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J-GLOBAL ID:201801001436329878   Update date: Feb. 21, 2025

Nagata Ryuhei

ナガタ リュウヘイ | Nagata Ryuhei
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Affiliation and department:
Job title: Assistant Professor
Homepage URL  (1): https://scholar.google.co.jp/citations?hl=ja&user=xLaTxv4AAAAJ&view_op=list_works&sortby=pubdate
Research field  (2): Molecular biology ,  Structural biochemistry
Research keywords  (2): 代謝酵素 ,  構造生物学
Research theme for competitive and other funds  (4):
  • 2022 - 2025 Seeking pyrophosphate-dependent protein kinase
  • 2019 - 2022 ポリケタイド合成酵素の基質受け渡し機構の解明を目指した高分解能構造解析
  • 2019 - 2022 医薬資源として有望なヒドロキサム酸を合成する酵素の機構解明と合理的改変法の確立
  • 2016 - 2018 酵素の工業利用のためにATP依存性のリン酸化酵素をピロリン酸依存性に改良する方法
Papers (6):
  • Ryuhei Nagata, Makoto Nishiyama, Tomohisa Kuzuyama. Substrate Recognition Mechanism of a Trichostatin A-Forming Hydroxyamidotransferase. Biochemistry. 2023. 62. 12. 1833-1837
  • Ryuhei Nagata, Hironori Suemune, Masaya Kobayashi, Tetsuro Shinada, Kazuo Shin-ya, Makoto Nishiyama, Tomoya Hino, Yusuke Sato, Tomohisa Kuzuyama, Shingo Nagano. Structural Basis for the Prenylation Reaction of Carbazole-Containing Natural Products Catalyzed by Squalene Synthase-like Enzymes. Angewandte Chemie International Edition. 2022. 61. 20. e202117430
  • Yasunobu Mori, Hiroki Kawamura, Takaaki Sato, Takayuki Fujita, Ryuhei Nagata, Masahiro Fujihashi, Kunio Miki, Haruyuki Atomi. Identification and enzymatic analysis of an archaeal ATP-dependent serine kinase from the hyperthermophilic archaeon Staphylothermus marinus. Journal of Bacteriology. 2021. 203. 16. e00025-21
  • Ryuhei Nagata, Masahiro Fujihashi, Takaaki Sato, Haruyuki Atomi, Kunio Miki. Identification of a pyrophosphate-dependent kinase and its donor selectivity determinants. Nature Communications. 2018. 9. 1765
  • Ryuhei Nagata, Masahiro Fujihashi, Hiroki Kawamura, Takaaki Sato, Takayuki Fujita, Haruyuki Atomi, Kunio Miki. Structural Study on the Reaction Mechanism of a Free Serine Kinase Involved in Cysteine Biosynthesis. ACS Chemical Biology. 2017. 12. 6. 1514-1523
more...
MISC (6):
  • 永田隆平, 葛山智久. スクアレン合成酵素に似た酵素による芳香族化合物のプレニル化反応の仕組み. 化学と生物. 2023. 61. 6. 260-262
  • 永田隆平, 葛山智久. 末端ヒドロキサム酸基を合成する酵素の基質認識機構の解明. Photon Factory Activity Report 2022. 2023
  • 永田隆平, 小林正弥, 西山真, 葛山智久. 【プレスリリース】2つの酵素の特徴をあわせ持つ酵素の反応機構の解明. 2022
  • 永田隆平, 藤橋雅宏. ATPでなくピロリン酸を利用する新規リン酸化酵素の基質認識機構. 化学と生物. 2018. 56. 12. 779-780
  • 永田隆平, 藤橋雅宏, 三木邦夫. 【プレスリリース】お財布にも環境にもやさしい化学反応を発見 -新規リン酸化酵素がATPでなくピロリン酸を利用する仕組み-. 2018
more...
Lectures and oral presentations  (28):
  • The substrate recognition mechanism of an enzyme involved in biosynthesis of the terminal hydroxamic acid group of trichostatin A
    (2024)
  • 末端ヒドロキサム酸基の生合成を担う酵素hydroxyamidotransferase の基質認識機構(口頭)
    (日本結晶学会令和5年度大会 2023)
  • Trichostatin A 生合成におけるヒドロキサム酸基の生合成機構の解明(口頭)
    (天然有機化合物討論会 2022)
  • ヒドロキサム酸基の生合成を担う酵素TsnB9の基質認識機構に関する研究(口頭)
    (日本農芸化学会2022年度大会 2022)
  • 真菌Eupenicillium ludwigii由来PKSチオエステラーゼElbBの基質認識機構に関する構造解析(口頭)
    (日本農芸化学会2022年度大会 2022)
more...
Works (15):
  • 8HAR: SAH-bound C-Methyltransferase Fur6 from Streptomyces sp. KO-3988
    Noguchi, T, Nagata, R, Tomita, T, Kuzuyama, T 2023 -
  • Front Cover Art of Biochemistry | Vol. 62, No. 12
    Ryuhei Nagata 2023 -
  • 7YLZ: Unliganded form of hydroxyamidotransferase TsnB9
    Nagata, R, Nishiyama, M, Kuzuyama, T 2023 -
  • 7VWT: Carbazole Prenyl Transferase CqsB4
    Suemune, H, Nagata, R, Kuzuyama, T, Nagano, S 2022 -
  • 7VWS: Carbazole Prenyl Transferase LvqB4
    Suemune, H, Nagata, R, Kuzuyama, T, Nagano, S 2022 -
more...
Education (3):
  • 2014 - 2018 Kyoto University Graduate School of Science Division of Chemistry
  • 2012 - 2014 Kyoto University Graduate School of Science Division of Chemistry
  • 2008 - 2012 Kyoto University Faculty of Science Faculty of Science
Professional career (1):
  • 博士(理学) (京都大学)
Work history (6):
  • 2024/10 - 現在 Nagoya University Graduate School of Bioagricultural Sciences Department of Applied Biosciences Assistant Professor
  • 2022/04 - 2024/09 The University of Tokyo Department of Biological Sciences, Graduate School of Science Project Research Associate
  • 2019/04 - 2022/03 The University of Tokyo Graduate School of Agricultural and Life Sciences Biotechnology
  • 2020/05 - 2020/09 Ochanomizu University Faculty of Science
  • 2018/04 - 2019/03 The University of Tokyo Biotechnology Research Center
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Committee career (1):
  • 2023/04 - 2025/03 PF News 編集委員会 外部編集委員
Awards (1):
  • 2015/09 - 日本生物高分子学会 優秀発表賞
Association Membership(s) (5):
Informatics In Biology, Medicine and Pharmacology ,  JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY ,  日本蛋白質科学会 ,  THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN ,  日本生化学会
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