Rchr
J-GLOBAL ID:201801000938605511   Update date: Jul. 03, 2020

Shintaku Hirofumi

Shintaku Hirofumi
Homepage URL  (1): https://www.hshintaku.com/
Research field  (1): Fluid engineering
Research keywords  (4): RNA ,  Microfluidics ,  MEMS ,  Fluid Engineering
Research theme for competitive and other funds  (9):
  • 2014 - 2019 Micro and nano electroporation for direct delivery of molecules to cell nucleus
  • 2014 - 2017 Double-face culture system for application of alveolar epithelial cells induced from human iPS cells
  • 2014 - 2017 Simultaneous extraction and analyses of RNA and DNA from single cells
  • 2010 - 2015 Development of scientific principles on quantum molecular dynamics in confined nano-spaces
  • 2010 - 2014 Visualization techniques for electrokinetic flow dynamics in confined nanospace
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Papers (61):
  • Mahmoud N Abdelmoez, Yusuke Oguchi, Yuka Ozaki, Ryuji Yokokawa, Hidetoshi Kotera, Hirofumi Shintaku. Distinct Kinetics in Electrophoretic Extraction of Cytoplasmic RNA from Single Cells. Analytical chemistry. 2020. 92. 1. 1485-1492
  • Taikopaul Kaneko, Ken'ya Furuta, Kazuhiro Oiwa, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa. Different motilities of microtubules driven by kinesin-1 and kinesin-14 motors patterned on nanopillars. Science advances. 2020. 6. 4. eaax7413
  • Tamanna Ishrat Farhana, Tomohiro Nakagawa, Shumpei Ohara, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa. Spatial Patterning of Kinesin-1 and Dynein Motor Proteins in an In Vitro Assay using Aqueous Two-Phase Systems (ATPS). Langmuir : the ACS journal of surfaces and colloids. 2019. 35. 40. 13003-13010
  • Taikopaul Kaneko, Suguru Ando, Ken'ya Furuta, Kazuhiro Oiwa, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa. Transport of microtubules according to the number and spacing of kinesin motors on gold nano-pillars. Nanoscale. 2019. 11. 20. 9879-9887
  • Kazuya Fujimoto, Yuki Morita, Ryota Iino, Michio Tomishige, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa. Simultaneous Observation of Kinesin-Driven Microtubule Motility and Binding of Adenosine Triphosphate Using Linear Zero-Mode Waveguides. ACS nano. 2018. 12. 12. 11975-11985
more...
MISC (33):
  • Yuki Morita, Kazuya Fujimoto, Ryota Iino, Michio Tomishige, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa. Single-molecule fluorescence imaging of kinesin using linear zero-mode waveguides. Proceedings of IEEE Sensors. 2017
  • Kazuya Fujimoto, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa. TRANSITION OF Q-DOT DISTRIBUTION ON MICROTUBULE ARRAY ENCLOSED BY PDMS SEALING FOR AXONAL TRANSPORT MODEL. 2014 IEEE 27TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS). 2014. 1107-1110
  • S. P. Subramaniyan, M. C. Tarhan, S. L. Karsten, H. Fujita, H. Shintaku, H. Kotera, R. Yokokawa. DETECTION OF MUTATIONS IN THE BINDING DOMAIN OF TAU PROTEIN BY KINESIN-MICROTUBULE GLIDING ASSAY. 2014 IEEE 27TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS). 2014. 314-317
  • Nagendra Kumar Kamisetty, Junya Ikuta, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa, Ryuji Yokokawa. Manipulation of microtubles motility using electrical filed on kiensin/dynein coated surfaces. 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. 2013. 2. 811-813
  • Junya Ikuta, Nagendra K. Kamisetty, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa, Ryuji Yokokawa. Microtubule gliding at the boundary of kinesin and dynein patterned surface. 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. 2013. 3. 1454-1456
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Lectures and oral presentations  (75):
  • Development of image analysis with nanometer resolution for evaluation of the flexural rigidity and the growth rate of microtubules
    (「センサ・マイクロマシンと応用システム」シンポジウム論文集 電気学会センサ・マイクロマシン部門 [編] 2017)
  • Development of a nano-patterning of motor proteins by integration of Au nano-pillars and SAM
    (「センサ・マイクロマシンと応用システム」シンポジウム論文集 電気学会センサ・マイクロマシン部門 [編] 2017)
  • Selective immobilization of different motor proteins by using Aqueous Two-Phase System(ATPS)
    (「センサ・マイクロマシンと応用システム」シンポジウム論文集 電気学会センサ・マイクロマシン部門 [編] 2017)
  • Evaluation of Angiogenesis on 3D Vasculature through Detection and Transduction of Shear Stress
    (「センサ・マイクロマシンと応用システム」シンポジウム論文集 電気学会センサ・マイクロマシン部門 [編] 2017)
  • Single molecule observation of fluorescent labelled ATP in microtubule gliding motility using LZMWs
    (「センサ・マイクロマシンと応用システム」シンポジウム論文集 電気学会センサ・マイクロマシン部門 [編] 2017)
more...
Education (2):
  • 2002 - 2006 Kyoto University Graduate School of Engineering Mechanical Engineering
  • 1998 - 2002 Kyoto University Faculty of Engineering Mechanical Engineering
Professional career (1):
  • Dr. Eng (Kyoto University)
Work history (5):
  • 2018/04 - 現在 RIKEN RIKEN Hakubi Team Leader
  • 2012/04 - 2018/03 Kyoto University Assistant Professor
  • 2007/04 - 2012/03 Osaka University Assistant Professor
  • 2006/10 - 2007/03 Osaka University Research Associate
  • 2004/04 - 2006/10 JSPS Research Fellow
Association Membership(s) (3):
THE BIOPHYSICAL SOCIETY OF JAPAN ,  THE INSTITUTE OF ELECTRICAL ENGINEERS OF JAPAN ,  THE JAPAN SOCIETY OF MECHANICAL ENGINEERS
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