Furukawa Ayako

フルカワアヤコ | Furukawa Ayako

Homepage URL (1)： https://researchmap.jp/a_a

Research field (1)： Structural biochemistry

Research keywords (1)：構造生物学

Research theme for competitive and other funds (10)：

2023 - 2025 クロマトソーム中のヒストンテイルとDNA間の動的相互作用解析
2021 - 2024 液液相分離したリン酸化HP1αのヌクレオソーム結合への機能解明
2021 - 2023 Elucidation of dynamic interactions of histone tails with nucleosomal DNA or linker DNA
2017 - 2021 リアルタイムNMRによるDNAメチル化酵素の作用機序の解明
2015 - 2017 インプリント遺伝子のDNAメチル化模様を制御するDnmt3aの過渡的複合体

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Papers (35)：

Kosuke Sako, Ayako Furukawa, Ryu-Suke Nozawa, Jun-Ichi Kurita, Yoshifumi Nishimura, Toru Hirota. Bipartite binding interface recruiting HP1 to chromosomal passenger complex at inner centromeres. The Journal of cell biology. 2024. 223. 9
Hideaki Ohtomo, Shinsuke Ito, Nicholas J. McKenzie, Michael Uckelmann, Masatoshi Wakamori, Haruhiko Ehara, Ayako Furukawa, Yasuo Tsunaka, Marika Shibata, Shun-ichi Sekine, et al. H2A ubiquitination alters H3-tail dynamics on linker-DNA to enhance H3K27 methylation. Journal of Molecular Biology. 2023. 167936-167936
Yasuo Tsunaka, Ayako Furukawa, Yoshifumi Nishimura. Histone tail network and modulation in a nucleosome. Current opinion in structural biology. 2022. 75. 102436-102436
Ayako Furukawa, Masatoshi Wakamori, Yasuhiro Arimura, Hideaki Ohtomo, Yasuo Tsunaka, Hitoshi Kurumizaka, Takashi Umehara, Yoshifumi Nishimura. Characteristic H3 N-tail dynamics in the nucleosome core particle, nucleosome, and chromatosome. iScience. 2022. 25. 3. 103937-103937
Ayako Furukawa, Erik Walinda, Kyohei Arita, Kenji Sugase. Structural dynamics of double-stranded DNA with epigenome modification. Nucleic acids research. 2020. 49. 2. 1152-1162

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MISC (39)：

Nagpal Harsh, 堀哲也, Furukawa Ayako, 菅瀬謙治, 越阪部晃永, 胡桃坂仁志, 深川竜郎. 細胞周期中のCCANの構成の動的な変化(Dynamic Change of CCAN organization during the cell cycle). 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [2T23-13(2P0113)]
Kanba, K, Furukawa, A, Sugase, K, Nagata, T, Katahira, M. Deamination mechanism of an anti-HIV APOBEC3G coupled with sliding on single-stranded DNA as analyzed by real-time NMR monitoring method. The 41st International Symposium on Nucleic Acids Chemistry. 2014
Kanba, K, Mashima, T, Okamura, H, Furukawa, A, Sugase, K, Nishimura, H, Watanabe, T, Nagata, T, Katahira, M. Real-time NMR monitoring of enzymatic reaction of anti-HIV protein, structure of anti-prion RNA aptamer and wood biomass analysis. The 5th Japan-Taiwan NMR symposium. 2014
Kanba, K, Furukawa, A, Sugase, K, Morishita, R, Nagata, T, Katahira, M. Functional mechanism of an anti-HIV protein, APOBEC3G, as revealed by real-time NMR monitoring of its enzymatic reaction. XXVIth International Conference on Magnetic Resonance in Biological Systems. 2014
K. Kanba, A. Furukawa, K. Sugase, R. Morishita, T. Nagata, M. Katahira. Functional mechanism of anti-HIV protein, APOBEC3G, elucidated by real-time monitoring of enzymatic reaction, and anti-prion activity of an RNA aptamer with its structural basis. The 45th Annual Meeting of Korean Magnetic Resonance Society. 2014

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Patents (1)：

Books (1)：

Awards (2)：

Association Membership(s) (1)：

日本生物物理学会

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