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J-GLOBAL ID:201701015571060840   Update date: Feb. 16, 2025

Ito Yutaka

イトウ ユタカ | Ito Yutaka
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Affiliation and department:
Job title: 教授
Research field  (2): Biophysics ,  Structural biochemistry
Research keywords  (4): protein dynamics ,  protein structure ,  in-cell NMR ,  NMR spectroscopy
Research theme for competitive and other funds  (28):
  • 2021 - 2024 In-situ structural biology by NMR spectroscopy
  • 2019 - 2024 In-cell NMR studies of metalloproteins
  • 2019 - 2024 Multi-scale molecular dynamics simulation on biomolecular dynamics in crowded cellular environments
  • 2017 - 2019 NMRを用いた細胞内蛋白質の立体構造,安定性および動的平衡状態の解析
  • 2013 - 2019 NMRと計算科学の融合によるin situ構造生物学の確立と真核細胞内蛋白質の動態研究への応用
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Papers (103):
  • Keita Tateno, Takami Ando, Maako Tabata, Haruka Sugasawa, Toshifumi Hayashi, Sangya Yu, Sayeesh Pm, Kohsuke Inomata, Tsutomu Mikawa, Yutaka Ito, et al. Different molecular recognition by three domains of the full-length GRB2 to SOS1 proline-rich motifs and EGFR phosphorylated sites. Chemical science. 2024. 15. 38. 15858-72
  • Takayuki Nagae, Mitsuhiro Takeda, Tomoyasu Noji, Keisuke Saito, Hiroshi Aoyama, Yohei Miyanoiri, Yutaka Ito, Masatsune Kainosho, Yuu Hirose, Hiroshi Ishikita, et al. Direct evidence for a deprotonated lysine serving as a H-bond “acceptor” in a photoreceptor protein. Proceedings of the National Academy of Sciences. 2024. 121. 36
  • Pooppadi Maxin Sayeesh, Teppei Ikeya, Haruka Sugasawa, Riki Watanabe, Masaki Mishima, Kohsuke Inomata, Yutaka Ito. Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos. Biochemical and biophysical research communications. 2022. 625. 87-93
  • Mayu Okada, Yutaka Tateishi, Eri Nojiri, Tsutomu Mikawa, Sundaresan Rajesh, Hiroki Ogasa, Takumi Ueda, Hiromasa Yagi, Toshiyuki Kohno, Takanori Kigawa, et al. Multi-state structure determination and dynamics analysis reveals a new ubiquitin-recognition mechanism in yeast ubiquitin C-terminal hydrolase. 2021
  • Takayuki Nagae, Masashi Unno, Taiki Koizumi, Yohei Miyanoiri, Tomotsumi Fujisawa, Kento Masui, Takanari Kamo, Kei Wada, Toshihiko Eki, Yutaka Ito, et al. Structural basis of the protochromic green/red photocycle of the chromatic acclimation sensor RcaE. 2020
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MISC (80):
  • 館野桂太, 菅澤はるか, 安藤孝史, 田端真彩子, 美川務, 猪股晃介, 甲斐荘正恒, 三島正規, 三島正規, 杉田有治, et al. Solution NMR analysis reveals different binding modes on the interaction between a human multi-domain protein GRB2 and human SOS1-PRMs. Abstracts. Annual Meeting of the NMR Society of Japan. 2022. 61st
  • 安藤考史, 菅澤はるか, 館野圭太, 田端真彩子, 美川務, 宮野入洋平, 川端庸平, DOKAINISH Hisham, REN Weitong, 大出真央, et al. Structure determination of a human multi-domain protein, GRB2, by paramagnetic NMR. Abstracts. Annual Meeting of the NMR Society of Japan. 2022. 61st
  • 渡邉吏輝, SAYEESH Pooppadi Maxin, 末元雄介, 木川隆則, 三島正規, 猪股晃介, 池谷鉄兵, 伊藤隆. NMR studies of a Drosophila multi-domain adaptor protein Drk. Abstracts. Annual Meeting of the NMR Society of Japan. 2020. 59th
  • 田端真彩子, 池谷鉄兵, 美川務, 川端庸平, 安藤考史, 館野桂太, 三島正規, 伊藤隆. Structural analysis of a multi-domain protein Grb2 using PRE and PCS restraints. Abstracts. Annual Meeting of the NMR Society of Japan. 2020. 59th
  • 鈴木拓巳, 田島佳寿, 川原裕之, 伊藤隆, 三島正規. Analysis of Rab32 by solution NMR. Abstracts. Annual Meeting of the NMR Society of Japan. 2020. 59th
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Education (5):
  • 1997 - University of Tokyo Graduate School of Science Ph.D.
  • 1991 - 1993 University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry
  • 1989 - 1991 University of Tokyo Graduate School of Science M.Sc., Department of Biophysics and Biochemistry
  • 1987 - 1989 University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
  • 1985 - 1987 University of Tokyo Natural Sciences I
Professional career (1):
  • 博士(理学) (東京大学)
Work history (12):
  • 2020/04 - 現在 Tokyo Metropolitan University Department of Chemistry Professor
  • 2005/04 - 現在 RIKEN Senior Visiting Scientist
  • 2005/04 - 2020/03 Tokyo Metropolitan University Department of Chemistry, Graduate School of Science Professor
  • 2005/04 - 2011/03 Yokohama City University Division of Molecular and Cellular Physiology, Science of Biological Supramolecular Systems Graduate School of Integrated Science Guest Professor
  • 2005/01 - 2005/03 RIKEN Advanced Biomolecular NMR Research Unit Unit Leader
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Association Membership(s) (7):
日本薬学会物理系薬学部会 ,  THE NUCLEAR MAGNETIC RESONANCE SOCIETY OF JAPAN ,  PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE CHEMICAL SOCIETY OF JAPAN ,  THE BIOPHYSICAL SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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