Watanabe Tsubasa

ワタナベツバサ | Watanabe Tsubasa

Affiliation and department：

Research field (1)： Radiology

Research keywords (4)：放射線生物学 , 放射線腫瘍学 , Immune responses after irradiation , Neutron Capture Therapy

Research theme for competitive and other funds (11)：

2023 - 2026 Technology platform for clinical application of multi-targeted neutron capture therapy for brain tumors
2023 - 2026 免疫細胞のホウ素薬剤取込能を評価しホウ素中性子捕捉療法後の免疫への影響を解明する
2021 - 2023 ホウ素中性子捕捉療法の難治性非腫瘍性疾患への適応拡大のための基盤技術開発
2020 - 2023 ホウ素中性子捕捉療法により誘発される宿主免疫反応への影響解析
2021 - 2022 中性子捕捉ナイフシステムを用いた非腫瘍性難治性疾患の治療法確立

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Papers (55)：

Takeshi Sano, Ryoichi Saito, Rihito Aizawa, Tsubasa Watanabe, Kaoru Murakami, Yuki Kita, Kimihiko Masui, Takayuki Goto, Takashi Mizowaki, Takashi Kobayashi. Current trends in the promising immune checkpoint inhibition and radiotherapy combination for locally advanced and metastatic urothelial carcinoma. International Journal of Clinical Oncology. 2023. 28. 12. 1573-1584
Yoshihide Hattori, Tooru Andoh, Shinji Kawabata, Naonori Hu, Hiroyuki Michiue, Hiroyuki Nakamura, Takahiro Nomoto, Minoru Suzuki, Takushi Takata, Hiroki Tanaka, et al. Proposal of recommended experimental protocols for in vitro and in vivo evaluation methods of boron agents for neutron capture therapy. Journal of radiation research. 2023
Yoshiki Fujikawa, Yusuke Fukuo, Kai Nishimura, Kohei Tsujino, Hideki Kashiwagi, Ryo Hiramatsu, Naosuke Nonoguchi, Motomasa Furuse, Toshihiro Takami, Naonori Hu, et al. Evaluation of the Effectiveness of Boron Neutron Capture Therapy with Iodophenyl-Conjugated closo-Dodecaborate on a Rat Brain Tumor Model. Biology. 2023. 12. 9
Tsubasa Watanabe, Tomohiro Yoshikawa, Hiroki Tanaka, Yuko Kinashi, Genro Kashino, Shin-Ichiro Masunaga, Toshimitsu Hayashi, Koki Uehara, Koji Ono, Minoru Suzuki. Pharmacokinetic Study of 14C-Radiolabeled p-Boronophenylalanine (BPA) in Sorbitol Solution and the Treatment Outcome of BPA-Based Boron Neutron Capture Therapy on a Tumor-Bearing Mouse Model. European journal of drug metabolism and pharmacokinetics. 2023. 48. 4. 443-453
Hideki Kashiwagi, Yoshihide Hattori, Shinji Kawabata, Ryo Kayama, Kohei Yoshimura, Yusuke Fukuo, Takuya Kanemitsu, Hiroyuki Shiba, Ryo Hiramatsu, Toshihiro Takami, et al. Multi-Targeted Neutron Capture Therapy Combined with an 18 kDa Translocator Protein-Targeted Boron Compound Is an Effective Strategy in a Rat Brain Tumor Model. Cancers. 2023. 15. 4

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MISC (66)：

真田悠生, 高田卓志, 田中浩基, 櫻井良憲, 渡邉翼. Attempts to enhance the anti-tumor effects of BNCT by targeting the tumor microenvironment. KURNS-EKR (Web). 2023. 17
真田悠生, 渡邉翼. Recent biological studies for boron neutron capture therapy (BNCT). 放射線生物研究. 2023. 58. 2
新津明穂, 山本凌大, 真田悠生, 渡邉翼, 増永慎一郎, 増永慎一郎, 辻美恵子, 平山佑, 永澤秀子. Development of a novel boron carrier for BNCT exploiting a tumor-specific amino acid transport system. 日本薬学会年会要旨集(Web). 2023. 143rd
辻野晃平, 川端信司, 柏木秀基, 吉村亘平, 香山諒, 福尾祐介, 竹内孝治, 平松亮, 西村開, 川井一貴, et al. インテグリン標的を有したcRGD-MID-ACを使用するホウ素中性子捕捉療法の可能性. 日本分子脳神経外科学会プログラム・抄録集. 2022. 22nd
SASAKI Akinori, TAKATA Takushi, TAMARI Yuki, WATANABE Tsubasa, HU Naonori, HU Naonori, KAWABATA Shinji, KUDO Yoshihiro, MITSUMOTO Toshinori, MATSUBAYASHI Nishiki, et al. Study of Optimal Irradiation Method for Superficial Tumors Using a Hydrogel Bolus in Cyclotron-based BNCT. 日本放射線技術学会総会学術大会予稿集. 2021. 77th

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Books (1)：

ベッドサイド泌尿器科学(改定第5版)
南江堂

Lectures and oral presentations (26)：

ホウ素中性子捕捉療法の治療効果改善のための基礎放射線生物研究
(3. 第61回日本癌治療学会学術集会 2023)
シングルセルRNAseq解析による腫瘍細胞のLAT1発現と細胞周期との関連解明
(第19回日本中性子捕捉療法学会 2023)
LAT1 expression in tumor cells and LAT1 expression levels in different types of human tumors
(2023)
ホウ素中性子捕捉療法の課題と解決法の模索
(日本放射線影響学会第65回大会 2022)
モーニングセミナー: BNCTの生物学
(日本放射線腫瘍学会夏季セミナー 2022)

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Education (2)：

2013 - 2017 Kyoto University Graduate School of Medicine Graduate School of Medicine
2003 - 2009 Kyoto University Faculty of Medicine Department of Medical Science

Professional career (1)：

博士(医学) (京都大学)

Work history (7)：

2023/09 - 現在 Kyoto University
2020/10 - 2023/08 Kyoto University
2017/04 - 2020/09 Kyoto University Institute for Integrated Radiation and Nuclear Science Assistant Professor
2017/10 - 2019/09 Albert-Ludwigs-Universität Freiburg Department of Radiation Oncology Post-doctoral researcher
2014/04 - 2017/03 Japan Society for the Promotion of Science Research fellow (DC1)

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Committee career (7)：

2022/12 - 現在 Journal of Radiation Research Managing Editor
2022/12 - 現在日本放射線腫瘍学会学術委員会
2022/12 - 現在日本放射線腫瘍学会編集委員会
2022/06 - 現在日本放射線腫瘍学会代議員
2022/04 - 現在日本中性子捕捉療法学会薬剤評価標準化対応委員会

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Association Membership(s) (7)：

日本ハイパーサーミア学会 , 国際中性子捕捉療法学会 , 日本中性子捕捉療法学会 , Japan Society of Clinical Oncology , 国際癌治療増感研究会 , 日本医学放射線学会 , 日本放射線腫瘍学会

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