulation in post-cardiac arrest syndrome.

2022 - 2025 肺炎・腎不全-関連ICUせん妄の予測AIモデルの開発とフィジビリティ検証

2022 - 2025 Study of the roles played by exosomal microRNAs of intestinal epithelial cells in downregulating septic inflammations

2021 - 2024 Development of integrin-targeted therapy for novel coronavirus-induced ARDS

2021 - 2024 Practical application of diagnostic method for pesticide poisoning by skin volatile substance analysis

2021 - 2024 Development of measures to promote home based rehabilitation using virtual reality (VR)

2021 - 2024 Elucidation of the mechanism by which exosomal PD-L1 induces septic immune paralysis

2019 - 2024 Aberrant skeletal muscle-brain communication in sepsis-associated encephalopathy: Elucidating the pathogenic roles of skeletal muscle-derived exosomes

2019 - 2022 Effects of recombinant thrombomodulin on intestinal mucosal healing

2019 - 2022 Study of the anti-inflammatory roles of the exosomes from intestinal epithelial cells in sepsis via a paracrine effect

2018 - 2022 Behavioral Big Data Analysis Reveals a Pivotal Role of ICU Staff in Promoting Inter- and Intra-Staff Communication.

2018 - 2021 Exosomal regulation of leukocyte trafficking

2018 - 2021 Treatment of sepsis with exosomal thrombomodulin

2017 - 2021 ウェアラブルとICTを用いて、PICS(post intensive care syndrome, 集中治療後症候群)発症リスク患者を、在宅で持続的にモニターするシステムの構築

2017 - 2020 Study of objective and quantitative measures of anesthesia skills and assessment of learning effect using automatic analysis by artificial intelligence system

2016 - 2019 The role of gap junction-mediated regulation of endothelial cellular stiffness

2016 - 2018 The ability of human extracellular vesicles to augment inflammatory host response in septic shock

2016 - 2018 Interaction between beta2 integrin and thrombomodulin effect to immunothrombosis

2014 - 2016 Analysis of the interaction between neutrophil and thrombomodulin.

2012 - 2015 Introduction of Rapid Response System (RRS) in small sized and middle sized hospitals in Japan, and establishment of an RRS online registry

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Papers (88)：

Ryo Esumi, Hiroki Funao, Eiji Kawamoto, Ryota Sakamoto, Asami Ito-Masui, Fumito Okuno, Toru Shinkai, Atsuya Hane, Kaoru Ikejiri, Yuichi Akama, et al. Machine Learning-Based Prediction of Delirium and Risk Factor Identification in ICU Patients with Burns: A Retrospective Observational Study. JMIR formative research. 2025
Hiroki Funao, Ryo Momosaki, Mayumi Tsujikawa, Eiji Kawamoto, Ryo Esumi, Motomu Shimaoka. Virtual Reality-Applied Home-Visit Rehabilitation for Patients With Chronic Pain: Protocol for Single-Arm Pre-Post Comparison Study. JMIR Research Protocols. 2024. 13. e58734-e58734
Arong Gaowa, Supasuta Leangpanich, Eun Jeong Park, Eiji Kawamoto, Motomu Shimaoka. Irisin promotes intestinal epithelial cell proliferation via Wnt/β-catenin and focal adhesion kinase signaling pathways. Scientific reports. 2024. 14. 1. 25702-25702
Yuichi Akama, Eun Jeong Park, Naoko Satoh-Takayama, Atsushi Ito, Eiji Kawamoto, Arong Gaowa, Eri Matsuo, Satoshi Oikawa, Masafumi Saito, Shigeaki Inoue, et al. Roles of programmed death-1 and muscle innate lymphoid cell-derived interleukin 13 in sepsis-induced intensive care unit-acquired weakness. Journal of cachexia, sarcopenia and muscle. 2024. 15. 5. 1999-2012
Khwanchanok Mokmued, Gideon Obeng, Eiji Kawamoto, Siqingaowa Caidengbate, Supasuta Leangpanich, Yuichi Akama, Arong Gaowa, Motomu Shimaoka, Eun Jeong Park. miR-200c-3p regulates α4 integrin-mediated T cell adhesion and migration. Experimental cell research. 2024. 440. 2. 114146-114146

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MISC (225)：

川本英嗣. 【QQ CASES COLLECTION 100】仮想現実がICU患者の痛みを取り除く. 救急医学. 2024. 48. 6. 710-711
船尾浩貴, 辻川真弓, 川本英嗣, 百崎良. バーチャルリアリティ(VR)を利用した訪問リハビリテーションによる疼痛緩和効果慢性疼痛患者を対象とした前後比較試験. リハビリテーション栄養. 2024. 8. 1. 165-166
植木彩加, 刑部全晃, 中西丈比佐, 近藤誠, 中井康雄, 波部幸司, 山中恵一, 刀根慎恵, 川本英嗣. Aeromonas hydrophiliaによる壊死性筋膜炎の1例. 日本皮膚科学会雑誌. 2024. 134. 4. 789-789
山口貴則, 加藤隆史, 笠井岳志, 大岩加奈, 安達佳奈, 中林明璃, 守屋夏樹, 藤永真奈美, 木下玄太, 羽根敦也, et al. 相互参加型ハンズオンによる腹臥位療法コモンズ創出への取り組み. 日本呼吸療法医学会学術集会プログラム・抄録集. 2024. 46th (Web)
石倉健, 中林明璃, 木下玄太, 藤永真奈美, 守屋夏樹, 羽根敦也, 奥野郁斗, 田中康次郎, 池尻薫, 山口貴則, et al. ドクターヘリ運用における12誘導心電図伝送の有用性について. 日本航空医療学会雑誌. 2024. 25. 2. 80-80

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Books (4)：

SimWars : 救急シミュレーションシナリオ集
メディカル・サイエンス・インターナショナル 2017 ISBN:9784895928892
FCCSプロバイダーマニュアル
FCCS運営委員会, JSEPTIC(日本集中治療教育研究会), メディカル・サイエンス・インターナショナル (発売) 2013 ISBN:9784895927499
RRS院内救急対応システム : 医療安全を変える新たなチーム医療
メディカル・サイエンス・インターナショナル 2012 ISBN:9784895927178
Difficult Airway Management : 気道管理スキルアップ講座
克誠堂出版 2010 ISBN:9784771903753

Lectures and oral presentations (2)：

Integrin and PD-1 Ligand Expression on Circulating Extracellular Vesicles in Systemic Inflammatory Response Syndrome and Sepsis
(41 st ANNUAL CONFERENCE ON SHOCK 2018)
細胞外小胞(EV)インテグリンの敗血症病態への関与の研究を目的としたCRISPR/Cas9遺伝子編集技術を用いたインテグリンノックアウトEVがそれぞれSIRSの作製
(第33回日本ショック学会総会)

Education (2)：

2013 - 2017 Mie University Molecular Pathobiology
1998 - 2004 Toyama University

Professional career (1)：

医学博士 (三重大学分子病態学)

Work history (12)：

2023/07 - 現在 Mie University Hospital Intensive Care Unit Associate professor
2022/05 - 現在 Mie University
2019/02 - 現在三重大学医学部付属病院救命救急センター
2017/04 - 現在 Mie University
2021/11 - 2022/06 Mie University Graduate School of Medicine

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Committee career (2)：

2019/07 - 現在日本Shock学会評議員
2013/01 - 2017/12 日本救急医学会学生・研修医部会運用特別委員会委員長

Awards (1)：

2017/09 - 日本shock学会会長賞敗血症患者の細胞外小胞にはインテグリン,PD-L1,PD-L2が発現する

Association Membership(s) (9)：

日本免疫学会 , THE JAPAN SOCIETY FOR CLINICAL ANESTHESIA , The Japan Shock Society , THE JAPANESE SOCIETY OF INTENSIVE CARE MEDICINE , JAPANESE SOCIETY OF ANESTHESIOLOGISTS , JAPANESE ASSOCIATION FOR ACUTE MEDICINE , 日本内科学会 , 日本血栓止血学会 , 日本航空医療学会

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