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Rchr
J-GLOBAL ID：201701016657019040
Update date: Feb. 26, 2025 Suzuki Miho
スズキ ミホ | Suzuki Miho
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National Institute for Basic Biology
About National Institute for Basic Biology
Research theme for competitive and other funds (9)：
- 2023 - 2026 ミスマッチリペア機構欠損に依存しないマイクロサテライト不安定性誘導系の研究
- 2020 - 2023 がん細胞の複製ストレスを解消する新規lncRNAの機能解明
- 2016 - 2021 DDS技術を基盤とした革新的がん治療法の開発
- 2017 - 2020 転写量ノイズを消去し細胞均一性を維持する機構の解明
- 2014 - 2017 遺伝子転写領域のクロマチン構造とエピジェネティック制御の解明
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- Keiko Shinjo, Takashi Umehara, Hideaki Niwa, Shin Sato, Keisuke Katsushima, Shinya Sato, Xingxing Wang, Yoshiteru Murofushi, Miho M. Suzuki, Hiroo Koyama, et al. Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma. Cancer Gene Therapy. 2024. 31. 12. 1884-1894
- Mayumi Oishi, Keiko Shinjo, Keisuke Takanari, Ayako Muraoka, Miho M. Suzuki, Miki Kanbe, Shinichi Higuchi, Katsumi Ebisawa, Kazunobu Hashikawa, Yuzuru Kamei, et al. Exclusive expression of KANK4 promotes myofibroblast mobility in keloid tissues. Scientific Reports. 2024. 14. 1
- Ryosuke Sonobe, Peng Yang, Miho M. Suzuki, Keiko Shinjo, Kenta Iijima, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka, Hiroaki Kajiyama, Yutaka Kondo. Long noncoding RNA TUG1 promotes cisplatin resistance in ovarian cancer via upregulation of DNA polymerase eta. Cancer Science. 2024. 115. 6. 1910-1923
- Miho M Suzuki, Kenta Iijima, Koichi Ogami, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Xuebing Wang, Yotaro Kitano, Akira Mamiya, Yuji Kibe, et al. TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation. Nature communications. 2023. 14. 1. 4521-4521
- Ayako Muraoka, Miho Suzuki, Tomonari Hamaguchi, Shinya Watanabe, Kenta Iijima, Yoshiteru Murofushi, Keiko Shinjo, Satoko Osuka, Yumi Hariyama, Mikako Ito, et al. Fusobacterium infection facilitates the development of endometriosis through the phenotypic transition of endometrial fibroblasts. Science Translational Medicine. 2023. 15. 700
- 鈴木美穂, 村岡彩子, 近藤豊. フソバクテリウム細菌感染は子宮内膜症の発症を誘導する. 医学のあゆみ. 2024. 291. 2. 143-144
- 鈴木美穂, 近藤豊. ヒストンメチル化制御阻害剤. 遺伝子医学MOOK 36号「エピゲノムで新たな解明 が進む『先天性疾患』」. 2021
- 田崎 慶彦, 勝島 啓佑, 新城 恵子, 鈴木 美穂, 飯島 健太, 宮田 完二郎, 片岡 一則, 木村 和哲, 近藤 豊. 膵臓がんにおけるLncRNA TUG1を標的とした治療の有効性の検討. 日本癌学会総会記事. 2020. 79回. OE14-2
- Operating principle of EZH2 inhibitor and current development situation. 2018. 266. 11. 834-839
- 鈴木美穂, 勝島啓佑, 近藤豊. 長鎖非コード RNA をターゲットにした膠芽腫の治療. Medical Science Digest. 2018. 44. 238-40
- マイクロバイオームと医療応用 : 全身の微生物叢が生理機能と病態をいかに制御するか? 長谷耕二/編
実験医学増刊 42(17) 31-37 羊土社 2024 ISBN:9784758104227
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Complehensive analysis of R-loop resolution unveils cooperative roles of long non-coding RNA TUG1 and DEAD/DEAH box RNA helicases
(Keystone Symposia, Non-Coding RNA Biology 2025) -
Targeted resolution of R-loops by TUG1 and RNA Helicases
(第47回日本分子生物学会年会 2024) -
Essential role of TUG1-mediated R-loop resolution in cancer cell proliferation
(Fukuoka RNA Commons / ISFRCB 2024 2024) -
Essential role of TUG1-mediated R-loop resolution in cancer cell proliferation
(17th Asian Epigenomics Meeting 2024) -
The role of lncRNA TUG1 and RNA helicases in regulation of DNA replication stress
(第83回日本癌学会学術総会 2024)
- 博士(理学) (京都大学)
- 2017/04 - 現在 名古屋大学医学系研究科 腫瘍生物学部門 助教
- 2014/04 - 2017/03 National Institute for Basic Biology
- 2013/04 - 2014/03 National Institute for Basic Biology
- 2012/04 - 2013/03 National Institute for Basic Biology
- 2009/10 - 2012/03 Institute for Developmental Research, Aichi Human Service Center
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- 2021/11 - The Japanese Biochemical Society JB reviewer award
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