Rchr
J-GLOBAL ID:201801000760266777   Update date: Jul. 04, 2024

KOGA Takayuki

KOGA Takayuki
Affiliation and department:
Research field  (4): Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - health and biochemistry
Research keywords  (6): 脂質代謝 ,  非アルコール性脂肪肝 ,  metabolome analysis ,  amino acid metabolism ,  nuclear receptor ,  dermatitis
Research theme for competitive and other funds  (5):
  • 2024 - 2027 亜硫酸由来ラジカル産生の制御に基づく潰瘍性大腸炎創薬基盤の創成
  • 2019 - 2022 Creation of a novel dermatitis treatment strategy with Selenbp1
  • 2017 - 2018 アトピー性皮膚炎におけるアミノ酸補給療法の有効性の 検討
  • 2017 - 2018 アレルギー性接触皮膚炎治療法としての恒常的なメチオニン摂取の有用性の評価
  • 2015 - 2016 乳酸菌によるアトピー性皮膚炎発症制御機構の解析
Papers (29):
  • Takayuki Koga, Kie Inoue, Fuka Hirayama, Makoto Hiromura, Kiyonaga Fujii, Yuji Ishii, Masayo Hirao-Suzuki, Shuso Takeda, Akihisa Toda, Fumio Soeda. Dimethylglycine, a methionine metabolite, participates in the suppressive effect of methionine on 1-fluoro-2,4-dinitrobenzene-induced dermatitis. Biological & pharmaceutical bulletin. 2023. 46. 7. 946-954
  • Syota Kagawa, Katsuya Tanabe, Makoto Hiromura, Kakuyou Ogawa, Takayuki Koga, Takahiro Maeda, Kikuko Amo-Shiinoki, Hiroyuki Ochi, Yui Ichiki, Shogo Fukuyama, et al. Hachimijiogan, a traditional herbal medicine, modulates adipose cell function and ameliorates diet-induced obesity and insulin resistance in mice. Frontiers in Pharmacology. 2023. 14
  • Ming Yuan, Hiroe Sano, Takaaki Nishino, Hongbin Chen, Ren-Shi Li, Yuki Matsuo, Kyoko Nishida, Takayuki Koga, Tomoki Takeda, Yoshitaka Tanaka, et al. α-Lipoic acid eliminates dioxin-induced offspring sexual immaturity by improving abnormalities in folic acid metabolism. Biochemical pharmacology. 2023. 210. 115490-115490
  • Masayo Hirao-Suzuki, Koga Takayuki, Masufumi Takiguchi, Jeffrey M Peters, Shuso Takeda. Cannabidiolic acid activates the expression of the PPARβ/δ target genes in MDA-MB-231 cells. Archives of Biochemistry and Biophysics. 2022. 731. 109428-109428
  • Genki Sakai, Masayo Hirao-Suzuki, Takayuki Koga, Takananobu Kobayashi, Jun Kamishikiryo, Michitaka Tanaka, Kiyonaga Fujii, Masufumi Takiguchi, Narumi Sugihara, Akihisa Toda, et al. Perfluorooctanoic acid (PFOA) as a stimulator of estrogen receptor-negative breast cancer MDA-MB-231 cell aggressiveness: Evidence for involvement of fatty acid 2-hydroxylase (FA2H) in the stimulated cell migration. The Journal of Toxicological Sciences. 2022. 47. 4. 159-168
more...
MISC (31):
  • 藤本茉奈, 佐野宏江, LI Ren-Shi, LI Ren-Shi, CHEN Hong-Bin, 古賀貴之, 武田知起, 武田知起, 田中嘉孝, 石井祐次. Epigenetic effects of maternal exposure to TCDD. 衛生薬学・環境トキシコロジー講演要旨集. 2022. 2022
  • 平尾雅代, 境絃樹, 古賀貴之, 田中満崇, 杉原成美, 瀧口益史, 竹田修三. PPARα-mediated regulation mechanisms of fatty acid 2-hydroxylase (FA2H) expression in MDA-MB-231 cells. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 古賀貴之, 廣村信, 平尾雅代, 竹田修三, 石田卓已, 石井祐次, 小武家優子, 戸田晶久, 副田二三夫. Hepatic Bhmt regulates suppressive effect of methionine on chemical-induced dermatitis. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 藤本茉奈, 佐野宏江, LI Ren-Shi, LI Ren-Shi, CHEN Hong-Bin, 古賀貴之, 武田知起, 武田知起, 田中嘉孝, 石井祐次. Maternal exposure to TCDD elicits disruption of fatty acid metabolism in fetal hypothalamus: possible mechanism involved in the reduced steroidogenesis. 衛生薬学・環境トキシコロジー講演要旨集. 2021. 2021
  • MING Yuan, 佐野宏江, 西田恭子, 西野隆晃, 古賀貴之, 武田知起, 武田知起, 田中嘉孝, 石井祐次. α-Lipoic acid ameliorates maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin-produced toxicity in the next generation: recovery effect of α-lipoic acid on sexual immaturity in both male and female offsprings. 衛生薬学・環境トキシコロジー講演要旨集. 2021. 2021
more...
Lectures and oral presentations  (14):
  • Analysis of strain difference in suppressive effects of amino acid supplementation to chemical-induced dermatitis
    (2018)
  • アトピー性皮膚炎発症・進行過程におけるアミノ酸補給療法の有効性の評価
    (日本薬学会 第138年会 2018)
  • Effects of amino acid supplementation on development of chemical-induced dermatitis.
    (2017)
  • アトピー性皮膚炎重症化における皮膚-肝連関の解析
    (日本薬学会 第137年会 2017)
  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin の胎児視床下部-下垂体-性腺系への障害とその回復:メタボロームとエネルギー産生系を中心とした解析
    (日本薬学会九州支部大会 2011)
more...
Education (1):
  • 2009 - 2012 Kyushu university
Professional career (1):
  • 博士(薬学) (九州大学)
Work history (4):
  • 2022/04 - 現在 Daiichi University, College of Pharmaceutical Sciences
  • 2014/04 - 2022/03 Daiichi university of pharmacy hygienic chemistry Assistant professor
  • 2012/06 - 2014/03 Pennsylvania State university the center of molecular toxicology and carcinogenesis Postdoctoral fellow
  • 2012/04 - 2012/06 kyushu university the laboratory of molecular life sciences research associate
Awards (2):
  • 2011/10 - The Pharmaceutial Society of Japan, Division of pharmaceutical health sciences and environmental toxicology Excellent Young Investigator Award
  • 2008/12 - The Pharmaceutial Society of Japan, kyushu branch Best presentation award
Association Membership(s) (2):
THE JAPANESE BIOCHEMICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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