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J-GLOBAL ID：201801003481922280 Update date: Mar. 05, 2025

Tsutiya Atsuhiro

ツチヤアツヒロ | Tsutiya Atsuhiro

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Affiliation and department：

Research field (3)： Molecular biology , Animals: biochemistry, physiology, behavioral science , Neuroscience - general

Research keywords (8)： Mass spectrometry , Synapse , Protein-protein interaction , BioID , Biochemistory , Immunostaining , Cell culture , Neuroscience

Research theme for competitive and other funds (8)：

2023 - 2025 ライリンによるLDL受容体調節機構の解明-ライリンを標的とした脂質異常症治療薬の開発-
2023 - 2024 layilinを中心としたがん悪性化機構の解明
2022 - 2023 サイクリン依存性キナーゼ1(CDK1)の活性化におけるlayilin(ライリン)の役割の解明
2021 - 2022 ライリンの新規相互作用分子の同定-近位依存性ビオチン標識を用いて-
2019 - 2021 近位依存性ビオチン標識を用いたライリンの新規相互作用分子の同定による機能解明

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Papers (18)：

Masaaki Sato, Kouhei Nagai, Toshiyuki Sato, Ryo Yoshimoto, Yuto Shibano, Minori Shibahara, Haruka Satokawa, Masayuki Anzai, Teisuke Uchida, Atsuhiro Tsutiya, et al. Aberrant oxidative modifications of neutrophil myeloperoxidase in anti-neutrophil cytoplasmic antibodies-associated vasculitis. Journal of Proteomics. 2025. 105412-105412
Mitsumi Arito, Atsuhiro Tsutiya, Masaaki Sato, Kazuki Omoteyama, Toshiyuki Sato, Yusei Motonaga, Naoya Suematsu, Manae S Kurokawa, Tomohiro Kato. Role of layilin in regulating mitochondria-mediated apoptosis: a study on B cell lymphoma (BCL)-2 family proteins. BMC molecular and cell biology. 2024. 25. 1. 24-24
Suzuka Shiono, Atsuhiro Tsutiya, Ritsuko Ohtani-Kaneko. Early Detection of Male-Predominant Phenotypes in the Pattern of Ultrasonic Vocalizations Emitted by Autism Spectrum Disorder Model (Crmp4-Knockout) Mice. Brain Sciences. 2022. 12. 5. 666-666
Atsuhiro Tsutiya, Mitsumi Arito, Takuma Tagashira, Masaaki Sato, Kazuki Omoteyama, Toshiyuki Sato, Naoya Suematsu, Manae S. Kurokawa, Tomohiro Kato. Layilin promotes mitochondrial fission by cyclin-dependent kinase 1 and dynamin-related protein 1 activation in HEK293T cells. Biochemical and Biophysical Research Communications. 2021. 549. 143-149
Kazuki Omoteyama, Toshiyuki Sato, Masaaki Sato, Atsuhiro Tsutiya, Mitsumi Arito, Naoya Suematsu, Manae S. Kurokawa, Tomohiro Kato. Identification of novel substrates of a disintegrin and metalloprotease 17 by specific labeling of surface proteins. Heliyon. 2020. 6. 12. e05804-e05804

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MISC (13)：

川口拓哉, 有戸光美, 土屋貴大, 加藤智啓, 北川博昭. ライリンの神経芽腫におけるMYCN遺伝子増幅に対する影響. 日本小児外科学会雑誌. 2021. 57. 2. 392-392
黒川真奈絵, 佐藤利行, 佐藤政秋, 土屋貴大, 表山和樹, 有戸光美, 末松直也, 加藤智啓. 再発性多発軟骨炎のバイオマーカー候補となる血清ペプチドの検出. 電気泳動. 2020. 64. Suppl. s43-s43
川口拓哉, 有戸光美, 土屋貴大, 加藤智啓, 北川博昭. 神経芽腫及び神経膠腫細胞におけるがん幹細胞性へのライリンの影響. 日本小児外科学会雑誌. 2020. 56. 5. 629-629
佐藤利行, 佐藤政秋, 表山和樹, 土屋貴大, 有戸光美, 末松直也, 加藤智啓, 黒川真奈絵. 再発性多発軟骨炎における血清ペプチドプロファイルの解析. 日本生化学会大会プログラム・講演要旨集. 2020. 93回. [P-610]
佐藤政秋, 佐藤利行, 表山和樹, 土屋貴大, 有戸光美, 末松直也, 加藤智啓, 黒川真奈絵. 顕微鏡的多発血管炎の新規血清ペプチドバイオマーカー候補AC13のMALDI-TOF/MSによる定量. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [3P-305]

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Lectures and oral presentations (20)：

Substrate-specific neurite growth controlled by Ndr2 kinase through α1 integrin expression
(11th FENS Forum of Neuroscience, Berlin 2018 2018)
The functional alternations caused by Crmp4 mutation and their similarities to ASD characteristics and sexual dimorphism
(Collaboration Seminar on Development, Physiology & Ecology At Hakusan Campus, Toyo University 2018)
The function of CRMP4 in the brain development -Mainly focused on the olfactory bulb-
(IUPUI International Scientific Exchange Symposium 2015)
Collapsin response mediator protein 4 (CRMP4) knockout mice showed physiological alterations related to olfactory function
(Society for Neuroscience 2015 2015)
Deletion of Crmp4 results in altered morphology and physiology in the olfactory bulb.
(2015)

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Education (3)：

2013 - 2016 Toyo University Graduate School of Life Sciences PhD course
2011 - 2013 Toyo University Graduate School of Life Sciences Master course
2007 - 2011 Toyo University Department of Life Sciences

Professional career (1)：

博士(生命科学)

Work history (5)：

2017/06 - 現在 St. Marianna University School of Medicine Assistant Professor
2017/01 - 2017/05 Otto-von-Guericke University Department of Genetics & Molecular Neurobiology Scientific Assistant
2016/06 - 2016/12 Otto-von-Guericke University Department of Genetics & Molecular Neurobiology Postdoctoral Guest researcher
2016/04 - 2016/05 Toyo University Institute of Life Innovation Studies Researcher
2013/04 - 2016/03 Japan Society for the Promotion of Science Research Fellowship for Young Scientists

Awards (6)：

2021 - 聖マリアンナ医科大学前田賞
2015 - 東洋大学発表優秀賞平成26年度国際シンポジウム
2015 - Joint meeting of the 120th Annual Meeting of The Japanese Association of Anatomists and the 92nd Annual Meeting of The Physiological Society of Japan Best Poster Award
2013 - 日本学生支援機構日本学生支援機構大学院第一種奨学金業績優秀者返還免除
2013 - 東洋大学校友会学生研究奨励賞

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Association Membership(s) (6)：

THE ZOOLOGICAL SOCIETY OF JAPAN , THE JAPANESE ASSOCIATION OF ANATOMISTS , THE JAPANESE ASSOCIATION FOR THE STUDY OF TASTE AND SMELL , Society for neuroscience , THE JAPAN NEUROSCIENCE SOCIETY , 日本生化学会

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