Tanegashima Kosuke

Research field (1)： Molecular biology

Research keywords (4)： tumor immunity , DNA sensing , CXCL14 , CpG DNA

Research theme for competitive and other funds (7)：

2021 - 2024 自然免疫活性化核酸受容体による腫瘍免疫誘導メカニズム
2018 - 2021 Mecanisms of cooperation between CXCL14 and DNA for activation of innate immune responces and tumor immunity
2013 - 2016 Regulation of macrophage in adipose tissue by CXCL14 and its receptor.
2011 - 2013 新奇ストレス環境における摂食抑制とケモカインシグナル
2010 - 2012 Regulation of morphogenetic movements by a guanine nucleotide-exchange factor involved in Wnt-PCP pathway

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Papers (38)：

Rin Miyajima, Kosuke Tanegashima, Naoto Naruse, Masaya Denda, Takahiko Hara, Akira Otaka. Identification of Low-Density Lipoprotein Receptor-Related Protein 1 as a CXCL14 Receptor Using Chemically Synthesized Tetrafunctional Probes. ACS Chemical Biology. 2024
Kazuya Miyashita, Takuya Yagi, Noritaka Kagaya, Azusa Takechi, Chihiro Nakata, Risa Kanda, Hideko Nuriya, Kosuke Tanegashima, Shota Hoyano, Fumiya Seki, et al. Identification of compounds that preferentially suppress the growth of T-cell acute lymphoblastic leukemia-derived cells. Cancer Science. 2023. 114. 10. 4032-4040
Kojiro Tsujihana, Kosuke Tanegashima, Yasuko Santo, Hiroyuki Yamada, Sota Akazawa, Ryuta Nakao, Keiko Tominaga, Risa Saito, Yasumasa Nishito, Ryu-Ichiro Hata, et al. Circadian protection against bacterial skin infection by epidermal CXCL14-mediated innate immunity. Proceedings of the National Academy of Sciences. 2022. 119. 25
Rina Iwase, Naoto Naruse, Miho Nakagawa, Risa Saito, Akira Shigenaga, Akira Otaka, Takahiko Hara, Kosuke Tanegashima. Identification of Functional Domains of CXCL14 Involved in High-Affinity Binding and Intracellular Transport of CpG DNA. The Journal of Immunology. 2021. 207. 2. 459-469
Yokote N, Suzuki-Kosaka MY, Michiue T, Hara T, Tanegashima K. Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis. Int. J. Dev. Biol. 2019. 63. 1-2. 29-35

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MISC (21)：

小松谷啓介, 酒井祥太, 菊池紀仁, 小倉潔, 川島育夫, 平林哲也, 深澤征義, 花田賢太郎, 長田直樹, 種子島幸祐, et al. SARS-CoV-2の脂質ラフトを介した細胞侵入機構の解明. 脂質生化学研究. 2023. 65. 226-228
種子島幸祐, 岩瀬璃奈, 岩瀬璃奈, 中川美帆, 中川美帆, 斎藤理佐, 斎藤理佐, 成瀬公人, 重永章, 大高章, et al. CXCケモカインのCpG ODN細胞内送達活性の分子メカニズム. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
福山美智子, 福山美智子, 井口智弘, 小松谷啓介, 川島育夫, 下仲基之, 種子島幸祐, 原孝彦, 山本正雅, 笠原浩二. ケモカインSDF-1αによるJurkat T細胞移動の脂質ラフトを介するシグナル伝達. 日本生化学会大会(Web). 2019. 92nd
種子島幸祐, 三井貴洋, 三井貴洋, 岩瀬璃奈, 岩瀬璃奈, 成瀬公人, 重永章, 大高章, 原孝彦, 原孝彦, et al. CpG DNAとCXCL14による自然免疫系の協調的な調節メカニズム. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
中川美帆, 中川美帆, 種子島幸祐, 三井貴洋, 三井貴洋, 成瀬公人, 重永章, 大高章, 佐久間啓, 原孝彦, et al. ケモカインCXCL14の脳内ミクログリアに対する働き. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd

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Patents (2)：

Education (2)：

1998 - 2003 The University of Tokyo Graduate School of Arts and Sciences
1994 - 1998 Tokyo Institute of Technology School of Bioscience and Biotechnology

Professional career (1)：

Work history (4)：

Awards (1)：

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