Research field (3)：
Tumor biology
, Biomedical engineering
, Orthopedics
Research keywords (3)：
extracellular matrix
, osteosarcoma
, metastasis
Research theme for competitive and other funds (2)：
2021 - 2024 骨肉腫の足場依存的な肺内増殖メカニズムの解明と肺転移抑制療法への応用
2018 - 2021 Lung fibrosis is a novel therapeutic target to suppress lung metastasis of osteosarcoma
Papers (25)：
Jason J. Northey, Mary-Kate Hayward, Yoshihiro Yui, Connor Stashko, FuiBoon Kai, Janna K. Mouw, Dhruv Thakar, Jonathon N. Lakins, Alastair J. Ironside, Susan Samson, et al. Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk. Cell Stem Cell. 2024. 31. 1. 106-126.e13
Rie Suzuki, Toru Wakamatsu, Keiichi Yoshida, Yukiko Matsuoka, Haruna Takami, Sho Nakai, Hironari Tamiya, Shigeki Kakunaga, Toshinari Yagi, Ken-ichi Yoshida, et al. Genetic characterization of a novel organoid from human malignant giant-cell tumor. Journal of Bone Oncology. 2023. 41. 100486-100486
Yoshihiro Yui, Jun Kumai, Kenta Watanabe, Toru Wakamatsu, Satoru Sasagawa. Lung fibrosis is a novel therapeutic target to suppress lung metastasis of osteosarcoma. International Journal of Cancer. 2022
Toru Wakamatsu, Hisataka Ogawa, Keiichi Yoshida, Yukiko Matsuoka, Kazuko Shizuma, Yoshinori Imura, Hironari Tamiya, Sho Nakai, Toshinari Yagi, Shigenori Nagata, et al. Establishment of Organoids From Human Epithelioid Sarcoma With the Air-Liquid Interface Organoid Cultures. Frontiers in oncology. 2022. 12. 893592-893592
Sonya Liu, Russell Bainer, Yoshihiro Yui, Colin Flinders, Parag Mallick, Valerie Weaver, Shannon Mumenthaler. Characterization of diverging molecular and phenotypic responses under changing extracellular matrix stiffness in MCF10A cells. CANCER RESEARCH. 2016. 76
Russell Bainer, Yoshihiro Yui, Shannon Mumenthaler, Parag Mallick, Ondrej Podlaha, Franziska Michor, Jan Liphardt, Jonathan Licht, Valerie Weaver. 3D extracellular stiffness cues drive localized changes in gene expression. CANCER RESEARCH. 2014. 74. 19
Hongmei Yu, Yoshihiro Yui, Valerie Weaver. Tumor metastasis is modulated by tissue stiffness in MMTV-PyMT breast cancer model. CANCER RESEARCH. 2012. 72
