KIMURA Toru

Affiliation and department：

Research field (1)： Pharmacology

Research keywords (5)：アミノ酸 , 有機酸 , 多発性嚢胞腎 , cancer , transporter

Research theme for competitive and other funds (14)：

2022 - 2025 アミノ酸輸送体を標的とした新規肝嚢胞治療薬の開発
2020 - 2023 Neuromedin Uのアレルギー性鼻炎の病態への関与と画期的な創薬への解析
2019 - 2022 Therapeutic strategy of ADPKD by anti-amino acid treatment
2016 - 2020 Clarification the regulation of short chain fatty acids transport function in the liver.
2015 - 2018 inhibition of cancer progression by regulation of amino acid transporters

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Papers (48)：

Masaru Takada, Daisuke Fukuhara, Toshihiko Takiura, Yukino Nishibori, Masashi Kotani, Zentaro Kiuchi, Akihiko Kudo, Olga Beltcheva, Noriko Ito-Nitta, Kazuhiro R Nitta, et al. Involvement of GLCCI1 in mouse spermatogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023. 37. 1. e22680
Ichiro Hada, Akira Shimizu, Hiromu Takematsu, Yukino Nishibori, Toru Kimura, Toshiyuki Fukutomi, Akihiko Kudo, Noriko Ito-Nitta, Zentaro Kiuchi, Jaakko Patrakka, et al. A Novel Mouse Model of Idiopathic Nephrotic Syndrome Induced by Immunization with the Podocyte Protein Crb2. Journal of the American Society of Nephrology : JASN. 2022. 33. 11. 2008-2025
Shohei Takahashi, Daisuke Fukuhara, Toru Kimura, Toshiyuki Fukutomi, Eriko Tanaka, Naoaki Mikami, Ichiro Hada, Hiromu Takematsu, Yukino Nishibori, Yoshihiro Akimoto, et al. USP40 deubiquitinates HINT1 and stabilizes p53 in podocyte damage. Biochemical and biophysical research communications. 2022. 614. 198-206
Yorihisa Moro, Yasunao Kogashiwa, Hiroyuki Sakurai, Ryo Takahashi, Toru Kimura, Masataka Hirasaki, Yoshifumi Matsumoto, Masashi Sugasawa, Naoyuki Kohno. In Vitro Study of the Anti-cancer Effect of Alternate-day 5-Fluorouracil in Head and Neck Cancer Cells. Anticancer research. 2019. 39. 11. 6041-6047
Marunaka K, Fujii N, Kimura T, Furuta T, Hasegawa H, Matsunaga T, Endo S, Ikari A. Rescue of tight junctional localization of a claudin-16 mutant D97S by antimalarial medicine primaquine in Madin-Darby canine kidney cells. Scientific reports. 2019. 9. 1. 9647-9647

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MISC (86)：

三上直朗, 川西邦夫, 羽田伊知郎, 田中絵里子, 木村徹, 宮東昭彦, 秋元義弘, 松阪泰二, 長田道夫, 楊國昌. Ubiquitin specific protease-40ノックアウトマウスにおけるポドサイト障害の増悪. 日本小児腎臓病学会雑誌. 2020. 33. 1Suppl. 77-77
木村徹. 生物系薬学コレステロールはトランスポーターを介してmTORC1活性を調節する. ファルマシア. 2017. 53. 12. 1214-1214
中村真希子, Stiburkova Blanka, 木村徹, 櫻井裕之, 市田公美. 尿酸トランスポーターURAT1遺伝子重複変異モデルにおける尿酸輸送活性及びURAT1発現局在の検討. 痛風と核酸代謝. 2015. 39. 1. 33-33
中村真希子, Stiburkova Blanka, 木村徹, 櫻井裕之, 市田公美. 尿酸トランスポーターURAT1遺伝子重複変異モデルにおける尿酸輸送活性及びURAT1発現局在の検討. 日本痛風・核酸代謝学会総会プログラム抄録集. 2015. 48回. 55-55
大槻英男, 木村徹, 山賀貴, 末弘淳一, 櫻井裕之. 前立腺癌アンドロゲン受容体高発現細胞株におけるロイシン輸送トランスポータ. 日本薬理学会関東部会プログラム・要旨集. 2015. 132nd

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Education (3)：

1999 - 2002 Toyama Medical and Pharmaceutical University
1997 - 1999 Toyama Medical and Pharmaceutical University
1993 - 1997 Toyama Medical and Pharmaceutical University

Professional career (1)：

博士(薬学) (富山医科薬科大学)

Work history (4)：

2023/04 - 現在 Josai University Faculty of Pharmaceutical Sciences Department of Pharmaceutical
2014/04 - 現在 Kyorin University Faculty of Medicine
2006/04 - 2014/03 Kyorin University School of Medicin
2002/04 - 2006/03 Yale University School of Medicine Cellular & Molecular Physiology postdoctoral associate

Association Membership(s) (2)：

THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE PHARMACOLOGICAL SOCIETY

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