Research theme for competitive and other funds (2):
2020 - 2023 Novel cancer radiation therapy employing monochromatic X-rays and nanoparticles
2017 - 2019 Novel Boron containing Nanoparticles and their application in BNCT.
Papers (139):
Mathilde Laird, Kotaro Matsumoto, Yuya Higashi, Aoi Komatsu, Art Raitano, Kendall Morrison, Minoru Suzuki, Fuyuhiko Tamanoi. Organosilica nanoparticles containing sodium borocaptate (BSH) provide new prospects for boron neutron capture therapy (BNCT): efficient cellular uptake and enhanced BNCT efficacy. Nanoscale advances. 2023. 5. 9. 2537-2546
Yuya Higashi, Shuji Ikeda, Kotaro Matsumoto, Shinsuke Satoh, Aoi Komatsu, Hiroshi Sugiyama, Fuyuhiko Tamanoi. Tumor Accumulation of PIP-Based KRAS Inhibitor KR12 Evaluated by the Use of a Simple, Versatile Chicken Egg Tumor Model. Cancers. 2022. 14. 4. 951-951
Yuya Higashi, Kotaro Matsumoto, Hiroyuki Saitoh, Ayumi Shiro, Yue Ma, Mathilde Laird, Shanmugavel Chinnathambi, Albane Birault, Tan Le Hoang Doan, Ryo Yasuda, et al. Iodine containing porous organosilica nanoparticles trigger tumor spheroids destruction upon monochromatic X-ray irradiation: DNA breaks and K-edge energy X-ray. Scientific Reports. 2021. 11. 1
Aoi Komatsu, Kotaro Matsumoto, Yuki Yoshimatsu, Yooksil Sin, Arisa Kubota, Tomoki Saito, Ayaka Mizumoto, Shinya Ohashi, Manabu Muto, Rei Noguchi, et al. The CAM Model for CIC-DUX4 Sarcoma and Its Potential Use for Precision Medicine. Cells. 2021. 10. 10
Miguel Gisbert-Garzaran, Daniel Lozano, Kotaro Matsumoto, Aoi Komatsu, Miguel Manzano, Fuyuhiko Tamanoi, Maria Vallet-Regi. Designing Mesoporous Silica Nanoparticles to Overcome Biological Barriers by Incorporating Targeting and Endosomal Escape. ACS Applied Materials and Interfaces. 2021. 13. 8. 9656-9666
James B. Finlay, Cai M. Roberts, Gina Lowe, Ling Peng, Jeff I. Zink, Fuyuhiko Tamanoi, Carlotta A. Glackin. Treatment of metastatic breast cancer using two nanoparticles combined with siRNA targeting Twist1 to inhibit EMT. CANCER RESEARCH. 2015. 75
Fariborz (Fred) Mortazavi, Jie Lu, Aljilani Amir, Ryan Phan, Fuyuhiko Tamanoi. Interruption of K-Ras/PAK1/Crk pathway has a dramatic anti-tumor effect in NSCLC. MOLECULAR CANCER RESEARCH. 2014. 12
Jie Lu, Jonas Croissant, Jean-Olivier Jean-Olivier Durand, Tania Guardado-Alvarez, Jeffrey I. Zink, Fuyuhiko Tamanoi. Light-controllable nano-drug delivery system with deep tissue penetrating ability for cancer therapy with two-photon-triggered nanoimpellers. CANCER RESEARCH. 2014. 74. 19
Jeffrey J. Heard, Valerie Fong, S. Zahra Bathaie, Fuyuhiko Tamanoi. Recent progress in the study of the Rheb family GTPases. CELLULAR SIGNALLING. 2014. 26. 9. 1950-1957
Gadolinium-loaded mesoporous silica nanoparticles trigger destruction of tumor spheroids upon irradiation with monochromatic X-ray
(The 8th Japan-China Symposium on Nanomedicine 2021)
A new radiation therapy by combining gadolinium-loaded nanoparticles and monochromatic X-ray
(E-MRS Spring meeting 2021 2021)
量子ビームとナノ材料研究により拓かれる量子ナノ医療研究
(ナノ学会第18回大会 2020)
Nanomedicine and Cancer Therapy
(Kyoto University-Academia Sinica Bilateral Symposium 2019)
Novel radiation therapy employing monochromatic X-ray and nanoparticles
(First QNM-iCeMS Symposium: Exploring New Approaches for Cancer Therapy 2019)