Satoh Akiko

サトウアキコ | Satoh Akiko

Affiliation and department：
Job title： Associate Professor
Other affiliations (1)：

Tohoku University Institute of Development, Aging and Cancer Department of Integrative Physiology Associate Professor

Research field (3)： Molecular biology , Neuroscience - general , Evolutionary biology

Research keywords (8)：栄養・睡眠負荷 , Caloric restriction , Epigenome , Transcription factor , Sleep , Hypothalamus , Longevity , Aging

Research theme for competitive and other funds (8)：

2022 - 2027 Chronomedical inovation based on circadian biology
2023 - 2026 Creation of multi-scale 4D biology
2022 - 2025 視床下部Prdm13シグナル系による健康寿命調節機構の解明
2021 - 2025 アルツハイマー病保護因子APOE2多型の作用機序の解明と治療薬開発への応用
2020 - 2022 Molecular basis that positively protects hypothalamic function during the aging process

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Papers (16)：

Shogo Tsuji, Cynthia S Brace, Ruiqing Yao, Yoshitaka Tanie, Hirobumi Tada, Nicholas Rensing, Seiya Mizuno, Julio Almunia, Yingyi Kong, Kazuhiro Nakamura, et al. Sleep-wake patterns are altered with age, Prdm13 signaling in the DMH, and diet restriction in mice. Life science alliance. 2023. 6. 6
Tomoya Mizumoto, Tatsuya Yoshizawa, Yoshifumi Sato, Takaaki Ito, Tomonori Tsuyama, Akiko Satoh, Satoshi Araki, Kenichi Tsujita, Masaru Tamura, Yuichi Oike, et al. SIRT7 Deficiency Protects against Aging-Associated Glucose Intolerance and Extends Lifespan in Male Mice. Cells. 2022. 11. 22. 3609-3609
Masae Furukawa, Hirobumi Tada, Jingshu Wang, Mitsuyoshi Yamada, Mie Kurosawa, Akiko Satoh, Noboru Ogiso, Yosuke Shikama, Kenji Matsushita. Molar loss induces hypothalamic and hippocampal astrogliosis in aged mice. Scientific reports. 2022. 12. 1. 6409-6409
Bo Zhang, Dongjun Guo, Lirong Han, Nicholas Rensing, Akiko Satoh, Michael Wong. Hypothalamic orexin and mechanistic target of rapamycin activation mediate sleep dysfunction in a mouse model of tuberous sclerosis complex. Neurobiology of disease. 2020. 134. 104615-104615
Mitsukuni Yoshida, Akiko Satoh, Jonathan B Lin, Kathryn F Mills, Yo Sasaki, Nicholas Rensing, Michael Wong, Rajendra S Apte, Shin-Ichiro Imai. Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice. Cell metabolism. 2019. 30. 2. 329-342

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MISC (4)：

脳による老化制御とエピジェネティクス. Geriatric Medicine. 2023. 61. 29-33
今井眞一郎, 佐藤亜希子. 特集抗老化医療の未来をさぐる : 哺乳類における老化・寿命制御の理解とその社会実装序文. Geriatric Medicine. 2023. 61. 5-7
佐藤亜希子. 脳老化と神経変性疾患における細胞老化. 実験医学. 2022. 40. 401-406
佐藤亜希子. 睡眠と脳内の寿命制御因子. 医学のあゆみ. 2021. 279. 356-359

Books (1)：

Lectures and oral presentations (7)：

視床下部Prdm13系の老化に伴う睡眠変化における役割
(第22回日本再生医療学会総会シンポジウム 2023)
睡眠調節を介した視床下部による老化寿命制御機構
(第100回日本生理学会学術総会大会シンポジウム 2023)
高脂肪食下における背内側部特異的Prdm13欠損が代謝能にもたらす機能変化について
(第100回日本生理学会学術総会大会 2023)
The role of hypothalamic neurons in sleep, aging and longevity
(2022)
睡眠調節を介した老化寿命制御機構について
(レドックスR&D戦略委員会第2回企画シンポジウム 2022)

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