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J-GLOBAL ID：201701009584156404   Update date: Mar. 21, 2025

Kojima Ryosuke

コジマ リョウスケ | Kojima Ryosuke
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Affiliation and department：
The University of Tokyo Graduate School of Medicine

About The University of Tokyo Graduate School of Medicine


Job title： Associate Professor
Homepage URL  (2)： https://cbmi.m.u-tokyo.ac.jp/members ,  https://scholar.google.com/citations?user=lP4Uu2MAAAAJ&hl=ja
Research field  (6)： Chemical biology ,  Biomaterials ,  Biomedical engineering ,  Biochemistry ,  Pharmaceuticals - chemistry and drug development ,  Pharmaceuticals - analytical and physicochemistry
Research keywords  (10)： Synthetic Biology ,  Chemical Biology ,  Cell engineering ,  Protein engineering ,  Extracellular vesicles ,  Cell-cell communication ,  Bioluminogenic probe ,  Fluorescence probe ,  Drug Delivery System ,  Cancer
Research theme for competitive and other funds  (15)：
  • 2022 - 2028 Research on intracellular degradation focusing on membranous structures
  • 2023 - 2028 DNAイベントレコーダー細胞
  • 2024 - 2027 細胞間コミュニケーションの網羅的記録を基軸とした「適応多様性」の理解
  • 2024 - 2027 細胞表面抗原に応答するレポーター酵素スイッチの創製とがん診断・治療への応用
  • 2023 - 2027 Selective wound healing senolytics targeting senescent cells in wound exudate
Show all
Papers (50)：
  • Ziyi Wang, Ryosuke Kojima, Rikuki Kiji, Kyohhei Fujita, Ryo Tachibana, Taku Uchiyama, Yoshihiro Minagawa, Tadahaya Mizuno, Kiyohiko Igarashi, Hiroyuki Noji, et al. Low-Background Cancer Imaging With a Bioorthogonal Fluorescence Probe and Engineered Reporter Enzyme Bearing a Targeting Moiety. bioRxiv. 2025
  • Yuichiro Iwamoto, Benjamin Salmon, Yusuke Yoshioka, Ryosuke Kojima, Alexander Krull, Sadao Ota. High throughput analysis of rare nanoparticles with deep-enhanced sensitivity via unsupervised denoising. Nature Communications. 2025
  • Takafumi Kasai, Kyohhei Fujita, Toru Komatsu, Tasuku Ueno, Ryosuke Kojima, Kenjiro Hanaoka, Yasuteru Urano. Development of a near-infrared fluorescent probe for the selective detection of severe hypoxia. RSC Chemical Biology. 2025
  • Mamiko Nakadate, Ryosuke Kojima, Naoki Seike, Ryo Tachibana, Kyohhei Fujita, Mako Kamiya, Andreas Plückthun, Yasuteru Urano. New class of fluorogenic probes for antigens based on DARPin-silicon pyronine conjugates. ChemRxiv. 2024
  • Koki Kunitake, Tadahaya Mizuno, Kazuki Hattori, Chitose Oneyama, Mako Kamiya, Sadao Ota, Yasuteru Urano, Ryosuke Kojima. Barcoding of small extracellular vesicles with CRISPR-gRNA enables comprehensive, subpopulation-specific analysis of their biogenesis and release regulators. Nature communications. 2024. 15. 1. 9777-9777
ｍore...
MISC (14)：
  • 小嶋良輔, 國武 厚貴. 合成生物学的アプローチが可能とする細胞外小胞の理解と発展的利用. 生化学. 2023. 95. 2. 194-200
  • 小嶋良輔. “Designer EV”の開発の現状と将来展望. 実験医学増刊. 2021. 39. 20
  • Ryosuke Kojima (Editor). Methods in Molecular Biology, Mammalian Cell Engineering. 2021
  • 小嶋良輔. 遺伝子工学的アプローチを利用した エクソソームのエンジニアリングとその応用. 膜. 2020. 2. 62-67
  • 小嶋 良輔. Top Researchers インタビュー. 2019
ｍore...
Patents (2)：
  • Library of barcoded extracellular vesicles
  • New NIR-emitting luciferins
Education (3)：
  • - 2014 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • - 2009 The University of Tokyo Department of Pharmaceutical Sciences
  • - 2005 Komaba-toho High School
Professional career (1)：
  • PhD (The University of Tokyo)
Work history (10)：
  • 2022/11 - 現在 Nagoya University, Institute of Nano-Life-Systems, Institutes of Innovation for Future Society Institute of Innovation for Future Society Nano-Life System Visiting Associate Professor
  • 2022/10 - 現在 The University of Tokyo Graduate School of Medicine Associate Professor
  • 2022/04 - 現在 JST FOREST researcher
  • 2020/04 - 2022/10 Nagoya University Institute of Innovation for Future Society Nano-Life System Visiting Assistant Professor
  • 2017/07 - 2022/09 The University of Tokyo Graduate School of Medicine Assistant Professor
Show all
Awards (11)：
  • 2024/05 - International Society of Extracellular Vesicles Journal of Extracellular Biology Oral Award, ISEV2024
  • 2023/04 - MEXT Young Scientist Prize
  • 2022/04 - CREST Fine Particles, Young Innovator Award
  • 2019/03 - Human Frontier Science Program (HFSP) Career Development Award
  • 2018/09 - 12th Bio-Related Chemistry Symposium Best Lectureship Award
Show all
Association Membership(s) (4)：
Japanese Society of Chemical Biology ,  The Pharmaceutical Society of Japan ,  The Japanese Biochemical Society ,  Japanese Society for Molecular Imaging
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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