Okada Takaharu

Affiliation and department：
Job title： Team Leader

Research field (2)： Cell biology , Immunology

Research keywords (4)： Peripheral Nervous System , Bioimaging , Adaptive Immunity , Inflammation

Research theme for competitive and other funds (8)：

2020 - 2025 ウイルス-人体相互作用ネットワークの理解と制御
2019 - 2022 Elucidation of neuroepigenetic mechanism underlying itch hypersensitivity in atopic dermatitis
2015 - 2017 Molecular mechanisms of the itch sensation and skin inflammation induced by epidermal tight junction barrier deficiency
2010 - 2016 Multi-dimensional fluorescent live imaging of cellular functions and molecular activities
2010 - 2015 Two-photon imaging of cellular function in tumor immunity and immune dysregulation

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Papers (56)：

Keitaro Fukuda, Yoshihiro Ito, Yuki Furuichi, Takeshi Matsui, Hiroto Horikawa, Takuya Miyano, Takaharu Okada, Mark van Logtestijn, Reiko J. Tanaka, Atsushi Miyawaki, et al. Three stepwise pH progressions in stratum corneum for homeostatic maintenance of the skin. Nature Communications. 2024. 15. 1
Sonoko Takahashi, Sotaro Ochiai, Jianshi Jin, Noriko Takahashi, Susumu Toshima, Harumichi Ishigame, Kenji Kabashima, Masato Kubo, Manabu Nakayama, Katsuyuki Shiroguchi, et al. Sensory neuronal STAT3 is critical for IL-31 receptor expression and inflammatory itch. Cell Reports. 2023. 42. 12. 113433-113433
Kenji Usui, Chisa Nakashima, Sonoko Takahashi, Takaharu Okada, Yoshihiro Ishida, Saeko Nakajima, Akihiko Kitoh, Takashi Nomura, Teruki Dainichi, Tetsuya Honda, et al. TRPV1-positive sensory nerves and neuropeptides are involved in epidermal barrier repair after tape-stripping in mice. Journal of Allergy and Clinical Immunology. 2023
Chen-Hao Yeh, Joel Finney, Takaharu Okada, Tomohiro Kurosaki, Garnett Kelsoe. Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells. Immunity. 2022. 55. 2. 272-289.e7
Takeshi Matsui, Nanako Kadono-Maekubo, Yoshiro Suzuki, Yuki Furuichi, Keiichiro Shiraga, Hiroyuki Sasaki, Azusa Ishida, Sonoko Takahashi, Takaharu Okada, Kiminori Toyooka, et al. A unique mode of keratinocyte death requires intracellular acidification. Proceedings of the National Academy of Sciences. 2021. 118. 17. e2020722118-e2020722118

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MISC (8)：

石亀晴道, 石亀晴道, HERNDLER-BRANDS Dietmer, 新中須亮, 井上毅, 米谷耕平, 黒崎知博, 黒崎知博, FLAVELL Richard, 岡田峰陽. エフェクターCD8陽性T細胞の分化の可塑性によりメモリーCD8陽性T細胞の多様性が形成される. 日本インターフェロン・サイトカイン学会学術集会抄録集. 2018. 83rd
河本新平, 服部正平, FAGARASAN Sidonia, 丸谷美香子, 加藤ルシア, 須田亙, 新幸二, 土井靖子, 筒井裕美, 本田賢也, et al. W2-2 Foxp3+ T細胞,IgA及び腸内細菌叢の間に見られる相互制御ループの解明. 日本臨床免疫学会会誌. 2014. 37. 4. 306a-306a
Dirk Baumjohann, Takaharu Okada, K. Ansel. Establishing the kinetics of TFH cell development in vivo. JOURNAL OF IMMUNOLOGY. 2011. 186
Irina L. Grigorova, Susan R. Schwab, Tri Giang Phan, Trung H. M. Pham, Takaharu Okada, Jason G. Cyster. Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells (vol 10, pg 58, 2009). NATURE IMMUNOLOGY. 2009. 10. 2. 223-223
Christopher D. C. Allen, Takaharu Okada, Jason G. Cyster. Chemokines and germinal center organization in vivo. JOURNAL OF IMMUNOLOGY. 2006. 176. S28-S28

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Professional career (2)：

Ph.D.
修士(工学) (京都大学)

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