Research field (3):
Nanobioscience
, Pathobiochemistry
, Cell biology
Research theme for competitive and other funds (6):
2024 - 2026 クロススケール核膜孔周辺と核膜孔内の分子輸送システムの解明とその破綻
2022 - 2026 Spatiotemporally tracking of nano-biofilaments phase separation inside the nuclear pore
2023 - 2025 Nanostructural dynamics of novel coronavirus proteins for drug discovery
2023 - 2025 核膜孔テリトリーにおけるゲノムモダリティ2.0
2022 - 2024 Cross-scale approach to investigate nuclear pores
2015 - 2017 Identification and functional analysis of nuclear pore complex components that function to transport beta-catenin between cytoplasm and nucleus
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Papers (50):
Xin Zhang, Keesiang Lim, Yujia Qiu, Masaharu Hazawa, Richard W. Wong. Strategies for the Viral Exploitation of Nuclear Pore Transport Pathways. Viruses. 2025. 17. 2. 151-151
Dini Kurnia Ikliptikawati, Kei Makiyama, Masaharu Hazawa, Richard W Wong. Unlocking the Gateway: The Spatio-Temporal Dynamics of the p53 Family Driven by the Nuclear Pores and Its Implication for the Therapeutic Approach in Cancer. International journal of molecular sciences. 2024. 25. 13
Elma Sakinatus Sajidah, Keesiang Lim, Masaharu Hazawa, Richard W. Wong. Nanoimaging of SARS-CoV-2 viral invasion toward the nucleus and genome. Cell Reports Physical Science. 2024. 102111-102111
Koki Matsumoto, Dini Kurnia Ikliptikawati, Kei Makiyama, Kako Mochizuki, Maho Tobita, Isao Kobayashi, Dominic Chih-Cheng Voon, Keesiang Lim, Kazuma Ogawa, Ikuo Kashiwakura, et al. Phase-separated super-enhancers confer an innate radioresistance on genomic DNA. Journal of Radiation Research. 2024. 65. 4. 482-490
Keesiang Lim, Masaharu Hazawa, Richard W. Wong. Crafty mimicry grants nuclear pore entry to HIV. Cell Host & Microbe. 2024. 32. 4. 441-442
Masaharu Hazawa, Richard Wong. Structural dynamics and new function of nuclear pore complexes. Journal of Japanese Biochemical Society. 2022. 94. 2. 283-287
近藤寛弥, 三代憲司, 羽澤勝治, 羽澤勝治, 羽澤勝治, 岩嶋友紀, 小林亜紀子, 小川数馬, WONG Richard, WONG Richard, et al. 新規アミノシクロプロペノン化合物はBRD4依存的なNUP210の発現を阻害し,がん細胞の増殖を抑制する. 日本生化学会大会(Web). 2021. 94th
近藤寛弥, 三代憲司, 羽澤勝治, 羽澤勝治, 羽澤勝治, 岩嶋友紀, 小林亜紀子, 小川数馬, RICHARD Wong, RICHARD Wong, et al. 新規アミノシクロプロペノン化合物はBRD4依存的NUP210の発現を阻害し,がん細胞の増殖を抑制する. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
Patents (1):
Sample preparation method for observation of cell organelles by high-speed atomic force microscopy
Lectures and oral presentations (19):
Nanoimaging of SARS-CoV-2 viral invasion toward the nuclear pore territories
(OIST - NanoLSI Joint Symposium "Exploring Uncharted Nanoscale Frontiers in Life Sciences" 2024)
Nuclear pore proteins facilitate p53 transport surveillance in cancer cells
(15th Nucleocytoplasmic Transport meeting, Presqu'Ile de Giens, FRANCE 2024)
Surveillance of p53 Transport by Nuclear Pores in Glioblastoma
(Surveilling Disorder workshop: Cross-Talk Between Protein Quality Control & the Nuclear Pore Complex, in Haarlem, the NETHERLANDS 2024)