Research theme for competitive and other funds (12):
2023 - 2026 Development of therapeutic strategies to overcome fibrotic barriers to nanomedicine in pancreatic cancer via targeting of extracellular matrix signaling
2024 - 2025 KRAS/MAPKシグナル遮断への膵がんの獲得耐性のSRC family kinase標的化による克服
2022 - 2024 膵がんにおける線維化の治療的制御に基づくナノ薬剤送達戦略の開発
2020 - 2023 The use of 3D cell culture to study the mechanisms underlying aberrant ECM remodeling in pancreatic cancer stroma
2019 - 2020 Modeling and analysis of the pancreatic tumor microenvironment using 3D cell culture techniques
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Papers (24):
Hiroyoshi Y. Tanaka, Takuya Nakazawa, Takuya Miyazaki, Horacio Cabral, Atsushi Masamune, Mitsunobu R. Kano. Targeting ROCK2 improves macromolecular permeability in a 3D fibrotic pancreatic cancer microenvironment model. Journal of Controlled Release. 2024. 369. 283-295