Rchr
J-GLOBAL ID:201701009584156404
Update date: May. 26, 2024
Kojima Ryosuke
コジマ リョウスケ | Kojima Ryosuke
Affiliation and department:
Job title:
Associate Professor
Homepage URL (2):
https://cbmi.m.u-tokyo.ac.jp/members
,
https://scholar.google.com/citations?user=lP4Uu2MAAAAJ&hl=ja
Research field (6):
Chemical biology
, Biomaterials
, Biomedical engineering
, Biochemistry
, Pharmaceuticals - chemistry and drug development
, Pharmaceuticals - analytical and physicochemistry
Research keywords (10):
Synthetic Biology
, Chemical Biology
, Cell engineering
, Protein engineering
, Extracellular vesicles
, Cell-cell communication
, Bioluminogenic probe
, Fluorescence probe
, Drug Delivery System
, Cancer
Research theme for competitive and other funds (15):
- 2022 - 2028 Research on intracellular degradation focusing on membranous structures
- 2023 - 2028 DNAイベントレコーダー細胞
- 2024 - 2027 細胞間コミュニケーションの網羅的記録を基軸とした「適応多様性」の理解
- 2024 - 2027 細胞表面抗原に応答するレポーター酵素スイッチの創製とがん診断・治療への応用
- 2023 - 2027 Selective wound healing senolytics targeting senescent cells in wound exudate
- 2022 - 2025 合成生物学的手法による細胞外小胞の包括的理解と発展的利用
- 2019 - 2024 多次元・ネットワーク化計測による細胞外微粒子の多様性と動態の解明
- 2020 - 2023 Development of functional Raman probes for innovative multiplex imaging
- 2020 - 2023 Innovative multiplex imaging with functional Raman probes
- 2020 - 2023 機能性小分子・タンパク質ペアを利用したがん蛍光イメージングの新手法
- 2020 - 2023 Exploiting exosome biology to design polyvalent targeting strategies for in situ cell programming
- 2017 - 2021 In vivo における多対多のアッセイを基盤としたエクソソームターゲティングシステムの効率的探索
- 2018 - 2019 がん表面の任意の抗原を認識して迅速にシグナルを発する蛍光プローブの開発
- 2014 - 2017 Synthetis of functional cells capable of rapid modulation of biological systems for future therapies
- Development of novel luciferin probes that function in specific cells in vivo
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Papers (48):
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Hiroyoshi Fujioka, Yuta Murao, Momoko Okinaka, Spencer John Spratt, Jingwen Shou, Minoru Kawatani, Ryosuke Kojima, Ryo Tachibana, Yasuteru Urano, Yasuyuki Ozeki, et al. Cyano-Hydrol green derivatives: Expanding the 9-cyanopyronin-based resonance Raman vibrational palette. Bioorganic & Medicinal Chemistry Letters. 2024. 106. 129757-129757
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Yugo Kuriki, Mari Sogawa, Toru Komatsu, Minoru Kawatani, Hiroyoshi Fujioka, Kyohhei Fujita, Tasuku Ueno, Kenjiro Hanaoka, Ryosuke Kojima, Rumi Hino, et al. Modular Design Platform for Activatable Fluorescence Probes Targeting Carboxypeptidases Based on ProTide Chemistry. Journal of the American Chemical Society. 2023
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Koki Kunitake, Tadahaya Mizuno, Kazuki Hattori, Chitose Oneyama, Mako Kamiya, Sadao Ota, Yasuteru Urano, Ryosuke Kojima. Barcoding of small extracellular vesicles with CRISPR-gRNA enables comprehensive, subpopulation-specific analysis of their biogenesis/release regulators. bioRxiv. 2023
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Jingwen Shou, Ayumi Komazawa, Yuusaku Wachi, Minoru Kawatani, Hiroyoshi Fujioka, Spencer John Spratt, Takaha Mizuguchi, Kenichi Oguchi, Hikaru Akaboshi, Fumiaki Obata, et al. Super-resolution vibrational imaging based on photoswitchable Raman probe. Science advances. 2023. 9. 24. eade9118
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Takafumi Kasai, Kyohhei Fujita, Toru Komatsu, Tasuku Ueno, Ryosuke Kojima, Kenjiro Hanaoka, Yasuteru Urano. Development of near-infrared fluorescence probe for the selective detection of severe hypoxia. ChemRxiv. 2023
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MISC (14):
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小嶋良輔, 國武 厚貴. 合成生物学的アプローチが可能とする細胞外小胞の理解と発展的利用. 生化学. 2023. 95. 2. 194-200
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小嶋良輔. “Designer EV”の開発の現状と将来展望. 実験医学増刊. 2021. 39. 20
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Ryosuke Kojima (Editor). Methods in Molecular Biology, Mammalian Cell Engineering. 2021
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小嶋良輔. 遺伝子工学的アプローチを利用した エクソソームのエンジニアリングとその応用. 膜. 2020. 2. 62-67
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小嶋 良輔. Top Researchers インタビュー. 2019
more...
Patents (2):
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Library of barcoded extracellular vesicles
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New NIR-emitting luciferins
Education (3):
- - 2014 The University of Tokyo Graduate School of Pharmaceutical Sciences
- - 2009 The University of Tokyo Department of Pharmaceutical Sciences
- - 2005 Komaba-toho High School
Professional career (1):
- PhD (The University of Tokyo)
Work history (10):
- 2022/11 - 現在 Nagoya University, Institute of Nano-Life-Systems, Institutes of Innovation for Future Society Institute of Innovation for Future Society Nano-Life System Visiting Associate Professor
- 2022/10 - 現在 The University of Tokyo Graduate School of Medicine Associate Professor
- 2022/04 - 現在 JST FOREST researcher
- 2020/04 - 2022/10 Nagoya University Institute of Innovation for Future Society Nano-Life System Visiting Assistant Professor
- 2017/07 - 2022/09 The University of Tokyo Graduate School of Medicine Assistant Professor
- 2017/10 - 2021/03 JST PRESTO Researcher
- 2014/07 - 2017/06 Human Frontier Science Program (HFSP) Long-term Fellow
- 2014/07 - 2017/06 ETH Zurich Department of Biosystems Science and Engineering (D-BSSE), Fussenegger lab Postdoc
- 2014/04 - 2014/06 PATH (Global Health Organization) Internship (Funded by Global Leadership Program, The University of Tokyo)
- 2011/04 - 2014/03 JSPS research fellow (DC1)
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Awards (11):
- 2024/05 - International Society of Extracellular Vesicles Journal of Extracellular Biology Oral Award, ISEV2024
- 2023/04 - MEXT Young Scientist Prize
- 2022/04 - CREST Fine Particles, Young Innovator Award
- 2019/03 - Human Frontier Science Program (HFSP) Career Development Award
- 2018/09 - 12th Bio-Related Chemistry Symposium Best Lectureship Award
- 2018/06 - 13th Meeting of Japanese Society for Chemical Biology Royal Society of Chemistry Poster Award
- 2018/06 - 13th Annual Meeting of the Japanese Society for Molecular Imaging Best Presentation Award
- 2014/10 - Swiss-Japanese Chemical Biology Symposium 2014 Best Poster Award
- 2013/06 - 8th Annual Meeting of the Japanese Society for Molecular Imaging Best Presentation Award
- 2011/09 - 2011 World Molecular Imaging Congress Student Travel Stipend Award
- 2011/06 - The 11th Life Science Network Symposium, The University of Tokyo Poster Award
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Association Membership(s) (4):
Japanese Society of Chemical Biology
, The Pharmaceutical Society of Japan
, The Japanese Biochemical Society
, Japanese Society for Molecular Imaging
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