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J-GLOBAL ID：201701020461465511 Update date: Feb. 25, 2025

Yamazaki Sayuri

ヤマザキサユリ | Yamazaki Sayuri

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Affiliation and department：
Job title： Professor and Chairman
Homepage URL (1)： http://www.med.nagoya-cu.ac.jp/immunol.dir/

Research field (3)： Immunology , Dermatology , Experimental pathology

Research keywords (6)： regulatory T cell , dendritic cell , Immune regulation, immunological tolerance , skin immunity , homeostasis of tissue, regeneration , tumor immunity, head and neck cancer

Research theme for competitive and other funds (40)：

2021 - 2024 Pioneering of the unique treatment strategy and optical science by proenkephalin+ reguratory Tcells
2021 - 2024 制御性T細胞と樹状細胞のバランスによる免疫系・生体恒常性制御機構の解明と新規免疫療法・再生療法への挑戦
2022 - 2023 制御性T細胞がつくるプロエンケファリンを利用した新たな医療開発
2020 - 2023 Mechanisms of immune regulation by DC-Treg crosstalk
2019 - 2023 Mechanisms of autoimmune diseases triggered by infectious foci and treatment strategies

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Papers (57)：

Hiroaki Shime, Mizuyu Odanaka, Masaki Imai, Daisuke Sugiyama, Shoryu Takayama, Akimichi Morita, Sayuri Yamazaki. Ultraviolet-B irradiation expands skin-resident CD81+Foxp3+ regulatory T cells with a highly activated phenotype. Journal of Investigative Dermatology. 2024
Sayuri Yamazaki. Diverse roles of dendritic cell and regulatory T cell crosstalk in controlling health and disease. International Immunology. 2024. in press
Kiyoshi Minohara, Masaki Imai, Takuma Matoba, James Badger Wing, Hiroaki Shime, Mizuyu Odanaka, Ryuta Uraki, Daisuke Kawakita, Tatsuya Toyama, Satoru Takahashi, et al. Mature dendritic cells enriched in regulatory molecules may control regulatory T cells and the prognosis of head and neck cancer. Cancer science. 2022. 114. 4. 1256-1269
Ryuta Uraki, Masaki Imai, Mutsumi Ito, Hiroaki Shime, Mizuyu Odanaka, Moe Okuda, Yoshihiro Kawaoka, Sayuri Yamazaki. Foxp3+ CD4+ regulatory T cells control dendritic cells in inducing antigen-specific immunity to emerging SARS-CoV-2 antigens. PLoS Pathogens. 2021. 17. 12. e1010085-e1010085
Yoichi Shintani, Emi Nishida, Takuya Furuhashi, Shinnosuke Muramatsu, Ryoji Kubo, Motoki Nakamura, Shoichi Watanabe, Hideyuki Masuda, Kyoko Ikumi, Kazuhiko Matsumoto, et al. Efficacy of bath-psoralen and ultraviolet A therapy for mycosis fungoides - retrospective analysis of 62 cases. Journal of Dermatology. 2021. 49. 2. 239-245

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Patents (2)：

Dendritic cell expanded T suppressor cells and methods of use thereof
Culture Expanded T Suppressor Cells and Methods of Use

Books (29)：

腫瘍微少環境における樹状細胞ー制御性T細胞クロストーク
臨床免疫・アレルギー科科学評論社 2024
もっとよくわかる!腫瘍免疫学(西川博嘉編)
実験医学別冊羊土社 2023
制御性T細胞の解析ーその歴史からフローサイトメーター解析時の注意点までー
皮膚科科学評論社 2022
乾癬とアトピー性皮膚炎の病態と免疫制御
皮膚病診療協和企画 2021
皮膚の恒常性維持と制御性T細胞
臨床免疫・アレルギー科科学評論社 2021

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Lectures and oral presentations (57)：

Ultraviolet B exposure controls skin homeostasis by dendritic cell-regulatory T cell crosstalk
(The 49th Annual Meeting of the Japanese Society for Investigative Dermatology 2024)
Regulatory T cell-dendritic cell crosstalk as controllers of health and disease
(The 52nd Annual Meeting of The Japanese Society for Immunology 2024)
Immune regulation mediated by crosstalk between dendritic cells and regulatory T cells
(The 5th CSI/JSI/KAI Joint Symposium on Immunology 2024)
Divers roles of Treg-DC crosstalk in regulation of immunity
(WMU and NTU Joint Seminar 2023)
頭頸部がんのユニークな微小免疫環境
(第39回日本皮膚悪性腫瘍学会学術大会 2023)

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Education (3)：

1991 - 1995 Tokyo Medical and Dental University, Graduate School of Medical School (PhD) Department of Dermatology
1985 - 1991 Tokyo Medical and Dental University (MD) Medical School
1982 - 1985 Tokyo Gakugei University Senior High School

Professional career (2)：

Ph.D (Tokyo Medical and Dental University)
M.D. (Tokyo Medical and Dental University)

Work history (10)：

2014/12 - 現在 Nagoya City University, Graduate School of Medical Sciences, Department of Immunology, Professor and Chairman
2012/04 - 2014/11 Nagoya City University, Graduate School of Medical Sciences, Department of Geriatric and Environmental Dermatology, Associate professor
2011/04 - 2012/03 Tokyo Medical and Dental University, Department of dermatology, Visiting Lecturer
2011/04 - 2012/03 Dokkyo Medical University, Koshigaya Hospital, Dermatology, Associate professor/Lecturer
2009/07 - 2011/03 Hokkaido University, Graduate school of Medicine, Department of Immunology, Specifically Appointed Associate Professor

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Committee career (20)：

2024/01 - 現在 Japaese Society for Immunology Chairperson of Election Administration Committee
2020/06 - 現在 Nagoya City University Institutional Review Board (IRB)
2019/06 - 現在 International Medical Research Foundation Academic committee
2017/12 - 現在 Frontiers in Immunology Review Editor
2017/05 - 現在 Journal of Experimental Medicine (J Exp Med) Advisory Editorial Board

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Awards (10)：

2022 - The 9st Japanese Society for Immunology Women Immunologist Award
2016 - Japan Rheumatism Foundation Minako Shiokawa Young Investigator’s Award for Collagen Disease Research Japan Rheumatism Foundation
2015 - 平成27年度加齢皮膚医学研究基金ロート賞
2008 - 10th International Symposium on Dendritic Cells Travel Award,
2008 - International Investigative Dermatology Travel Award,

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Association Membership(s) (12)：

Association for Cancer Immunotherapy (CIMT) , The American Association of Immunologists , THE JAPAN SOCIETY FOR CLINICAL IMMUNOLOGY , The Japanese Society of Interferon & Cytokine Research , THE JAPANESE DERMATOLOGICAL ASSOCIATION , THE JAPANESE SOCIETY FOR INVESTIGATIVE DERMATOLOGY , THE JAPANESE SOCIETY FOR IMMUNOLOGY , The Japanese Society for Molecular Cell Biology of Macrophages , 日本樹状細胞研究会 , The Japan Cancer Association , American Association for the Advancement of Science , Society for Investigative Dermatology

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