2021 - 2025 How hydrogen peroxide regulate fertilization?: The elucidation of the target protein of hydrogen peroxide during fertilization.
2022 - 2024 冬眠中の心筋細胞のT管膜維持機構の解明による革新的心不予防法の創出
2015 - 2019 Can cilia of ventricular ependymal cells control flow of CSF?
2015 - 2018 Elucidation of regulatory mechanism of capacitation by extracellular Na+ in hamster spermatozoa
Papers (16):
Gen L Takei. Molecular mechanisms of mammalian sperm capacitation, and its regulation by sodium-dependent secondary active transporters. Reproductive medicine and biology. 2024. 23. 1. e12614
Gen L Takei, Yasuhiro Horibata, Fubito Toyama, Keitaro Hayashi, Asuka Morita, Motoshi Ouchi, Tomoe Fujita. Hamster spermatozoa incorporate hypotaurine via TauT for self-protection. Reproduction (Cambridge, England). 2024
Gen Takei, Yuhei Ogura, Yoshihiro Ujihara, Fubito Toyama, Keitaro Hayashi, Tomoe Fujita. Hamster Sperm Possess Functional Na+/Ca2+-Exchanger 1: Its Implication in Hyperactivation. International Journal of Molecular Sciences. 2023
Gen L Takei. [Regulation of sperm hyperactivation by transporters involved in Na+ homeostasis]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 2022. 157. 3. 176-180
Gen L. Takei, Darya A. Tourzani, Bidur Paudel, Pablo E. Visconti. Activation of cAMP-dependent phosphorylation pathways is independent of ROS production during mouse sperm capacitation. MOLECULAR REPRODUCTION AND DEVELOPMENT. 2021
Gen L. Takei, Horibata Yasuhiro, Toyama Fubito, Hayashi Keitaro, Morita Asuka, Ouchi Motoshi, Fujita Tomoe. Antioxidant mechanisms of hypotaurine by an action of taurine transporter (TauT) in hamster sperm. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2023. 97. 1-B-O02-1
竹井 元, 藤田 朋恵. 精子におけるNa+/K+ATPase各アイソフォームの、ouabainを用いた薬理学的機能解析. Dokkyo Journal of Medical Sciences. 2021. 48. 2. 124-124
Pharmacological analysis of the regulatory mechanisms of sperm hyperactivation by ouabain.
(The 94th Annual Meeting of the Japanese Pharmacological Society 2021)
Education (2):
2007 - 2012 東京大学大学院 総合文化研究科広域科学専攻生命環境科学系
2003 - 2007 The University of Tokyo College of Arts and Sciences
Professional career (1):
博士(学術) (東京大学)
Work history (5):
2023/12 - 現在 Dokkyo Medical University Department of pharmacology and toxicology Lecturer
2020/04 - 2023/11 Dokkyo Medical University Department of Pharmacology and Toxicology Assistant Professor
2013/04 - 2020/03 Dokkyo Medical University Depatment of Regulatory Physiology Assistant Professor
2018/04 - 2019/04 University of Massachusetts, Amherst Department of Veterinary and Animal Sciences Visiting scholar