Rchr
J-GLOBAL ID：201801002377417217   Update date: Feb. 01, 2024

Takushi Namba

ナンバ タクシ | Takushi Namba
Affiliation and department：
Kochi University

About Kochi University


Job title： Associate professor
Research field  (2)： Cell biology ,  Pharmaceuticals - health and biochemistry
Research keywords  (4)： ミトコンドリア ,  小胞体 ,  ストレス応答 ,  細胞生物学
Research theme for competitive and other funds  (21)：
  • 2021 - 2023 皮膚線維芽細胞における老化とオルガネラコミュニケーションの破綻
  • 2019 - 2022 Mitochondrial function regulated by the endoplasmic reticulum membrane protein BAP31 is associated with neurological disorders.
  • 2020 - 2022 生活ストレスが小胞体-ミトコンドリア接触領域における情報交換機構の破綻と細胞老化を引き起こすメカニズムの解析
  • 2020 - 2022 ミトコンドリア機能を維持した脂肪細胞の分化誘導を促進する新規化合物の機能解析と肥満予防効果の探索
  • 2020 - 2021 細胞の新たな老化機構である小胞体-ミトコンドリア情報機構の破綻が老化様細胞を誘導するメカニズムの解析
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Papers (42)：
  • Kayo Machihara, Shoma Oki, Yuka Maejima, Sou Kageyama, Ayumu Onda, Yurino Koseki, Yasuyuki Imai, Takushi Namba. Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts. ISCIENCE. 2023. 26. 7
  • Kayo Machihara, Sou Kageyama, Shoma Oki, Hiroki Makino, Masamichi Sasaki, Hiroyasu Iwahashi, Takushi Namba. Lotus germ extract rejuvenates aging fibroblasts via restoration of disrupted proteostasis by the induction of autophagy. Aging. 2022. 14. 19. 7662-7691
  • Takuya Yoshioka, Yasuhiro Igarashi, Takushi Namba, Shohei Ueda, Ivy Grace Umadhay Pait, Takuya Nihira, Shigeru Kitani. Lavencidin, a polyene macrolide antibiotic from Streptomyces lavendulae FRI-5. The Journal of antibiotics. 2021. 74. 5. 359-362
  • Kayo Machihara, Takushi Namba. Kuanoniamine C stimulates bortezomib-induced cell death via suppression of glucose-regulated protein 78 in osteosarcoma. Biochemical and biophysical research communications. 2020. 527. 1. 289-296
  • Kayo Machihara, Takushi Namba. BAP31 Inhibits Cell Adaptation to ER Stress Conditions, Negatively Regulating Autophagy Induction by Interaction with STX17. Cells. 2019. 8. 11
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MISC (10)：
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Lectures and oral presentations  (12)：
  • Rejuvenating effect of lotus germ extract on senescent fibroblast via DAPK1-Beclin-1 pathway induced autophagy
    (The 6th International Cell Senescence Association (ICSA) Conference 2021)
  • Bap31 Regulates Mitochondrial Function In ER-Mitochondria Contact Site.
    (ASCB/EMBO 2019 meeting. 2019)
  • 小胞体-ミトコンドリアタンパク質複合体によるミトコンドリアの恒常性維持機構の解明
    (第13回小胞体ストレス研究会 2018)
  • 小胞体膜タンパク質B-cell receptor-associated protein 31はautophagyとapoptosisの誘導を制御する
    (2017年度生命科学系学会合同年次大会 2017)
  • The suppression of endoplasmic reticulum function is a new anti-cancer target
    (The 11th International Kuroshio Science Symposium 2017)
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Education (3)：
  • 2007 - 2010 Kumamoto University Graduate School of Pharmaceutical Sciences
  • 2005 - 2007 Kumamoto University Graduate School of Pharmaceutical Sciences
  • - 2005 Okayama University Faculty of Pharmaceutical Sciences
Awards (4)：
  • 2017/03 - 高知大学 若手研究奨励賞
  • 2014/11 - 臨床ストレス応答学会 若手奨励賞受賞
  • 2013/04 - The AACR Annual Meeting AACR-Bristol-Myers Squibb Oncology Scholar-in-Training Award
  • 2010/10 - The 15th Congress of the Asian Pacific Society of Respiratory Travel Grant Award
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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