Research theme for competitive and other funds (6):
2019 - 2022 generation of inner ear supporting cells from human iPS cells
2018 - 2022 Hair bundle formation and tonotopy in genetic hearing loss models and the iPS cells
2017 - 2020 generation of functional CX26 gap junction forming cell derived from mouse iPS cells and its application to hereditary deafness
2016 - 2018 Stem cell homing for inner ear cell therapy with iPS cell
2015 - 2017 Generation of inner ear cells from mouse iPS cells and its application to Age-related hearing loss
進行中の研究課題・終了した研究課題
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Papers (12):
Ichiro Fukunaga, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Cheng Chen, Kyoko Shirai, Atsushi Kawano, Katsuhisa Ikeda, Kazusaku Kamiya. Modeling gap junction beta 2 gene-related deafness with human iPSC. Human molecular genetics. 2021. 30. 15. 1429-1442
Ichiro Fukunaga, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Cheng Chen, Madoka Iizumi, Takahiro Shiga, Rina Matsuoka, Takashi Anzai, Remi Hibiya-Motegi, et al. Generation of two iPSC lines from siblings of a homozygous patient with hearing loss and a heterozygous carrier with normal hearing carrying p.G45E/Y136X mutation in GJB2. Stem cell research. 2021. 53. 102290-102290
Ichiro Fukunaga, Yoko Oe, Cheng Chen, Keiko Danzaki, Sayaka Ohta, Akito Koike, Katsuhisa Ikeda, Kazusaku Kamiya. Activin/Nodal/TGF-β Pathway Inhibitor Accelerates BMP4-Induced Cochlear Gap Junction Formation During in vitro Differentiation of Embryonic Stem Cells. Frontiers in cell and developmental biology. 2021. 9. 602197-602197