Rchr
J-GLOBAL ID:201701019952623722
Update date: Feb. 01, 2024
Kubori Tomoko
Kubori Tomoko | Kubori Tomoko
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
https://sites.google.com/view/nagai-lab/home
Research field (1):
Molecular biology
Research keywords (8):
ubiquitin
, molecular structure
, electron microscopy
, host pathogen interaction
, virulence
, effector proteins
, secretion systems
, bacteria
Research theme for competitive and other funds (18):
- 2023 - 2027 細菌の感染戦略が切り拓く新規ユビキチン制御機構の解明
- 2022 - 2025 病原細菌によるユビキチンシステムを介したオルガネラ膜動態の制御
- 2019 - 2022 Bacterial pathogen-mediated tiered regulations on the host ubiquitin system
- 2021 - 細菌の感染戦略が切り拓く新規ユビキチン制御機構の解明
- 2019 - 細菌の感染戦略が切り拓く新規ユビキチン制御機構の解明
- 2016 - 2019 Analysis of bacterial effector proteins that negatively regulate the host ubiquitin system
- 2016 - 2019 The possibility of lipid-ubiquitin conjugation associated with xenophagy
- 2015 - 2017 病原性 IV 型分泌マシナリーの全構造解析
- 2014 - 2016 Molecular basis of evasion of Legionella from xenophagy
- 2013 - 2016 Structural analysis and assembly pathway of the pathogenic bacterial type IVB secretion system transport channel
- 2007 - 2008 レジオネラエフェクターと宿主因子の相互作用とその機能
- 2007 - 2008 Molecular analyses of a Legionella ubiquitin ligase.
- 2006 - 2007 レジオネラによるファゴソーム改変の分子機構
- 2006 - 2007 レジオネラIV型分泌装置の構造形成と作動機構
- 2006 - 2007 Functional analysis of Legionella Dot/Icm T4SS component DotA.
- 2005 - 2006 Molecular analysis of the Legionella typeIV secretion system
- 2005 - 2005 レジオネラ膜タンパク質DotAのIV型分泌系による輸送機構の解析
- 1996 - 1997 TYPE III EXPORT SYSTEM ; STRUCTURAL ANALYSIS OF FLAGELLA-SPECIFIC EXPORT APPARATUS OF BACTERIA
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Papers (61):
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Tomoko Kubori. A two-component system serves as a central hub for connecting energy metabolism and plasmid dissemination in bacteria. mBio. 2023. 14. 6. e0247423
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Tomoko Kubori, Kohei Arasaki, Tomoe Kitao, Hiroki Nagai. Multi-tiered actions of Legionella effectors to modulate host Rab10 dynamics. eLife. 2023
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Jonathan N. Pruneda, Justine V. Nguyen, Hiroki Nagai, Tomoko Kubori. Bacterial usurpation of the OTU deubiquitinase fold. The FEBS Journal. 2023
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Gus D. Warren, Tomoe Kitao, Tyler G. Franklin, Justine V. Nguyen, Paul P. Geurink, Tomoko Kubori, Hiroki Nagai, Jonathan N. Pruneda. Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA. Molecular Cell. 2023. 83. 1. 105-120.e5
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Shoichi Mitsunaka, Kohei Yamazaki, Ajeng K. Pramono, Megumi Ikeuchi, Tomoe Kitao, Naoya Ohara, Tomoko Kubori, Hiroki Nagai, Hiroki Ando. Synthetic engineering and biological containment of bacteriophages. Proceedings of the National Academy of Sciences. 2022. 119. 48
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MISC (11):
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北尾公英, 久堀智子, 永井宏樹. 病原細菌レジオネラによるユビキチンを介した宿主小胞輸送システムの操作. 生化学. 2021. 93. 6
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久堀智子, 北尾公英, 永井宏樹. レジオネラ病原因子輸送系の構造と機能. 生物物理. 2019. 59. 341. 014-017
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平安 恒幸, 齋藤 史路, 末永 忠広, 信田 京子, 荒瀬 規子, 及川 敬太, 山岡 俊文, 室田 浩之, 知花 博治, 中川 一路, et al. HLAクラスI認識受容体群LILRの新展開 病原微生物によって壊された抗体を認識する生体防御機構. MHC: Major Histocompatibility Complex. 2016. 23. 2Suppl. 95-95
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平安 恒幸, 齋藤 史路, 末永 忠広, 信田 京子, 荒瀬 規子, 及川 敬太, 山岡 俊文, 室田 浩之, 知花 博治, 中川 一路, et al. HLAクラスI認識受容体群LILRの新展開 病原微生物によって壊された抗体を認識する生体防御機構. MHC: Major Histocompatibility Complex. 2016. 23. 2Suppl. 95-95
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平安恒幸, 齋藤史路, 末永忠広, 末永忠広, 信田京子, 荒瀬規子, 荒瀬規子, 及川敬太, 山岡俊文, 室田浩之, et al. HLAクラスI認識受容体群LILRの新展開-病原微生物によって壊された抗体を認識する生体防御機構-. MHC (Web). 2016. 23. 2 Suppl
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Books (3):
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Hijacking the host proteasome for the temporal degradation of bacterial effectors.
Methods Mol Biol Vol.1197 2014
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Modulation of the Ubiquitination Machinery by Legionella
Molecular Mechanisms in Legionella Pathogenesis 2013
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Purification and characterization of legionella u-box-type e3 ubiquitin ligase.
Methods Mol Biol Vol.954 2013
Lectures and oral presentations (48):
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Reversible modification of mitochondrial ADP/ATP translocases by paired Legionella effector proteins
(The 96th Annual Meeting of Japanese Society for Bacteriology 2023)
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Reversible modification of mitochondrial ADP/ATP translocases by paired Legionella effector proteins
(The 10th International Conference on Legionella 2022)
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Legionella manipulates non-canonical SNARE pairing by the function of a bacterial deubiquitinase
(The 18th Awaji International Forum on Infection and Immunity 2019)
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Manipulation of the host ubiquitin system by Legionella
(Cold Spring Harbor Asia Conference on Bacterial Infection and Host Defense 2019)
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PLOS Pathogens Writing Workshop
(14th Rencontres du Vietnam "Innovative Approaches to the Study of Bacterial Pathogens" 2018)
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Professional career (1):
Work history (1):
- 2017/05 - 現在 Gifu University Department of Microbiology Associate Professor
Committee career (5):
- 2022/10 - 現在 Frontiers in Cellular and Infection Microbiology Guest Editor
- 2012/01 - 現在 PLOS Pathogens Associate Editor
- 2022/07 - 2023/06 日本学術振興会 特別研究員等審査会専門委員
- 2017/12 - 2020/11 科学研究費委員会専門委員
- 2010/12 - 2012/11 科学研究費委員会専門委員
Association Membership(s) (2):
THE BIOPHYSICAL SOCIETY OF JAPAN
, JAPANESE SOCIETY FOR BACTERIOLOGY
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